Effective therapeutic control of curve progression using calcium and vitamin D supplementation for adolescent idiopathic scoliosis - a randomized double-blinded placebo-controlled trial

2017 ◽  
Author(s):  
Tsz Ping Lam ◽  
Benjamin Hon Kei Yip ◽  
Gene Chi Wai Man ◽  
Wayne YW Lee ◽  
Elisa Man Shan Tam ◽  
...  
Keyword(s):  
Vitamin D ◽  
Adolescent Idiopathic Scoliosis ◽  
Idiopathic Scoliosis ◽  
Controlled Trial ◽  
Vitamin D Supplementation ◽  
Curve Progression ◽  
Therapeutic Control ◽  
Double Blinded

scholarly journals The effects of vitamin D supplementation on adiponectin level and insulin resistance in first-degree relatives of subjects with type 2 diabetes: a randomized double-blinded controlled trial

10.19082/2849 ◽  
2016 ◽  
Vol 8 (9) ◽  
pp. 2849-2854 ◽  
Author(s):  
Seyed Mohammad Mohammadi ◽  
Seyed Ahmad Eghbali ◽  
Sedighah Soheilikhah ◽  
Saeedeh Jam Ashkezari ◽  
Maryam Salami ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Adiponectin Level ◽  
Controlled Trial ◽  
Vitamin D Supplementation ◽  
First Degree Relatives ◽  
Double Blinded

Short-term Effects of Calcium and Vitamin D Supplementation in Postmenopausal Hypertensive Patients in sub-Saharan Africa: A Double Blinded Randomized Controlled Trial

2021 ◽  
Vol 1 (3) ◽  
pp. 59-64
Author(s):  
Chris Nadège Nganou-Gnindjio ◽  
Vicky Jocelyne Ama Moor ◽  
Constant Anatole Pieme ◽  
Guy Sadeu Wafeu ◽  
Ingrid Ngandjeu Kamtchoum ◽  
...  
Keyword(s):  
Vitamin D ◽  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Vitamin D Supplementation ◽  
Sub Saharan Africa ◽  
Short Term ◽  
Hypertensive Patients ◽  
Randomized Controlled ◽  
Sub Saharan ◽  
Double Blinded

scholarly journals Effects of Genetic and Nongenetic Factors on Total and Bioavailable 25(OH)D Responses to Vitamin D Supplementation

2016 ◽  
Vol 102 (1) ◽  
pp. 100-110 ◽  
Author(s):  
Pang Yao ◽  
Liang Sun ◽  
Ling Lu ◽  
Hong Ding ◽  
Xiafei Chen ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Vitamin D3 ◽  
Controlled Trial ◽  
Vitamin D Supplementation ◽  
Inverse Association ◽  
Vitamin D Metabolism ◽  
Hydroxyvitamin D ◽  
Vitamin D3 Supplementation ◽  
Double Blinded

Abstract Context: Little is known about how genetic and nongenetic factors modify responses of vitamin D supplementation in nonwhite populations. Objective: To investigate factors modifying 25-hydroxyvitamin D [25(OH)D] and bioavailable 25(OH)D [25(OH)DBio] responses after vitamin D3 supplementation. Design, Setting, Participants, and Intervention: In this 20-week, randomized, double-blinded, placebo-controlled trial, 448 Chinese with vitamin D deficiency received 2000 IU/d vitamin D3 or placebo. Main Outcome Measures: Serum 25(OH)D, vitamin D-binding protein (VDBP), parathyroid hormone (PTH) and calcium were measured, and 25(OH)DBio was calculated based on VDBP levels. Six common polymorphisms in vitamin D metabolism genes were genotyped. Results: Between-arm net changes were +30.6 ± 1.7 nmol/L for 25(OH)D, +2.7 ± 0.2 nmol/L for 25(OH)DBio, and −5.2 ± 1.2 pg/mL for PTH, corresponding to 70% [95% confidence interval (CI), 62.8% to 77.2%] net reversion rate for vitamin D deficiency at week 20 (P < 0.001). Only 25(OH)DBio change was positively associated with calcium change (P < 0.001). Genetic factors (GC-rs4588/GC-rs7041, VDR-rs2228570, and CYP2R1-rs10741657; P ≤ 0.04) showed stronger influences on 25(OH)D or 25(OH)DBio responses than nongenetic factors, including baseline value, body mass index, and sex. An inverse association of PTH-25(OH)D was demonstrated only at 25(OH)D of <50.8 (95% CI, 43.6 to 59.0) nmol/L. Conclusions: Supplemented 2000 IU/d vitamin D3 raised 25(OH)D and 25(OH)DBio but was unable to correct deficiency in 25% of Chinese participants, which might be partially attributed to the effect of genetic modification. More studies are needed to elucidate appropriate vitamin D recommendations for Asians and the potential clinical implications of 25(OH)DBio.

scholarly journals Effect of Vitamin D Supplementation on Intracytoplasmic Sperm Injection Outcomes: A Randomized Double-Blinded Placebo-Controlled Trial

2018 ◽  
Vol 08 (14) ◽  
pp. 1549-1556 ◽  
Author(s):  
Ahmed H. Abd-Ellah ◽  
Abd El-Naser Abd El-Gaber Ali ◽  
Mustafa M. Khodry ◽  
Mahmoud I. El-Rasheedy ◽  
Ahmed M. Abbas
Keyword(s):  
Vitamin D ◽  
Intracytoplasmic Sperm Injection ◽  
Controlled Trial ◽  
Vitamin D Supplementation ◽  
Double Blinded

Vibration treatment can enhance the bioactive response of osteoblasts to vitamin D in adolescent idiopathic scoliosis patients

2015 ◽  
Author(s):  
Jiajun Zhang ◽  
WayneY W Lee ◽  
Benlong Shi ◽  
Elisa M S Tam ◽  
Huanxiong Chen ◽  
...  
Keyword(s):  
Vitamin D ◽  
Adolescent Idiopathic Scoliosis ◽  
Idiopathic Scoliosis ◽  
Vibration Treatment

Effect of Vitamin D supplementation on body composition in overweight men: A randomized controlled trial

2017 ◽  
Author(s):  
Christos Karefylakis ◽  
Annaclara Ariander ◽  
Stefan Sarnblad ◽  
Peter Rask ◽  
Eva Rask
Keyword(s):  
Vitamin D ◽  
Randomized Controlled Trial ◽  
Body Composition ◽  
Controlled Trial ◽  
Vitamin D Supplementation ◽  
Randomized Controlled
Sign in / Sign up

Export Citation Format

Share Document