Preparation and characterisation of poly vinyl alcohol/hydroxyapatite nanocomposite via in situ synthesis: a potential material as bone tissue engineering scaffolds

2010 ◽  
Vol 5 (3/4) ◽  
pp. 330 ◽  
Author(s):  
S.A. Poursamar ◽  
F. Orang ◽  
S. Bonakdar ◽  
M. Khorshid Savar
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Vinyl Alcohol ◽  
In Situ Synthesis ◽  
Poly Vinyl Alcohol ◽  
Tissue Engineering Scaffolds

scholarly journals Dual Network Composites of Poly(vinyl alcohol)-Calcium Metaphosphate/Alginate with Osteogenic Ions for Bone Tissue Engineering in Oral and Maxillofacial Surgery

2021 ◽  
Vol 8 (8) ◽  
pp. 107
Author(s):  
Lilis Iskandar ◽  
Lucy DiSilvio ◽  
Jonathan Acheson ◽  
Sanjukta Deb
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Vinyl Alcohol ◽  
Maxillofacial Surgery ◽  
Bone Defects ◽  
Bone Tissue Regeneration ◽  
Poly Vinyl Alcohol ◽  
Oral And Maxillofacial Surgery

Despite considerable advances in biomaterials-based bone tissue engineering technologies, autografts remain the gold standard for rehabilitating critical-sized bone defects in the oral and maxillofacial (OMF) region. A majority of advanced synthetic bone substitutes (SBS’s) have not transcended the pre-clinical stage due to inferior clinical performance and translational barriers, which include low scalability, high cost, regulatory restrictions, limited advanced facilities and human resources. The aim of this study is to develop clinically viable alternatives to address the challenges of bone tissue regeneration in the OMF region by developing ‘dual network composites’ (DNC’s) of calcium metaphosphate (CMP)—poly(vinyl alcohol) (PVA)/alginate with osteogenic ions: calcium, zinc and strontium. To fabricate DNC’s, single network composites of PVA/CMP with 10% (w/v) gelatine particles as porogen were developed using two freeze–thawing cycles and subsequently interpenetrated by guluronate-dominant sodium alginate and chelated with calcium, zinc or strontium ions. Physicochemical, compressive, water uptake, thermal, morphological and in vitro biological properties of DNC’s were characterised. The results demonstrated elastic 3D porous scaffolds resembling a ‘spongy bone’ with fluid absorbing capacity, easily sculptable to fit anatomically complex bone defects, biocompatible and osteoconductive in vitro, thus yielding potentially clinically viable for SBS alternatives in OMF surgery.

scholarly journals Highly porous PHB-based bioactive scaffolds for bone tissue engineering by in situ synthesis of hydroxyapatite

2019 ◽  
Vol 100 ◽  
pp. 286-296 ◽  
Author(s):  
Micaela Degli Esposti ◽  
Federica Chiellini ◽  
Federica Bondioli ◽  
Davide Morselli ◽  
Paola Fabbri
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
In Situ Synthesis ◽  
Bioactive Scaffolds ◽  
Highly Porous

Novel biopolimeric system for bone tissue engineering: crosslinked and plasticized chitosan/poly vinyl alcohol/hydroxiapatite scaffolds

2018 ◽  
Author(s):  
Sergio Andres Pineda Castillo ◽  
Cristian Camilo Bernal Lopez ◽  
Favio Andres Tovar Araujo ◽  
Andres Bernal-Ballen ◽  
Hugo Ramiro Segura-Puello ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol

Novel scaffolds based on hydroxyapatite/poly(vinyl alcohol) nanocomposite coated porous TiO 2 ceramics for bone tissue engineering

2016 ◽  
Vol 42 (1) ◽  
pp. 1530-1537 ◽  
Author(s):  
Liga Stipniece ◽  
Inga Narkevica ◽  
Marina Sokolova ◽  
Janis Locs ◽  
Jurijs Ozolins
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol

Development of electrospun poly (vinyl alcohol)-based bionanocomposite scaffolds for bone tissue engineering

2018 ◽  
Vol 106 (4) ◽  
pp. 1111-1120 ◽  
Author(s):  
Mohammad Saied Enayati ◽  
Tayebeh Behzad ◽  
Pawel Sajkiewicz ◽  
Mohammad Rafienia ◽  
Rouhollah Bagheri ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol
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