scholarly journals Comparison of Microplegia Solution and Del Nido Cardioplegia Solution in Coronary Artery Bypass Grafting Surgery: Which One is More Effective?

2021 ◽  
Vol 24 (5) ◽  
pp. E842-E848
Author(s):  
Yusuf Salim Urcun ◽  
Arda Aybars Pala
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass ◽  
Coronary Artery Bypass Surgery ◽  
Bypass Surgery ◽  
Artery Bypass ◽  
Ventricular Ejection Fraction ◽  
Cardioplegia Solution ◽  
Cross Clamp Time ◽  
Extubation Time ◽  
Significant Difference

Background: The aim of this study is to compare the efficacy of the microplegia solution and Del Nido cardioplegia solution in coronary artery bypass surgery with clinical, biochemical, and echocardiographic data. Methods: Three hundred patients, who underwent coronary artery bypass surgery between January 2017 and January 2020, by the same surgical team were included in the study. Preoperative, operative and postoperative data (cardiac biomarker levels, cross-clamp and CPB times, echocardiographic measurements, etc.) of the patients were compared. Results: In the study, cross-clamp time was significantly shorter in the DN cardioplegia group (55.60 ± 13.49 min/75.58 ± 12.43 min, P = 0.024). No significant difference was observed between the two groups in terms of intensive care stay, extubation time, hospital stay, and cardiopulmonary bypass time. In our study, it was shown that both the left and right ventricular ejection fraction was better protected in the Del Nido cardioplegia group (5.34±3.03 vs. 3.40±2.84, P = 0.017 and 3.82±1.19 vs. 2.28±1.87, P = 0.047, respectively), and the need for inotrope support was lower in this group (28% vs. 44%, P < 0.021). There was no significant difference between the groups, in terms of blood transfusion rates, IABP requirement. Conclusion: In light of short-term results, we can say that Del Nido cardioplegia provides better myocardial protection than microplegia. In addition, Del Nido cardioplegia can be given as a single dose for 90 minutes of cross-clamp time and therefore can be preferred to increase surgical comfort and reduce cross-clamp times.

scholarly journals The importance of del nido cardioplegia solution in coronary artery bypass surgery

2021 ◽  
Vol 36 (4) ◽  
pp. 1575-1575
Author(s):  
Mehmet S. Bademci ◽  
Cemal Kocaaslan ◽  
Fatih A. Bayraktar ◽  
Ahmet Oztekin ◽  
Huseyin B. Aydin ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass ◽  
Coronary Artery Bypass Surgery ◽  
Bypass Surgery ◽  
Artery Bypass ◽  
Cardioplegia Solution

Abstract 3040: Coronary Artery Bypass Surgery In 14,956 Patients With Cardiogenic Shock: The Society Of Thoracic Surgeons National Database Experience

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Rajendra H Mehta ◽  
Joshua D Grab ◽  
Sean M O’Brien ◽  
Donald D Glower ◽  
Jeffrey P Jacobs ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Cardiogenic Shock ◽  
Coronary Artery Bypass ◽  
Coronary Artery Bypass Surgery ◽  
Bypass Surgery ◽  
Artery Bypass ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
National Database ◽  
Ventricular Ejection Fraction

Background . While only a small minority of patients undergo coronary artery bypass surgery (CABG) in the setting of cardiogenic shock (CS), these patients face a high risk for mortality and morbidity. There exist few studies that characterize clinical features and outcomes in CS patients undergoing CABG in contemporary community practice. Methods . We evaluated data of 14,956 patients with CS in comparison with 693637 without CS undergoing CABG between 2002 and 2005 at hospitals participating in the Society of Thoracic Surgeons National Database. Clinical, angiographic and operative features and in-hospital outcomes were studied in patients with and without CS. Results . Patients with preoperative CS constituted 2.1% of patients undergoing CABG yet accounted for 16% of all CABG deaths. These patients had greater comorbid conditions and left main disease and lower left ventricular ejection fraction. In-hospital events and length of hospital stay (median 96 vs. 36 days) were significantly higher in CS patients. Operative mortality was high (rising from 20% for isolated CABG, to 33% for CABG+ valve surgery, to 58% for CABG+ ventricular septal repair). While mortality for CABG surgery overall has declined significantly overtime (p for trend< .0001), mortality for CS patients have not changed significantly over the 4 year study period (p= .07, Figure ). Conclusions . Patients with CS represents minority of patients undergoing CABG, yet with persistently high operative risks. These patients in fact account for 1 of every 7 deaths in patients undergoing CABG. Ongoing efforts are warranted to continuously develop and evaluate new strategies to improve outcomes of these patients.

scholarly journals The importance of del nido cardioplegia solution in coronary artery bypass surgery

2020 ◽  
Author(s):  
Mehmet Bademci ◽  
Cemal Kocaaslan ◽  
Fatih Bayraktar ◽  
Ahmet Oztekin ◽  
Bilal Aydin ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass ◽  
Coronary Artery Bypass Surgery ◽  
Bypass Surgery ◽  
Artery Bypass ◽  
Cardioplegia Solution

