Optimization of the decision threshold for single radioactive counting

2007 ◽  
Vol 95 (8) ◽  
Author(s):  
V. Vivier ◽  
Jean Aupiais

When the activity of a sample is close to the background level, the decision threshold is classically defined by considering distributions of sample and background as being equal. Recently, the Bayesian approach has been considered in the standard ISO to refine the determination of the decision threshold by taking into account all accessible information prior to measurement such as type A and type B uncertainties. However, simplifications using Gaussian approximation and experimental values instead of true means are often used to facilitate calculations. In this paper, we develop a complete treatment without simplification, based on the Bayesian approach and Poisson distribution. Minimal informations have been considered: one single raw counting for the sample and one previously acquired background. From one single background counting, the net background probability law is calculated and then a decision threshold is deduced. In particular, we demonstrate that the decision threshold is defined for any case including very low background or even null event. Comparisons with classical approach as well as the Bayesian treatment in the new ISO 11929 have been carried out. Applications of this decision threshold for the optimisation of radioactive measurement or in case of a set of minimal detectable activities used to determine average releases are given. Bayesian treatment also gives relevant informations such as the probability for a source to be radioactive when the net number of counts is below the decision threshold.

2010 ◽  
Vol 98 (6) ◽  
Author(s):  
Jean Aupiais ◽  
V. Vivier

AbstractRecently, the Bayesian approach has been considered in the standard ISO to refine the determination of the decision threshold by taking into account all accessible information such as type A and type B uncertainties. In a previous paper [1] and later a corrigendum [2], we had demonstrated that such treatment was not properly performed and we have developed a complete treatment without simplification, based on the Bayesian approach and Poisson distribution. A new law of distribution of the net counting knowing one experimental determination of the background was thus introduced. Here, we discuss the comments from S. Sterlinski about this law of distribution. All variables in bold and italic are random while all variables in italic style are numbers experimentally obtained after a measurement.


2021 ◽  
Vol 14 (2) ◽  
pp. 231-232
Author(s):  
Adnan Kastrati ◽  
Alexander Hapfelmeier

Author(s):  
Daiane Aparecida Zuanetti ◽  
Luis Aparecido Milan

In this paper, we propose a new Bayesian approach for QTL mapping of family data. The main purpose is to model a phenotype as a function of QTLs’ effects. The model considers the detailed familiar dependence and it does not rely on random effects. It combines the probability for Mendelian inheritance of parents’ genotype and the correlation between flanking markers and QTLs. This is an advance when compared with models which use only Mendelian segregation or only the correlation between markers and QTLs to estimate transmission probabilities. We use the Bayesian approach to estimate the number of QTLs, their location and the additive and dominance effects. We compare the performance of the proposed method with variance component and LASSO models using simulated and GAW17 data sets. Under tested conditions, the proposed method outperforms other methods in aspects such as estimating the number of QTLs, the accuracy of the QTLs’ position and the estimate of their effects. The results of the application of the proposed method to data sets exceeded all of our expectations.


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