The N.C.A. criteria for the diagnosis of alcoholism; an empirical evaluation study.

AbstractMutational signatures refer to patterns in the occurrence of somatic mutations that reflect underlying mutational processes. To date, after the analysis of tens of thousands of genomes and exomes from about 40 different cancers types, 30 mutational signatures characterized by a unique probability profile across the 96 mutation types have been identified, validated and listed on the COSMIC (Catalogue of Somatic Mutations in Cancer) website. Simultaneously with this development, the last few years saw the publication of several concurrent methods (mathematical algorithms implemented in publicly available software packages) for either the quantification of the contribution of prespecified signatures (e.g. COSMIC signatures) in a given cancer genome or the identification of new signatures from a sample of cancer genomes. A review about existing computational tools has been recently published to guide researchers and practitioners in conducting their mutational signatures analysis, however, other tools have been introduced since its publication and, to date, there has not been a systematic evaluation and comparison of the performance of such tools. In order to fill this gap, we carry on an empirical evaluation study of all available packages to date, using both real and simulated data.

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An Empirical Performance Evaluation of Multiple Intel Optane Solid-State Drives

Electronics ◽

10.3390/electronics10111325 ◽

2021 ◽

Vol 10 (11) ◽

pp. 1325

Author(s):

Jaehyun Han ◽

Guangyu Zhu ◽

Sangmook Lee ◽

Yongseok Son

Keyword(s):

Cloud Computing ◽

Solid State ◽

Performance Metrics ◽

Empirical Evaluation ◽

Evaluation Study ◽

Cloud Services ◽

Experimental Results ◽

Solid State Drives ◽

Non Volatile Memory ◽

And Performance

Cloud computing as a service-on-demand architecture has grown in importance over the last few years. The storage subsystem in cloud computing has undergone enormous innovation to provide high-quality cloud services. Emerging Non-Volatile Memory Express (NVMe) technology has attracted considerable attention in cloud computing by delivering high I/O performance in latency and bandwidth. Specifically, multiple NVMe solid-state drives (SSDs) can provide higher performance, fault tolerance, and storage capacity in the cloud computing environment. In this paper, we performed an empirical evaluation study of performance on recent NVMe SSDs (i.e., Intel Optane SSDs) with different redundant array of independent disks (RAID) environments. We analyzed multiple NVMe SSDs with RAID in terms of different performance metrics via synthesis and database benchmarks. We anticipate that our experimental results and performance analysis will have implications for various storage systems. Experimental results showed that the software stack overhead reduced the performance by up to 75%, 52%, 76%, 91%, and 92% in RAID 0, 1, 10, 5, and 6, respectively, compared with theoretical and expected performance.

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The Effectiveness of Lutheran Elementary and Secondary Schools as Agencies of Christian Education: An Empirical Evaluation Study of the Impact of Lutheran Parochial Schools on the Beliefs, Attitudes, and Behavior of Lutheran Youth

Review of Religious Research ◽

10.2307/3510912 ◽

1969 ◽

Vol 10 (2) ◽

pp. 112

Author(s):

Kenneth Stokes ◽

Ronald L. Johnstone

Keyword(s):

Secondary Schools ◽

Christian Education ◽

Empirical Evaluation ◽

Evaluation Study ◽

Parochial Schools ◽

And Behavior ◽

Attitudes And Behavior ◽

The Impact

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The Misconceptions About Multimedia Learning Questionnaire: An Empirical Evaluation Study With Teachers and Student Teachers

Psychology Learning & Teaching ◽

10.1177/14757257211028723 ◽

2021 ◽

pp. 147572572110287

Author(s):

Alexander Eitel ◽

Anja Prinz ◽

Julia Kollmer ◽

Lea Niessen ◽

Jessica Russow ◽

...

Keyword(s):

Teacher Education ◽

Learning Styles ◽

Student Teachers ◽

Multimedia Learning ◽

A Priori ◽

Empirical Evaluation ◽

Evaluation Study ◽

Multimedia Instruction ◽

Hemispheric Communication ◽

And Training

In this study, we present the newly developed Misconceptions about Multimedia Learning Questionnaire (MMLQ), we evaluate its psychometric properties (item difficulties, scale reliabilities, and internal structure), and we use it to examine the prevalence of four different misconceptions about multimedia learning in student teachers and teachers. A total of 311 participants (176 teachers and 135 student teachers) responded to the items of the MMLQ. The results revealed moderate reliabilities of the MMLQ scales. Moreover, an a priori assumed four-factor structure of misconceptions about multimedia learning was most compatible with teachers’ and student teachers’ answers to the MMLQ items. These four factors were learning styles (multimedia instruction needs to be adapted to students’ learning styles [visual or auditory]), hemispheric isolation (multimedia instruction enables hemispheric communication), naïve summation (multimedia instruction is more effective the more sensory channels are used), and motivation primacy (multimedia instruction is mainly effective because it is motivating). The majority of teachers and student teachers endorsed three of the four misconceptions about multimedia learning (i.e., learning styles [78.1%], hemispheric isolation [58.8%], and naïve summation [81.4%]) as assessed by the MMLQ. This finding may provide valuable information for teacher education and training regarding this specific issue.

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