Effect of magnesium sulfate on extubation time and acute pain in coronary artery bypass surgery

2008 ◽  
Vol 52 (10) ◽  
pp. 1348-1352 ◽  
Author(s):  
R. FERASATKISH ◽  
A. DABBAGH ◽  
M. ALAVI ◽  
G. MOLLASADEGHI ◽  
E. HYDARPUR ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Magnesium Sulfate ◽  
Coronary Artery Bypass ◽  
Acute Pain ◽  
Coronary Artery Bypass Surgery ◽  
Bypass Surgery ◽  
Artery Bypass ◽  
Extubation Time

scholarly journals A Comparison of Patients Undergoing On- vs. Off-Pump Coronary Artery Bypass Surgery Managed with a Fast-Track Protocol

2021 ◽  
Vol 10 (19) ◽  
pp. 4470
Author(s):  
Henrike Grützner ◽  
Anna Flo Forner ◽  
Massimiliano Meineri ◽  
Aniruddha Janai ◽  
Jörg Ender ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass ◽  
Coronary Artery Bypass Surgery ◽  
Fast Track ◽  
Bypass Surgery ◽  
Artery Bypass ◽  
Post Anesthesia Care Unit ◽  
Off Pump ◽  
Significant Difference ◽  
Pump Coronary Artery Bypass

The purpose of this study was to compare patients who underwent on- vs. off-pump coronary artery bypass surgery managed with a fast-track protocol. Between September 2012 and December 2018, n = 3505 coronary artery bypass surgeries were managed with a fast-track protocol in our specialized post-anesthesia care unit. Propensity score matching was applied and resulted in two equal groups of n = 926. There was no significant difference in ventilation time (on-pump 75 (55–120) min vs. off-pump 80 (55–120) min, p = 0.973). We found no statistically significant difference in primary fast-track failure in on-pump (8.2% (76)) vs. off-pump (6% (56)) groups (p = 0.702). The secondary fast-track failure rate was comparable (on-pump 12.9% (110) vs. off-pump 12.3% (107), p = 0.702). There were no significant differences between groups in regard to the post-anesthesia care unit, the intermediate care unit, and the hospital length of stay. Postoperative outcome and complications were also comparable, except for a statistically significant difference in PACU postoperative blood loss in on-pump (234 mL) vs. off-pump (323 mL, p < 0.0001) and red blood cell transfusion (11%) and (5%, p < 0.001), respectively. Our results suggest that on- and off-pump coronary artery bypass surgery in fast-track settings are comparable in terms of ventilation time, fast-track failure rate, and postoperative complications rate.

scholarly journals Novel approaches to the assessment of cardiorespiratory readiness of patients after coronary artery bypass surgery aimed to the efficient cardiac rehabilitation performance

2021 ◽  
Vol 12 (3) ◽  
pp. 139-146
Author(s):  
Tea T. Kakuchaya ◽  
Tamara G. Dzhitava ◽  
Arjanа M. Kuular ◽  
Nona V. Pachuashvili ◽  
Zarina K. Tokaeva
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass ◽  
Coronary Artery Bypass Surgery ◽  
Bypass Surgery ◽  
Training Programs ◽  
Artery Bypass ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Ventricular Ejection Fraction ◽  
Training Activities

Aim. To develop novel strategies of patients selection and risk stratification after coronary artery bypass surgery before starting aerobic cardiorespiratory training programs. Material and methods. One hundred thirty seven patients 4 weeks after coronary artery bypass surgery were included in our study. RARE scale (risk of activity related events), ergospirometric test, FIT treadmill score and certain laboratory parameters like hemoglobin and alaninaminotransferase were used. Results. Logical interdependence is revealed between certain indicators of cardiorespiratory capacity and risk of developing unfavorable events due to aerobic training activities. Comprehensive protocol is developed based on multifactorial regression analysis, which allows to differentiate patients into low and high class of readiness to physical activities, including aerobic cardiorespiratory training programs. Conclusion. The protocol includes following variables METs, RARE scale, FIT treadmill score, left ventricular ejection fraction, hemoglobin and alaninaminotransferase levels. It is very userfriendly, easy, practical and efficient.

scholarly journals Surgical myocardial revascularization using the left internal thoracic artery in patients with diabetes mellitus

2019 ◽  
Vol 10 (1) ◽  
pp. 13-19
Author(s):  
Mikhail V. Gusnay ◽  
Andrey V. Poddubny ◽  
Alexander A. Dyuzhikov
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass ◽  
Coronary Artery Bypass Surgery ◽  
Bypass Surgery ◽  
Artery Bypass ◽  
Myocardial Revascularization ◽  
Lower Class ◽  
Significant Difference ◽  
Patients With Diabetes

Objective:to evaluate the immediate and somewhat distant results of surgical revascularization using the left MKA in patients with diabetes, compared with the results of autovenous CABG, to identify possible complications when using the left MA in patients with diabetes.Materials and methods: 2 groups of patients who, from 2010 to 2012, were selected. performed artery bypass surgery. All patients had type II diabetes. In the first group, the mammaro-coronary artery bypass surgery (MBS) was always used, in the second group and was not performed for various reasons.Results:evaluated indicators aft er 1 year and 6 years. In the immediate postoperative period, we noted a decrease in the class of angina in both groups. We did not observe a significant difference in the violation of the healing of the sternum. In the long-term period, in the group where MBS was performed, we noted a lower mortality rate, a lower class of angina pectoris and a smaller percentage of complications in the cardiovascular system.Conclusions:In patients with multifocal lesions of the coronary bed and concomitant diabetes, the preferred method of coronary artery bypass surgery is MBS, which can be supplemented with CABG. This is confirmed by sixyear observation. MKA can be safely used in diabetes and especially in the stem lesion of the left lance. Problems with the healing of the sternum with careful allocation of LMA we have not noted.

