scholarly journals The Contribution of Lumbar Puncture in Neonatal Infections - About 206 cases

2021 ◽  
Vol 8 ◽  
Author(s):  
Ettoini Kaoutar ◽  
Yousra El boussaadni ◽  
Abdallah Oulmaati
Keyword(s):  
High Risk ◽  
Lumbar Puncture ◽  
Clinical Evidence ◽  
Neonatal Infection ◽  
Neonatal Meningitis ◽  
Neonatal Infections ◽  
Pediatric Department ◽  
Serious Infection ◽  
Biological Criteria ◽  
A Prospective Study

Background: Neonatal meningitis is a serious infection, no clinico-biological score has been established to accurately identify neonates at high risk of developing neonatal meningitis.Objective: The aim of this work is to clarify the place of lumbar puncture in neonatal infections and to identify the predictive factors of meningeal localization in case of neonatal infection.Materials and methods: This is a prospective study of 861 observations of newborns hospitalized in the pediatric department of Mohammed V Hospital, CHU of Tangier, during a 14-month period from 1January 2019 to 29 February 2020. Among these patients the diagnosis of neonatal infection (NNI) was retained in 473 cases. Initial lumbar puncture was performed in 206 cases (43%). We included neonates aged 0 to 28 days, suspected of NNI, who had a lumbar puncture. Neonates treated as carriers of neonatal infection without sufficient anamnestic and clinical evidence and with an inconclusive or unperformed biological workup were excluded from the study.Results: During the study period, 861 newborns were hospitalized and the diagnosis of neonatal infection was retained in 473 cases, a rate of 55%, and the initial lumbar puncture was performed in 206 cases (43%). 61 newborns were diagnosed with neonatal meningitis, with fever in 76% of cases, 85% with convulsions, hypotonia and/or refusal to suckle in 63% of cases, and CRP >25mg/l in 67% of newborns.Conclusion: Lumbar puncture is the only diagnostic means of meningitis. Indeed, the indication of this procedure should not be systematic, but it should be dictated by the careful and simultaneous analysis of the anamnestic, clinical and biological criteria evocative of the infection and its meningeal localization in order to diagnose meningitis early and treat it correctly. The need to establish scores combining these different parameters, in order to accurately identify newborns at high risk of developing neonatal meningitis

scholarly journals Early Neonatal Mortality’s Determinants in the Neonatology Department of Mohamed V Hospital in Tangier, Morocco

2021 ◽  
Vol 8 ◽  
Author(s):  
Ettoini Kaoutar ◽  
Yousra El Boussaadni ◽  
Abdallah Oulmaati
Keyword(s):  
Neonatal Mortality ◽  
Perinatal Asphyxia ◽  
Neonatal Infection ◽  
Effective Management ◽  
Third Place ◽  
Pediatric Department ◽  
Early Neonatal Mortality ◽  
Prenatal Consultation ◽  
Education Of Women ◽  
A Prospective Study

Objective: This study aims to identify the determinants of early neonatal mortality in the neonatology department of Mohamed V hospital in Tangier.Material and methods: This is a prospective study including all newborns hospitalized and deceased in the pediatric department of the hospital Mohammed V from June 1 to December 31, 2019. The recorded cases were processed and analyzed by SPSS software.Results: 529 newborns were hospitalized in the pediatric department during the study period, of which 92 died (17.39%) between 0 and 7 days. Four leading causes justified this frequency: prematurity occupies first place (59%), followed by perinatal asphyxia (22%), neonatal infection (15%) in third place, congenital malformations (3%) in fourth place. Parturients aged between 20 and 35 years are the most affected (76%). The majority of women (71.4%) in our series had not undergone prenatal consultation (PNC) or had done so in insufficient numbers.Conclusion: Neonatal mortality remains high. Improvement of this situation requires education of women, reinforcement of surveillance before, during pregnancy, during delivery, and the postpartum period, as well as effective management of premature newborns in the first week of life, should improve the neonatal prognosis by reducing the intra-hospital incidence of neonatal mortality in our setting.

scholarly journals FDG-PET/CT in high-risk primary breast cancer—a prospective study of stage migration and clinical impact

2020 ◽  
Author(s):  
Marianne Vogsen ◽  
Jeanette Dupont Jensen ◽  
Ivar Yannick Christensen ◽  
Oke Gerke ◽  
Anne Marie Bak Jylling ◽  
...  
Keyword(s):  
Breast Cancer ◽  
High Risk ◽  
Prospective Study ◽  
Fdg Pet ◽  
Primary Breast Cancer ◽  
Clinical Impact ◽  
Stage Migration ◽  
Pet Ct ◽  
A Prospective Study ◽  
Fdg Pet Ct

White matter microstructure in ultra-high risk and first episode schizophrenia: A prospective study

