scholarly journals Overfeeding‐induced weight gain elicits decreases in sex hormone‐binding globulin in healthy males—Implications for body fat distribution

2021 ◽  
Vol 9 (23) ◽  
Author(s):  
Prachi Singh ◽  
Naima Covassin ◽  
Fatima H. Sert‐Kuniyoshi ◽  
Kara L. Marlatt ◽  
Abel Romero‐Corral ◽  
...  

1997 ◽  
Vol 21 (1) ◽  
pp. 33-36 ◽  
Author(s):  
M Zamboni ◽  
F Armellini ◽  
E Turcato ◽  
P Todisco ◽  
D Gallagher ◽  
...  




1984 ◽  
Vol 107 (3) ◽  
pp. 413-419 ◽  
Author(s):  
D. Apter ◽  
N.J. Bolton ◽  
G. L. Hammond ◽  
R. Vihko

Abstract. Serum sex hormone binding globulin (SHBG) concentrations were measured by an immunoradiometric assay, as part of a longitudinal study of puberty in girls, and were related to age. pubertal stage, age at menarche, weight, nature of the menstrual cycle and serum concentrations of sex steroids. A slow but very significant decrease was seen in SHBG from 77 nmol/l at 8–10 years of age to about 50 nmol/l after 15 years of age. Serum SHBG concentrations showed weak negative correlations with those of androstenedione and testosterone during puberty. The closest associations found between SHBG and the parameters measured were negative correlations with weight and body fat percentage in both pre-menarcheal and post-menarcheal girls, even after the effect of age was accounted for by calculating partial correlation coefficients. Girls who experienced early menarche (before 13.0 years) had lower SHBG but higher oestradiol serum concentrations at 10.0–15.9 years of age compared to girls with later menarche. In ovulatory menstrual cycles, a significant increase in SHBG was found from the early to the late part of the cycle, whereas no changes took place in anovulatory cycles. Serum concentrations of SHBG showed positive correlations with those of oestradiol and progesterone in specimens taken in the late part of the cycle. In view of the weak relationships between serum SHBG and sex steroid concentrations, and the strong relationships between SHBG, weight and body fat percentage, factors other than steroids have to be considered in the regulation of SHBG levels during puberty.



1991 ◽  
Vol 69 (14) ◽  
pp. 664-668 ◽  
Author(s):  
H. Hauner ◽  
K. Stangl ◽  
K. Burger ◽  
U. Busch ◽  
H. Blömer ◽  
...  


Author(s):  
Maartje Klaver ◽  
Marieke Dekker ◽  
Thomas Schreiner ◽  
Alessandra Fisher ◽  
Guy T'sjoen ◽  
...  


2002 ◽  
Vol 283 (2) ◽  
pp. E284-E294 ◽  
Author(s):  
Tracey Ann Roy ◽  
Marc R. Blackman ◽  
S. Mitchell Harman ◽  
Jordan D. Tobin ◽  
Matthew Schrager ◽  
...  

Muscle mass and strength losses during aging may be associated with declining levels of serum testosterone (T) in men. Few studies have shown a direct relationship between T and muscle mass and strength. Subjects were 262 men, aged 24–90 yr, from the Baltimore Longitudinal Study of Aging, who had T and sex hormone-binding globulin sex hormone-binding globulin (SHBG) measurements, from which the free T index (FTI) was calculated (T/SHBG) from serum samples collected longitudinally since 1963, total body fat mass and arm and leg fat-free mass (FFM) by dual-energy X-ray absorptiometry and arm and leg strength by dynanomometry. Mixed-effects models estimated T and FTI at the time of mass and strength measurements. Age, total body fat, arm and leg FFM, T, and FTI were significantly associated with concentric and eccentric strength. FTI, not T, was modestly, but directly, related to arm and leg strength after fat, arm and leg FFM, height, and age were accounted for and indirectly through body mass. FTI is a better predictor of arm and leg strength than T in aging men.



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