Abstract 233: Cardiac Dysfunction Is Associated with Diminished Cardiac Neuropeptide Expression in Patients Undergoing Coronary Artery Bypass Surgery

2012 ◽  
Vol 111 (suppl_1) ◽  
Author(s):  
Leena Pradhan-Nabzdyk ◽  
Asma Ejaz ◽  
Frank W LoGerfo
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass ◽  
Coronary Artery Bypass Surgery ◽  
Bypass Surgery ◽  
Artery Bypass ◽  
Left Ventricular ◽  
Right Atrial ◽  
Left Ventricular Ejection ◽  
Ventricular Ejection Fraction ◽  
The Relationship

Background: Neuropeptide Y (NPY) and its receptors, NPY1R, NPY2R, and NPY5R, Substance P (SP) and its receptor Neurokinin 1R (NK1R) and calcitonin gene related peptide (CGRP), are important regulators of cardiac physiology, including: vasomodulation, cardiomyocyte hypertrophy, ischemia-induced angiogenesis, modulation of Protein Kinase C activity and calcium homeostasis.[[Unable to Display Character: ]] Objective: To determine the relationship between cardiac function and neuropeptide expression in human subjects. Methods: 38 consecutive patients undergoing elective, on pump, coronary artery bypass surgery (CABG) for coronary artery occlusive disease were studied. A Transesophageal Echo was performed immediately following induction of anesthesia and Left Ventricular Ejection Fraction (LVEF) was determined by AHA criteria as Normal, >55% (NLVEF, n = 26) or Low, <50% (LLVEF, n = 12). Patients with HbA1c>6.0 were considered diabetic. Right atrial tissue was obtained at the time of cannulation and the mRNA expression of Pre-Pro-NPY, NPY1R, NPY2R, NPY5R, Pre-Pro-SP, NK1R and CGRP was determined with qRT-PCR. Data are expressed as fold change relative to the NLVEF group. Results: The results of this study are summarized in the table below. Conclusions: 1. There is a strong association of LLVEF with diminished expression of SP, NK1R and NPY5R, with a similar trend for NPY2R. 2. LLVEF was not associated with HbA1c or diabetes status. 3. The consequences of diminished cardiac neuropeptide expression, the mechanisms involved, the relationship to cardiac autonomic neuropathy, with or without diabetes, warrant priority as an investigational initiative.

scholarly journals Aromatherapy in patients undergoing coronary artery bypass surgery: A systematic review of clinical trials

2021 ◽  
Vol 16 ◽  
pp. 6
Author(s):  
Nasrollah Moradifar ◽  
Mohammad Kalantari Shahijan ◽  
Navid Bakhtiari ◽  
Mojdeh Tavakoli ◽  
Arash Amin
Keyword(s):  
Systematic Review ◽  
Coronary Artery ◽  
Essential Oil ◽  
Coronary Artery Bypass ◽  
Coronary Artery Bypass Surgery ◽  
Bypass Surgery ◽  
Artery Bypass ◽  
Nursing Intervention ◽  
Cabg Surgery ◽  
Extubation Time

In recent years, various investigations have been conducted on the aromatherapy with some essential oils as a non-invasive nursing intervention in various conditions, such as the improvement of anxiety in patients with cardiovascular diseases. The current study aims to systematically review and determine the effects of aromatherapy with various herbs in patients undergoing coronary artery bypass surgery. Five English databases, including Web of Science, Scopus, PubMed, EMBASE, and Google Scholar, were used to find all published clinical papers related to the effects of aromatherapy on the patients with coronary artery bypass surgery without time limitation. All searches were based on the 06- PRISMA guideline and registered in the CAMARADES-NC3Rs Preclinical Systematic Review and Meta-Analysis Facility (SyRF) database. Out of 1835 papers, 13 papers up to 2021, met the inclusion criteria for discussion in this systematic review with the data extracted. The most studies were carried out on effect of aromatherapy on anxiety of patients with coronary artery bypass graft (CABG) surgery (8 papers, 61.5%). The most common used essential oil was belonged to lavender essential oil (11 papers, 84.6%). The findings of the present investigation demonstrated that aromatherapy particularly with lavender is able to significantly decrease anxiety, pain, nausea and vomiting, Sleep quality, Hemodynamic Indices, blood pressure, and extubation time in patients with CABG surgery. However, more studies are required to confirm the accurate mechanisms and side effects of the alternative treatment.

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