Chronic Renal Failure and Renal Replacement Therapy for Children and Adolescents

1989 ◽  
Vol 4 (1) ◽  
Author(s):  
Alfred Drukker
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Replacement Therapy ◽  
Children And Adolescents ◽  
Replacement Therapy

The immune status of uraemic children/adolescents with chronic renal failure and renal replacement therapy

1989 ◽  
Vol 3 (3) ◽  
pp. 305-308 ◽  
Author(s):  
Raphael Drachman ◽  
Menahem Schlesinger ◽  
Hava Shapira ◽  
Alfred Drukker
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Replacement Therapy ◽  
Replacement Therapy ◽  
Immune Status ◽  
Uraemic Children

scholarly journals Nutrition and Outcome on Renal Replacement Therapy of Patients with Chronic Renal Failure Treated by a Supplemented Very Low Protein Diet

2000 ◽  
Vol 11 (4) ◽  
pp. 708-716 ◽  
Author(s):  
MICHEL APARICIO ◽  
PHILIPPE CHAUVEAU ◽  
VALÉRIE DE PRÉCIGOUT ◽  
JEAN-LOUIS BOUCHET ◽  
CATHERINE LASSEUR ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Replacement Therapy ◽  
Nutritional Status ◽  
Replacement Therapy ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Nutritional Parameters ◽  
Low Protein ◽  
Very Low Protein Diet

Abstract. Protein-restricted diets are prescribed in patients with chronic renal failure (CRF) to alleviate uremic symptoms and to slow the progression of CRF. The potential deleterious effects of protein restriction on nutritional status and clinical outcome of patients with CRF have raised concern. In this study, data were collected from 1985 to 1998 on 239 consecutive patients (age 50.2 ± 15.6 yr) with advanced CRF (GFR 13.1 ± 4.8 ml/min) to whom a supplemented very low protein diet (SVLPD) providing 0.3 g protein, 35 kcal, and 5 to 7 mg of inorganic phosphorus per kg per day was administered for a mean duration of 29.6 ± 25.1 mo. The diet was supplemented with essential amino acids and ketoanalogs, calcium carbonate, iron, and multivitamins. During SVLPD, protein intake decreased from 0.85 ± 0.23 to 0.43 ± 0.11 g/kg per d, and body mass index and serum albumin concentration remained unchanged overall. Fourteen patients died during SVLPD; death was unrelated to nutritional parameters. Hemodialysis was initiated after SVLPD in 165 patients at a mean GFR of 5.8 ± 1.5 ml/min. During an average of 54 mo on hemodialysis, mortality was low (2.4% after 1 yr) and correlated to age only, not to nutritional parameters observed at the end of SVLPD. Similar results were obtained in 66 transplanted patients (12 were not dialyzed before transplantation). SVLPD can be safely used in patients with CRF without adverse effects on the clinical and nutritional status of the patients. Due to the preservation of nutritional status and the correction of uremic symptoms, the initiation of dialysis was deferred in these patients. The outcome of patients on renal replacement therapy is not affected by prior treatment with SVLPD during the predialysis phase of CRF.

scholarly journals Can Renal Replacement Be Deferred by a Supplemented Very Low Protein Diet?

1999 ◽  
Vol 10 (1) ◽  
pp. 110-116
Author(s):  
MACKENZIE WALSER ◽  
SYLVIA HILL
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Replacement Therapy ◽  
Replacement Therapy ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Diabetic Patients ◽  
Renal Survival ◽  
Low Protein ◽  
Very Low Protein Diet

Abstract. Patients with chronic renal failure are commonly started on renal replacement therapy (RRT) as soon as (or, in some centers, before) the usual criteria for severity are met,i.e., GFR <10 ml/min for nondiabetic patients and <15 ml/min for diabetic patients. To determine whether RRT can safely be deferred beyond this point, adults with all types of chronic renal failure who met these criteria on presentation (23 patients) or who reached these levels of severity during treatment (53 patients) were managed conservatively until RRT was judged necessary by their chosen dialysis or transplantation team, without input into this decision from the present authors. Patients were prescribed a very low protein diet (0.3 g/kg) plus supplemental essential amino acids and/or ketoacids and followed closely. The intervals between the time at which GFR became less than 10 ml/min (15 ml/min in diabetic patients) and the date at which renal replacement therapy was started were used as estimates of renal survival on nutritional therapy. Kaplan—Meier analysis showed median renal survival of 353 d. Acidosis and hypercholesterolemia were both predictive of shorter renal survival. Signs of malnutrition did not develop. Final GFR averaged 5.6 ± 1.9 ml/min. Two patients died; thus, annual mortality was only 2.5%. Hospitalizations totaled 19 in 93 patient-years of treatment, or 0.2 per year. Thus, these well motivated patients with GFR <10 ml/min (<15 ml/min in diabetic patients) were safely managed by diet and close follow-up for a median of nearly 1 yr without dialysis. It is concluded that further study of this approach is indicated.

Adiponectin, leptin and thyroid hormones in patients with chronic renal failure and on renal replacement therapy: are they related?

2005 ◽  
Vol 21 (1) ◽  
pp. 145-152 ◽  
Author(s):  
Jolanta Malyszko ◽  
Jacek Malyszko ◽  
Slawomir Wolczynski ◽  
Michal Mysliwiec
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Replacement Therapy ◽  
Thyroid Hormones ◽  
Replacement Therapy

scholarly journals hyperkeratotic uremic stomatitis revealing decompensation of chronic kidney disease

2021 ◽  
Author(s):  
eya moussaoui ◽  
wahbi ben salha ◽  
Baderedine Sriha ◽  
lamia oualha ◽  
nabiha douki
Keyword(s):  
Chronic Kidney Disease ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Replacement Therapy ◽  
Kidney Disease ◽  
Replacement Therapy ◽  
Rare Manifestation

Uremic stomatitis is a rare manifestation associated with longstanding uremia in chronic renal failure patients. Its evolution is favorable with earlier institution of renal replacement therapy. We report a case of hyperkeratotic uremic stomatitis that revealed decompensation of chronic kidney disease.

scholarly journals Limb amputation on renal replacement therapy

2000 ◽  
Vol 24 (1) ◽  
pp. 7-12 ◽  
Author(s):  
L. W. Fleming ◽  
C. P. U. Stewart ◽  
I. S. Henderson ◽  
A. S. Jain
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Replacement Therapy ◽  
Replacement Therapy ◽  
Diabetic Group ◽  
Limb Amputation ◽  
Diabetic Patients ◽  
Course Of Illness ◽  
Survival Patterns

Ten (10) diabetic and 7 nondiabetic patients on renal replacement therapy have undergone limb amputation in the authors’ unit in the 1988 to 1996 period. The article examines the course of illness and survival patterns in this distinct and increasing subset in the amputee population. Rehabilitation and survival were significantly better in the diabetic group and it is recommended that it would be helpful for both prognosis and analysis if the subset of amputees on treatment for chronic renal failure is further divided into diabetic and nondiabetic subsets.

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