Cutaneous pigmentation plays critical role in determining the color of skin along with photo
protection of skin from dreadful effects of ultraviolet radiations. Conversely, abnormal accumulation
of melanin is responsible for hyper pigmentary disorders such as melasma, senile lentigines and freckles.
Because of the visible nature of dermatologic diseases, they have a considerable psychosomatic effect
on affected patients. Tyrosinase inhibitors are molecules that interrelate in some way with the enzyme
to prevent it from working in the normal manner. Past many decades witnessed the quest for the
development of natural tyrosinase inhibitors due to imperative role played by tyrosinase in the process
of melanogenesis and fungi or fruit enzymatic browning. Mechanism of pigmentation is characterized
by the intact process of the synthesis of specialized black pigment within melanosomes. Melanin is
synthesized by a cascade of enzymatic and chemical reactions. For this reason, melanin production is
mainly controlled by the expression and activation of tyrosinase. In the current article, we discussed
tyrosinase inhibitors from the natural sources, which can be an essential constituent of cosmetics products
and depigmenting agents for the treatment of hyperpigmentory disorders.
A multispectral vision system to evaluate enzymatic browning in fresh-cut apple slices