Steroids from the South China Sea Gorgonian Coral Muricella flexuosa

2011 ◽  
Vol 66 (6) ◽  
pp. 635-640
Author(s):  
Ping Wang ◽  
Shu-Hua Qi ◽  
Kai-Sheng Liu ◽  
Li-Si Huang ◽  
Fei He ◽  
...  
Keyword(s):  
South China Sea ◽  
Cell Lines ◽  
Cancer Cell ◽  
South China ◽  
2D Nmr ◽  
The South China Sea ◽  
The South ◽  
Gorgonian Coral ◽  
China Sea ◽  
Spectroscopic Analyses

Four new steroidal glycosides and a new steriod linked with a 4-hydroxyphenylmethylene group, namely muricellasteroids A- E (1 - 5), together with one known steroidal glycoside analog, 22α,2ʹ,3ʹ,4ʹ-O-tetraacetyl-27-O-[β -D-arabino-pyranosyl-oxy]-20β -hydroxy-cholest-4- ene-3-one (6), were isolated from the EtOH/CH2Cl2 extracts of the South China Sea gorgonian coral Muricella flexuosa. The structures of 1 - 5 were established by means of 1D- and 2D-NMR and other spectroscopic analyses. Compounds 1 - 3 and 5 - 6 showed moderate cytotoxicity against A375, K562, and A549 cancer cell lines.

scholarly journals Carbamate derivatives and sesquiterpenoids from the South China Sea gorgonian Melitodes squamata

2012 ◽  
Vol 8 ◽  
pp. 170-176 ◽  
Author(s):  
Li-Si Huang ◽  
Fei He ◽  
Hui Huang ◽  
Xiao-Yong Zhang ◽  
Shu-Hua Qi
Keyword(s):  
Antibacterial Activity ◽  
South China Sea ◽  
South China ◽  
Natural Compounds ◽  
The South China Sea ◽  
The South ◽  
Gorgonian Coral ◽  
China Sea ◽  
Spectroscopic Analyses ◽  
Marine Natural Compounds

Five carbamate derivatives, obtucarbamates C and D (1, 2), dimethyl ((carbonylbis(azanediyl))bis(2-methyl-5,1-phenylene))dicarbamate (3), obtucarbamates A and B (4, 5), and four aromadendrane-type sesquiterpenoids, (+)-4β-N-methenetauryl-10β-methoxy-1β,5α,6β,7β-aromadendrane (6), (−)-4β-N-methenetauryl-10β-methoxy-1β,5β,6α,7α-aromadendrane (7), (−)-4α,10β-aromadendranediol (8), (+)-4β,10β-aromadendranediol (9) were obtained from the South China Sea gorgonian coral Melitodes squamata Nutting. Compounds 1, 2, 6, and 7 were new, and their structures were established by spectroscopic analyses. Compounds 6 and 7 contained a taurine group that was rarely found in marine natural compounds, and 7 showed moderate antibacterial activity. The possible biosynthesis routes of 1–5 were conjectured.

Isolation of a new butenolide from the South China Sea gorgonian coral Subergorgia suberosa

2013 ◽  
Vol 28 (3) ◽  
pp. 150-155 ◽  
Author(s):  
Jun Zhang ◽  
Yan Liang ◽  
Xiao-Jian Liao ◽  
Zhou Deng ◽  
Shi-Hai Xu
Keyword(s):  
South China Sea ◽  
South China ◽  
The South China Sea ◽  
The South ◽  
Gorgonian Coral ◽  
China Sea

Cytochalasin P1, a new cytochalasin from the marine-derived fungus Xylaria sp. SOF11

2017 ◽  
Vol 72 (3-4) ◽  
pp. 129-132 ◽  
Author(s):  
Ziming Chen ◽  
Yuchan Chen ◽  
Hongbo Huang ◽  
Hongyan Yang ◽  
Weimin Zhang ◽  
...  
Keyword(s):  
South China Sea ◽  
Tumor Cell ◽  
Cell Lines ◽  
South China ◽  
The South China Sea ◽  
Tumor Cell Lines ◽  
The South ◽  
China Sea ◽  
Data Analyses ◽  
Mcf 7

