5. The skeletal muscle stem cells: biology and use in regenerative medicine

Author(s):  
Mansour Saleh Alsharidah ◽  
Khawaja Husnain Haider ◽  
Elmuataz Elmansi Abdalla ◽  
Salman Afroze Azmi Mohammed
2021 ◽  
Vol 12 (1) ◽  
Author(s):  
F. Relaix ◽  
M. Bencze ◽  
M. J. Borok ◽  
A. Der Vartanian ◽  
F. Gattazzo ◽  
...  

AbstractSkeletal muscle has remarkable regeneration capabilities, mainly due to its resident muscle stem cells (MuSCs). In this review, we introduce recently developed technologies and the mechanistic insights they provide to the understanding of MuSC biology, including the re-definition of quiescence and Galert states. Additionally, we present recent studies that link MuSC function with cellular heterogeneity, highlighting the complex regulation of self-renewal in regeneration, muscle disorders and aging. Finally, we discuss MuSC metabolism and its role, as well as the multifaceted regulation of MuSCs by their niche. The presented conceptual advances in the MuSC field impact on our general understanding of stem cells and their therapeutic use in regenerative medicine.


2012 ◽  
Vol 2 (1) ◽  
pp. 11-21
Author(s):  
Silvia Cristini ◽  
Giulio Alessandri ◽  
Francesco Acerbi ◽  
Daniela Tavian ◽  
Eugenio A. Parati ◽  
...  

2012 ◽  
Vol 2 (1) ◽  
pp. 11-21
Author(s):  
Silvia Cristini ◽  
Giulio Alessandri ◽  
Francesco Acerbi ◽  
Daniela Tavian ◽  
Eugenio A. Parati ◽  
...  

2021 ◽  
pp. 112933
Author(s):  
Ines Lahmann ◽  
Yao Zhang ◽  
Katharina Baum ◽  
Jana Wolf ◽  
Carmen Birchmeier

Sign in / Sign up

Export Citation Format

Share Document