Radiation-induced multiple late complications after childhood acute lymphoblastic leukemia: A case report

2014 ◽  
Author(s):  
Cecilia Follin ◽  
Eva Marie Erfurth
Keyword(s):  
Case Report ◽  
Acute Lymphoblastic Leukemia ◽  
Lymphoblastic Leukemia ◽  
Late Complications ◽  
Childhood Acute Lymphoblastic Leukemia ◽  
Radiation Induced

scholarly journals Intrachromosomal amplification of chromosome 21 (iAMP21) detected by ETV6/RUNX1 FISH screening in childhood acute lymphoblastic leukemia: a case report

2013 ◽  
Vol 35 (5) ◽  
Author(s):  
Daniela Ribeiro Ney Garcia ◽  
Alejandro Mauricio Arancibia ◽  
Raul C. Ribeiro ◽  
Marcelo Gerardin Poirot Land ◽  
Maria Luiza Macedo Silva
Keyword(s):  
Case Report ◽  
Acute Lymphoblastic Leukemia ◽  
Lymphoblastic Leukemia ◽  
Chromosome 21 ◽  
Childhood Acute Lymphoblastic Leukemia

Recurrence of Childhood Acute Lymphoblastic Leukemia Presenting as a Tumor of the Middle Ear: A Case Report

1997 ◽  
Vol 19 (4) ◽  
pp. 351-353 ◽  
Author(s):  
Frédéric Millot ◽  
Jean Michel Klossek ◽  
Françoise Brizard ◽  
André Brizard ◽  
Pierre Vandermarq ◽  
...  
Keyword(s):  
Case Report ◽  
Acute Lymphoblastic Leukemia ◽  
Middle Ear ◽  
Lymphoblastic Leukemia ◽  
Childhood Acute Lymphoblastic Leukemia

Second malignancies in patients treated for childhood acute lymphoblastic leukemia.

1998 ◽  
Vol 16 (8) ◽  
pp. 2848-2853 ◽  
Author(s):  
V M Kimball Dalton ◽  
R D Gelber ◽  
F Li ◽  
M J Donnelly ◽  
N J Tarbell ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Confidence Interval ◽  
Radiation Field ◽  
Lymphoblastic Leukemia ◽  
Epithelioid Sarcoma ◽  
Late Complications ◽  
Childhood Acute Lymphoblastic Leukemia ◽  
Malignant Neoplasms ◽  
Childhood All ◽  
Induction Failure

PURPOSE Second malignant neoplasms (SMN) are devastating late complications of childhood acute lymphoblastic leukemia (ALL) and its treatment. We evaluated the incidence and type of SMN diagnosed before leukemic relapse in a large series of patients with ALL. PATIENTS AND METHODS We reviewed the outcome of all patients treated for childhood ALL between 1972 and 1995 on Dana-Farber Cancer Institute (DFCI) and DFCI ALL Consortium protocols. The follow-up time from diagnosis of ALL to induction failure, relapse, remission death, or SMN, whichever occurred first, ranged from 0 to 24.0 years (median, 7.6 years; mean, 6.7 years). RESULTS Thirteen SMNs were diagnosed among 1,597 patients. Eight tumors occurred in a radiation field (five in the CNS and three in the head and neck), two occurred outside of a radiation field (one adenocarcinoma of the sigmoid colon and one epithelioid sarcoma of the chest wall), and three were hematopoietic malignancies. The median time to occurrence was 6.7 years (range, 1.0 to 17.2 years) and the cumulative incidence of second malignancy before another first event was 2.7% (95% confidence interval, 0.7 to 4.7). The risk of a first event, which included induction failure, relapse, or remission death, was 31.0% (95% confidence interval, 28.5 to 33.5). CONCLUSION We found a more than 10-fold risk of other first events when compared with SMN. Thus, we conclude that SMN before first relapse is a relatively uncommon occurrence among survivors of childhood ALL. Future therapeutic regimens must focus on reducing leukemia relapse and enhancing quality of life, as well as preventing SMNs.

scholarly journals Successful pregnancies after transplantation of ovarian tissue retrieved and cryopreserved at time of childhood acute lymphoblastic leukemia – A case report

Haematologica ◽  
2021 ◽  
Author(s):  
Kenny A. Rodriguez-Wallberg ◽  
Milan Milenkovic ◽  
Kiriaki Papaikonomou ◽  
Victoria Keros ◽  
Britt Gustafsson ◽  
...  
Keyword(s):  
Case Report ◽  
Acute Lymphoblastic Leukemia ◽  
Lymphoblastic Leukemia ◽  
Ovarian Tissue ◽  
Childhood Acute Lymphoblastic Leukemia

Not available.

Genetic characterization of high hyperdiploidy in childhood acute lymphoblastic leukemia

2009 ◽  
Vol 221 (03) ◽  
Author(s):  
R Vagkopoulou ◽  
C Eckert ◽  
U Ungethüm ◽  
G Körner ◽  
M Stanulla ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Genetic Characterization ◽  
Lymphoblastic Leukemia ◽  
Childhood Acute Lymphoblastic Leukemia
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