Abstract A new cytochalasin, named cytochalasin P1 (1), together with four known analogs (2–5) was isolated from marine-derived fungus Xylaria sp. SOF11 from the South China Sea. The structure of the new compound was elucidated on the basis of MS and NMR (1H, 13C, HSQC, HMBC, and NOESY) data analyses. Compounds 1–5 were tested for their cytotoxicities against four tumor cell lines (SF-268, MCF-7, NCI-H460, and HepG-2). Compounds 1–5 showed significant cytotoxicity against two tumor cell lines MCF-7 and SF-268, with the IC50 values varying between 0.33 and 4.17 μM.

scholarly journals Chemical Constituents of the Soft Coral Sarcophyton Infundibuliforme from the South China Sea

2010 ◽  
Vol 5 (8) ◽  
pp. 1934578X1000500 ◽  
Author(s):  
Xue-Ping Sun ◽  
Chang-Yun Wang ◽  
Chang-Lun Shao ◽  
Liang Li ◽  
Xiu-Bao Li ◽  
...  
Keyword(s):  
South China Sea ◽  
South China ◽  
Soft Coral ◽  
Chemical Constituents ◽  
2D Nmr ◽  
Comprehensive Analysis ◽  
The South China Sea ◽  
The South ◽  
China Sea ◽  
2D Nmr Spectra

One new cembrane diterpenoid, named sarcolactone A (1), along with five known compounds (2–6) were isolated from the soft coral Sarcophyton infundibuliforme collected from the South China Sea. The structure of sarcolactone A (1) was elucidated by comprehensive analysis of spectral data, especially 2D-NMR spectra (1H-1H COSY, HMBC and NOESY). All the compounds were evaluated for their brine shrimp lethality and antifouling activities.

Three Polyoxygenated Steroids from the South China Sea Gorgonian Coral Subergorgia reticulata

ChemInform ◽  
2006 ◽  
Vol 37 (1) ◽  
Author(s):  
Jin Yang ◽  
Shu-Hua Qi ◽  
Si Zhang ◽  
Jun Wu ◽  
Zhi-Hui Xiao
Keyword(s):  
South China Sea ◽  
South China ◽  
The South China Sea ◽  
The South ◽  
Gorgonian Coral ◽  
China Sea

Steroids from the South China Sea Gorgonian Coral Muricella flexuosa

2011 ◽  
Vol 66 ◽  
pp. 0635 ◽  
Author(s):  
P. Wang ◽  
S.-H. Qi ◽  
K.-S. Liu ◽  
L.-S. Huang ◽  
F. He ◽  
...  
Keyword(s):  
South China Sea ◽  
South China ◽  
The South China Sea ◽  
The South ◽  
Gorgonian Coral ◽  
China Sea

9,11-Secosteroids with cytotoxic activity from the South China Sea gorgonian coral Subergorgia suberosa

Steroids ◽  
2015 ◽  
Vol 98 ◽  
pp. 100-106 ◽  
Author(s):  
Jun Zhang ◽  
Ling-Li Liu ◽  
Ba-Lian Zhong ◽  
Xiao-Jian Liao ◽  
Shi-Hai Xu
Keyword(s):  
South China Sea ◽  
Cytotoxic Activity ◽  
South China ◽  
The South China Sea ◽  
The South ◽  
Gorgonian Coral ◽  
China Sea

Antifouling steroids from the South China Sea gorgonian coral Subergorgia suberosa

Steroids ◽  
2014 ◽  
Vol 79 ◽  
pp. 1-6 ◽  
Author(s):  
Jun Zhang ◽  
Yan Liang ◽  
Kai-Ling Wang ◽  
Xiao-Jian Liao ◽  
Zhou Deng ◽  
...  
Keyword(s):  
South China Sea ◽  
South China ◽  
The South China Sea ◽  
The South ◽  
Gorgonian Coral ◽  
China Sea

scholarly journals Briarane Diterpenes from the South China Sea Gorgonian Coral, Junceella gemmacea

Marine Drugs ◽  
2014 ◽  
Vol 12 (2) ◽  
pp. 589-600 ◽  
Author(s):  
Wei Zhou ◽  
Jiao Li ◽  
Heng-Chao E ◽  
Bao-Shu Liu ◽  
Hua Tang ◽  
...  
Keyword(s):  
South China Sea ◽  
South China ◽  
The South China Sea ◽  
The South ◽  
Gorgonian Coral ◽  
China Sea
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