Effect of high levels of human chorionic gonadotropin and estradiol on the severity of hyperemesis gravidarum

Author(s):  
Peng Chiong Tan ◽  
Nugroho C. Tan ◽  
Siti Z. Omar

Abstract: Serum human chorionic gonadotropin (hCG) and estradiol levels are higher in women with hyperemesis gravidarum (HG) than in unaffected pregnant controls. We postulated that higher levels of these hormones may be associated with clinically more severe HG. The aim of this study was to evaluate the effect of maternal hCG and estradiol levels on the severity of HG.: A prospective study was performed on 167 first trimester women hospitalized for HG. Venous blood was taken for hCG and estradiol levels. Scattergrams were plotted for hCG or estradiol levels vs. gestational age. A curve of best fit was drawn. Women were categorized into two groups according to their position above or below the curve. Prolonged hospital stay (≥4 days) was used as a marker for HG severity. Multivariable logistic regression analysis was used to control for differences in characteristics, laboratory results on admission, and treatment received.: After adjustment, high hCG level adjusted odds ratio (AOR) (2.2, 95% CI 1.0–4.9, p=0.04) and hyponatremia AOR (2.8, 95% CI 1.2–6.6, p=0.02) were independently associated with prolonged hospital stay. With bivariate analysis, high estradiol level was not associated with prolonged stay.: High hCG but not estradiol is associated with more severe HG.Clin Chem Lab Med 2009;47:165–71.

2011 ◽  
Vol 19 (3) ◽  
pp. 284-287 ◽  
Author(s):  
Kashif Abbas ◽  
Masood Umer ◽  
Irfan Qadir ◽  
Jaweria Zaheer ◽  
Haroon ur Rashid

Purpose. To identify variables affecting length of hospital stay after total hip replacement (THR) while controlling for potential confounders. Methods. Records of 199 consecutive elective unilateral THRs were reviewed. Clinical and demographic data including age, gender, body mass index, comorbidities, surgical factors (surgical approach, type of prosthesis, use of cement, operating time), anaesthetic factors (type of anaesthesia, ASA physical status), and length of hospital stay were recorded. Results. 64% of patients left hospital within 12 days, 28% within 3 weeks, and 8% after 3 weeks. The median length of hospital stay was longer in women than men (11.5 vs. 9 days, p=0.009), in patients aged >65 years than those younger (13 vs. 9 days, p<0.0001), and in those with American Society of Anesthesiologists (ASA) grades 3 and 4 than grades 1 or 2 (14 vs. 9 days, p<0.0001). A greater proportion of women than men (45% vs. 27%, p=0.007), patients aged >65 years than those younger (61% vs. 37% or 24%, p<0.0001), and those with ASA grades 3 and 4 than grades 1 and 2 (68% vs. 25%, p<0.0001) stayed 12 days or longer. In the multiple regression analysis, the predictors for prolonged hospital stay (≥12 days) were patient age >65 years (p<0.003), female gender (p<0.05), and ASA grades 3 and 4 (p<0.0001). Of the 72 patients with prolonged stay, 7% had no, 26% had one, 42% had 2, and 25% had all 3 predictors. Conclusion. Prolonged hospital stay after THR is largely predetermined by case mix. Our study helps to identify individuals who need longer rehabilitation and more care.


2018 ◽  
pp. 63-67

Estancia hospitalaria prolongada asociada a mortalidad en Hospital Regional Docente de Trujillo, 2014 Prolonged hospital stay associated with mortality in Regional Teaching Hospital in Trujillo, 2014 Marie Herrera-Viloche, Edward Chávez-Cruzado, Carlos Barba-Chirinos, Germán Fiestas-Pflucker, Miguel Tresierra-Ayala Universidad Privada Antenor Orrego DOI: https://doi.org/10.33017/RevECIPeru2015.0010/  Resumen La estancia hospitalaria prolongada, considerada aquella que supera los 13 días, genera costos adicionales al hospital, deficiente accesibilidad a los servicios de hospitalización para nuevos pacientes y riesgos de adquirir infecciones intrahospitalarias, así como una crisis social y familiar. Este estudio pretende determinar si la estancia hospitalaria prolongada se encuentra asociada a mortalidad en los pacientes atendidos en las diferentes salas de hospitalización del  Hospital Regional Docente de Trujillo en el 2014.  Se registraron 11866 hospitalizaciones, y de estos 1193 tuvieron estancia hospitalaria prolongada, de los cuales el 56.58% fueron de sexo masculino y  43.42% de sexo femenino. Los departamentos de medicina y cirugía con 45.1% y 31.3% y los grupo etarios extremos mayores de 61 y menores de 20 con 29.76% y 27.75% fueron los que presentaron estancia hospitalaria prolongada. La asociación pacientes con estancia hospitalaria prolongada y mortalidad, nos da un Odds Radio de 3.276, con IC de 2.615-4.104, con una p=0.0000. Descriptores: Estancia hospitalaria prolongada, mortalidad Abstract Prolonged hospital stay, considered one that exceeds 13 days, generates additional costs to the hospital, poor access to inpatient services for new patients and risk of acquiring nosocomial infections, as well as social and family crisis. This study aims to determine the specialties and age groups associated with prolonged stay of Regional Hospital of Trujillo in 2014. 11866 hospitalizations were recorded, and of these 1193 had prolonged hospital stay, of which 56.58% were male and 43.42 % female. The departments of medicine and surgery with 45.1% and 31.3% and the extreme age group over 61 and under 20 with 29.76% and 27.75% were those with longer hospital stay. Patients with prolonged hospital stay and mortality, gives an odds ratio of 3.276, with IC 2615-4104, with p = 0.0000. Keywords: prolonged hospital stay


Impact ◽  
2020 ◽  
Vol 2020 (7) ◽  
pp. 45-47
Author(s):  
Naoko Fujii

The majority of human beings will be admitted to hospital at some point over the course of their lives. For the more fortunate among us, these hospital stays will be brief and will barely register as a significant experience. However, for others, being admitted for weeks or months at a time will be necessary in order to combat and recover from whatever it was that made admittance to hospital necessary. While it is easy to think of many reasons why a prolonged hospital stay might be undesirable, one that may escape our attention is the clothes that are worn by patients during their stay. Once a patient has been assigned a bed, they are often given a gown which they put on without thought and then lie down. The gowns that are given to patients are generally designed with healthcare professionals in mind. For example, in Japan pyjamas and yukata (bathrobes) are used as hospital gowns because they have a front opening that is easy to use during treatment and nursing care. In addition, the other gowns can be opened from the ankle to the crotch using the zip. Dr Naoko Fujii has focused her career on designing clothes for hospital patients and believes that there is a way to satisfy the practical needs of a hospital and the care it gives at the same time as satisfying the requirements of patients. She is now focusing her attention on this challenge.


2018 ◽  
Vol Volume 10 ◽  
pp. 1359-1369 ◽  
Author(s):  
Rasmus Rivinius ◽  
Matthias Helmschrott ◽  
Arjang Ruhparwar ◽  
Bastian Schmack ◽  
Fabrice F. Darche ◽  
...  

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