Novel inhibitors of signal transducer and activator of transcription 3 signaling pathway: an update on the recent patent literature

Expert Opinion on Therapeutic Patents ◽

10.1517/13543776.2014.877443 ◽

2014 ◽

Vol 24 (4) ◽

pp. 383-400 ◽

Author(s):

Antonio Lavecchia ◽

Carmen Di Giovanni ◽

Carmen Cerchia

Keyword(s):

Signaling Pathway ◽

Signal Transducer ◽

Patent Literature ◽

Transcription 3

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Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113333 ◽

2021 ◽

Vol 216 ◽

pp. 113333

Author(s):

Dingding Gao ◽

Nan Jin ◽

Yixian Fu ◽

Yueyue Zhu ◽

Yujie Wang ◽

...

Keyword(s):

Drug Design ◽

Signaling Pathway ◽

Rational Drug Design ◽

Signal Transducer ◽

Stat3 Signaling ◽

Stat3 Signaling Pathway ◽

Rational Drug ◽

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Qingnaoyizhi decoction suppresses the formation of glial fibrillary acidic protein-positive cells in cultured neural stem cells by inhibiting the Janus kinase 2 / signal transducer and activator of transcription 3 signaling pathway

Journal of Traditional Chinese Medicine ◽

10.1016/s0254-6272(15)30011-x ◽

2015 ◽

Vol 35 (1) ◽

pp. 69-76 ◽

Author(s):

Wu Yanqing ◽

Jing Zhiwei ◽

Qin Xiude ◽

Zhou Zhen ◽

Wang Kai ◽

...

Keyword(s):

Glial Fibrillary Acidic Protein ◽

Neural Stem Cells ◽

Signaling Pathway ◽

Janus Kinase ◽

Acidic Protein ◽

Signal Transducer ◽

Janus Kinase 2 ◽

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Inhibition of the Signal Transducer and Activator of Transcription-3 (STAT3) Signaling Pathway by 4-Oxo-1-Phenyl-1,4-Dihydroquinoline-3-Carboxylic Acid Esters

Journal of Medicinal Chemistry ◽

10.1021/jm701271y ◽

2008 ◽

Vol 51 (14) ◽

pp. 4115-4121 ◽

Author(s):

Jun Xu ◽

Derek C. Cole ◽

Chao-Pei Betty Chang ◽

Ramzi Ayyad ◽

Magda Asselin ◽

...

Keyword(s):

Carboxylic Acid ◽

Signaling Pathway ◽

Signal Transducer ◽

Stat3 Signaling ◽

Stat3 Signaling Pathway ◽

Transcription 3 ◽

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Maslinic acid suppresses the growth of human gastric cells by inducing apoptosis via inhibition of the interleukin-6 mediated Janus kinase/signal transducer and activator of transcription 3 signaling pathway

Oncology Letters ◽

10.3892/ol.2017.6073 ◽

2017 ◽

Vol 13 (6) ◽

pp. 4875-4881 ◽

Author(s):

Deyou Wang ◽

Sifeng Tang ◽

Qiwen Zhang

Keyword(s):

Signaling Pathway ◽

Interleukin 6 ◽

Janus Kinase ◽

Signal Transducer ◽

Maslinic Acid ◽

Gastric Cells ◽

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Non-coding RNA 886 promotes renal cell carcinoma growth and metastasis through the Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway

Molecular Medicine Reports ◽

10.3892/mmr.2017.7093 ◽

2017 ◽

Vol 16 (4) ◽

pp. 4273-4278 ◽

Author(s):

Jun Lei ◽

Ju-Hua Xiao ◽

Shou-Hua Zhang ◽

Zhi-Qiang Liu ◽

Kai Huang ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

Cell Carcinoma ◽

Signaling Pathway ◽

Janus Kinase ◽

Signal Transducer ◽

Janus Kinase 2 ◽

Non Coding Rna ◽

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Inhibition of the signal transducer and activator of transcription 3 signaling pathway by Qianliening capsules suppresses the growth and induces the apoptosis of human prostate cells

Molecular Medicine Reports ◽

10.3892/mmr.2014.2946 ◽

2014 ◽

Vol 11 (3) ◽

pp. 2207-2214 ◽

Author(s):

JIUMAO LIN ◽

JIANHENG ZHOU ◽

XIAOYONG ZHONG ◽

ZHENFENG HONG ◽

JUN PENG

Keyword(s):

Signaling Pathway ◽

Human Prostate ◽

Signal Transducer ◽

Prostate Cells ◽

Transcription 3

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Levetiracetam Reduces Early Inflammatory Response After Experimental Intracerebral Hemorrhage by Regulating the Janus Kinase 2 (JAK2)–Signal Transducer and Activator of Transcription 3 (STAT3) Signaling Pathway

Medical Science Monitor ◽

10.12659/msm.922741 ◽

2020 ◽

Vol 26 ◽

Author(s):

Jing Xiong ◽

Han Zhou ◽

Donglin Lu ◽

Zixuan Wang ◽

HengJian Liu ◽

...

Keyword(s):

Inflammatory Response ◽

Intracerebral Hemorrhage ◽

Signaling Pathway ◽

Janus Kinase ◽

Signal Transducer ◽

Janus Kinase 2 ◽

Stat3 Signaling ◽

Stat3 Signaling Pathway ◽

Early Inflammatory Response ◽

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High mobility group box 1 induces the activation of the Janus kinase 2 and signal transducer and activator of transcription 3 (JAK2/STAT3) signaling pathway in pancreatic acinar cells in rats, while AG490 and rapamycin inhibit their activation

Bosnian Journal of Basic Medical Sciences ◽

10.17305/bjbms.2016.1442 ◽

2016 ◽

Author(s):

Guoliang Wang ◽

Jingchao Zhang ◽

Danhua Dui ◽

Haoyuan Ren ◽

Jin Liu

Keyword(s):

Signaling Pathway ◽

High Mobility ◽

Acinar Cells ◽

Janus Kinase ◽

High Mobility Group ◽

Pancreatic Acinar Cells ◽

Signal Transducer ◽

Stat3 Signaling ◽

Stat3 Signaling Pathway ◽

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Radiation Inhibits Interleukin-12 Production via Inhibition of C-Rel through the Interleukin-6/ Signal Transducer and Activator of Transcription 3 Signaling Pathway in Dendritic Cells

PLoS ONE ◽

10.1371/journal.pone.0146463 ◽

2016 ◽

Vol 11 (1) ◽

pp. e0146463 ◽

Author(s):

Eun-Jung Lee ◽

Seo Jin Lee ◽

Ji-Hye Kim ◽

Kyoung-Jin Kim ◽

Seung-Hyun Yang ◽

...

Keyword(s):

Dendritic Cells ◽

Signaling Pathway ◽

Interleukin 6 ◽

Interleukin 12 ◽

Signal Transducer ◽

Transcription 3

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Hydrogen‑rich solution attenuates myocardial injury caused by cardiopulmonary bypass in rats via the Janus‑activated kinase 2/signal transducer and activator of transcription 3 signaling pathway

Oncology Letters ◽

10.3892/ol.2018.8639 ◽

2018 ◽

Author(s):

Keyan Chen ◽

Yingjie Sun ◽

Yugang Diao ◽

Tiezheng Zhang ◽

Wanwei Dong

Keyword(s):

Cardiopulmonary Bypass ◽

Signaling Pathway ◽

Myocardial Injury ◽

Signal Transducer ◽

Rich Solution ◽

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