During the existence of the Bukhara khanate, the economic and trade relations with neighboring countries on the territory of Central Asia have been largely based on transport system of the old network of roads. Along with the formation and development of communication routes, transportation vehicles also improved based on the natural climate and geographical location of different regions. In the following article the info is given on the means of the transport used in the caravan routes in the trade-economic relations of khanate of Bukhara with neighboring countries in medieval times. Included there, the starting of domestication and usage of horse drawn vehicles, camels, donkeys and others, the capacity of daily load of camels, horses, donkeys which were core of caravans, their daily distance, the necessary tasks in the incidents occurred in caravan routes (injuries, bruises, contagious diseases) the stopping regulation of caravans (sand storm, in heat and frost) is thoroughly analyzed.
