scholarly journals Optimal Individualized Treatments in Resource-Limited Settings

2016 ◽  
Vol 12 (1) ◽  
pp. 283-303 ◽  
Author(s):  
Alexander R. Luedtke ◽  
Mark J. van der Laan

Abstract An individualized treatment rule (ITR) is a treatment rule which assigns treatments to individuals based on (a subset of) their measured covariates. An optimal ITR is the ITR which maximizes the population mean outcome. Previous works in this area have assumed that treatment is an unlimited resource so that the entire population can be treated if this strategy maximizes the population mean outcome. We consider optimal ITRs in settings where the treatment resource is limited so that there is a maximum proportion of the population which can be treated. We give a general closed-form expression for an optimal stochastic ITR in this resource-limited setting, and a closed-form expression for the optimal deterministic ITR under an additional assumption. We also present an estimator of the mean outcome under the optimal stochastic ITR in a large semiparametric model that at most places restrictions on the probability of treatment assignment given covariates. We give conditions under which our estimator is efficient among all regular and asymptotically linear estimators. All of our results are supported by simulations.

Geophysics ◽  
1986 ◽  
Vol 51 (11) ◽  
pp. 2160-2161 ◽  
Author(s):  
N. R. Hill ◽  
I. Lerche

We recently investigated the behavior of acoustic wave reflection in a medium with a single rough interface with acoustic speed [Formula: see text] and density[Formula: see text] above (below) the interface (Lerche and Hill, 1985). We used mean‐field techniques (Howe, 1971; Karal and Keller, 1964; Frisch, 1968) to find a closed‐form expression for the mean reflected field, and in particular we examined the case where the roughness is on a much smaller scale than the wavelength of the incident energy. We derived a closed‐form expression which is accurate to second order in roughness height.


IEEE Access ◽  
2021 ◽  
pp. 1-1
Author(s):  
Yassine Zouaoui ◽  
Larbi Talbi ◽  
Khelifa Hettak ◽  
Naresh K. Darimireddy

2021 ◽  
Vol 48 (3) ◽  
pp. 91-96
Author(s):  
Shigeo Shioda

The consensus achieved in the consensus-forming algorithm is not generally a constant but rather a random variable, even if the initial opinions are the same. In the present paper, we investigate the statistical properties of the consensus in a broadcasting-based consensus-forming algorithm. We focus on two extreme cases: consensus forming by two agents and consensus forming by an infinite number of agents. In the two-agent case, we derive several properties of the distribution function of the consensus. In the infinite-numberof- agents case, we show that if the initial opinions follow a stable distribution, then the consensus also follows a stable distribution. In addition, we derive a closed-form expression of the probability density function of the consensus when the initial opinions follow a Gaussian distribution, a Cauchy distribution, or a L´evy distribution.


2021 ◽  
Vol 2021 (6) ◽  
Author(s):  
Vivek Kumar Singh ◽  
Rama Mishra ◽  
P. Ramadevi

Abstract Weaving knots W(p, n) of type (p, n) denote an infinite family of hyperbolic knots which have not been addressed by the knot theorists as yet. Unlike the well known (p, n) torus knots, we do not have a closed-form expression for HOMFLY-PT and the colored HOMFLY-PT for W(p, n). In this paper, we confine to a hybrid generalization of W(3, n) which we denote as $$ {\hat{W}}_3 $$ W ̂ 3 (m, n) and obtain closed form expression for HOMFLY-PT using the Reshitikhin and Turaev method involving $$ \mathrm{\mathcal{R}} $$ ℛ -matrices. Further, we also compute [r]-colored HOMFLY-PT for W(3, n). Surprisingly, we observe that trace of the product of two dimensional $$ \hat{\mathrm{\mathcal{R}}} $$ ℛ ̂ -matrices can be written in terms of infinite family of Laurent polynomials $$ {\mathcal{V}}_{n,t}\left[q\right] $$ V n , t q whose absolute coefficients has interesting relation to the Fibonacci numbers $$ {\mathrm{\mathcal{F}}}_n $$ ℱ n . We also computed reformulated invariants and the BPS integers in the context of topological strings. From our analysis, we propose that certain refined BPS integers for weaving knot W(3, n) can be explicitly derived from the coefficients of Chebyshev polynomials of first kind.


Author(s):  
M.J. Cañavate-Sánchez ◽  
A. Segneri ◽  
S. Godi ◽  
A. Georgiadis ◽  
S. Kosmopoulos ◽  
...  

2004 ◽  
Vol 40 (19) ◽  
pp. 1192 ◽  
Author(s):  
J. Pérez ◽  
J. Ibáñez ◽  
L. Vielva ◽  
I. Santamaría

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