2016 ◽  
Vol 247 ◽  
pp. 42-48 ◽  
Author(s):  
Silvia Rigucci ◽  
Giulia Santi ◽  
Valentina Corigliano ◽  
Annamaria Imola ◽  
Camilla Rossi-Espagnet ◽  
...  
Keyword(s):  
White Matter ◽  
High Risk ◽  
Prospective Study ◽  
First Episode ◽  
White Matter Microstructure ◽  
Ultra High Risk ◽  
A Prospective Study ◽  
First Episode Schizophrenia

PO-09 Very high-risk patients: a prospective study of thromboembolic events in patients under thromboprophylaxis

2021 ◽  
Vol 200 ◽  
pp. S22
Author(s):  
J. Liz Pimenta ◽  
K. Ladeira ◽  
A. Teira ◽  
M. Rocha ◽  
P. Gago ◽  
...  
Keyword(s):  
High Risk ◽  
Prospective Study ◽  
Thromboembolic Events ◽  
High Risk Patients ◽  
Risk Patients ◽  
A Prospective Study ◽  
Very High

CMV Prophylaxis in High-Risk Renal Transplant Patients (D+/R-) by Acγclovir with or without Hyperimmune (CMV) Immunoglobulins: A Prospective Study

1997 ◽  
Vol 17 (6) ◽  
pp. 489-494 ◽  
Author(s):  
Lionel Rostaing ◽  
Olivier Martinet ◽  
Jean-Marc Cisterne ◽  
Josette Icart ◽  
Marie-Hélène Chabannier ◽  
...  
Keyword(s):  
High Risk ◽  
Renal Transplant ◽  
Prospective Study ◽  
Transplant Patients ◽  
Renal Transplant Patients ◽  
A Prospective Study ◽  
Cmv Prophylaxis

Letter To The Editor

PEDIATRICS ◽  
1996 ◽  
Vol 98 (1) ◽  
pp. 166-167
Author(s):  
Gabriel J. Escobar
Keyword(s):  
Lumbar Puncture ◽  
Neonatal Meningitis ◽  
Letter To The Editor ◽  
History Of

Dr Wiswell does well to remind us that selective criteria for lumbar puncture sometimes fail to identify cases of neonatal meningitis (Pediatrics 1995;95:803-806). It should not surprise us when a guideline fails. However, it does not follow that, because of this observation, one should subject every newborn suspected of sepsis (130 000 to 400 000 each year in the United States1-3) to a spinal tap. The history of neonatology is full of unfortunate events resulting from similar blanket recommendations.4

Role of Colour Doppler in High Risk Pregnancy

2021 ◽  
Vol 6 (2) ◽  
pp. 185-191
Author(s):  
Hiral Parekh ◽  
Sneha Chaudhari
Keyword(s):  
Risk Factors ◽  
High Risk ◽  
Perinatal Outcome ◽  
Umbilical Artery ◽  
High Risk Pregnancy ◽  
Colour Doppler ◽  
High Risk Factors ◽  
Risk Pregnancy ◽  
A Prospective Study

This was a prospective study conducted in pregnant patients with high risk factors who got admitted in the Department of Obstetrics and Gynaecology at Care Hospital, Jamnagar during the period from May 2018 to September 2020. Background: High-risk pregnancies causes many adverse perinatal outcomes. Doppler ultrasound is a non-invasive technique to study the feto-maternal circulation to guide the clinical management. Objective: This study aims at evaluating the role of colour Doppler in high-risk pregnancies and their perinatal outcome. Materials and Methods: This was a prospective study carried out for 29 months in the Department of Radiology with antenatal women in the age group of 18-35 years with singleton pregnancy of gestational age of <28 weeks to >35 weeks having high-risk factors considered in study. The risk factors considered were pregnancy induced hypertension (PIH), gestational diabetes, anemia, oligohydramnios, polyhydramnios and IUGR. Doppler study of umbilical artery and fetal middle cerebral artery (MCA) arteries was done and amniotic fluid index (AFI) was measured. Parameters in the form of resistive index, pulsatility index, and systolic/diastolic ratio were taken. obstetric history was taken with regular interval follow up. Results: The study was carried out with 50 patients. High-risk pregnancy was more common in the age group of 21-25 years. The most common high-risk factor in pregnancy was oligohydramnios which accounted for 30% of cases. Out of 50 high-risk pregnancies, 5 (10 %) of cases resulted in intrauterine growth restriction (IUGR). Out of 50 high-risk cases, in 36 cases, umbilical artery findings were abnormal. 3 patients had intrauterine death (IUD) and 27 patients had poor perinatal outcome. Umbilical artery abnormality showed significant sensitivity and negative predictive value for adverse (poor + IUD) perinatal. Correlation was seen between high risk pregnancy and need of emergency caesarean section and induction and associated adverse perinatal outcome. Conclusion: Combination of different arterial waveform study enhance the diagnostic accuracy in identifying those intrauterine growth restricted foetuses that were at risk. Keywords: Colour Doppler, high risk pregnancy, perinatal outcome.

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