scholarly journals Standardized Solanum melongena Extract Presents Protective Effects against Chromosomal Aberrations Induced by Doxorubicin in Wistar Rat Bone Marrow Cells

CYTOLOGIA ◽  
2003 ◽  
Vol 68 (2) ◽  
pp. 177-181 ◽  
Author(s):  
Luciano Ferreira ◽  
José Carlos Tavares Carvalho ◽  
Edson Luis Maistro
1999 ◽  
Vol 22 (2) ◽  
pp. 223-227 ◽  
Author(s):  
Lusânia Maria Greggi Antunes ◽  
Catarina Satie Takahashi

There is considerable interest in identifying dietary compounds which have the capacity to protect against chromosomal aberrations induced by antitumor agents. Fatty acids and their constituents are able to act as free radical scavengers. Doxorubicin (DXR) is an important chemotherapeutic agent, that also induces chromosome aberrations. Rat bone marrow cells treated simultaneously with olive oil (10 ml/kg body weight) and DXR (90 mg/kg body weight) developed significantly fewer chromosomal aberrations and abnormal metaphases than those treated with DXR alone.


Author(s):  
Lusânia M.Greggi Antunes ◽  
Maria Cristina P Araújo ◽  
Joana D'Arc C Darin ◽  
Maria de Lourdes P Bianchi

2008 ◽  
Vol 82 (11) ◽  
pp. 869-873 ◽  
Author(s):  
Paula Lumy Takeuchi ◽  
Lusânia Maria Greggi Antunes ◽  
Catarina Satie Takahashi

2011 ◽  
Vol 28 (9) ◽  
pp. 524-531 ◽  
Author(s):  
Vedat Şekeroğlu ◽  
Zülal Atlı Şekeroğlu ◽  
Haluk Kefelioğlu

Toxicology ◽  
2006 ◽  
Vol 222 (3) ◽  
pp. 225-232 ◽  
Author(s):  
C. Prahalathan ◽  
E. Selvakumar ◽  
P. Varalakshmi ◽  
P. Kumarasamy ◽  
R. Saravanan

CYTOLOGIA ◽  
2005 ◽  
Vol 70 (3) ◽  
pp. 303-308 ◽  
Author(s):  
Fernando Doro Zanoni ◽  
Sérgio Faloni de Andrade ◽  
Jairo Kenupp Bastos ◽  
Edson Luis Maistro

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