scholarly journals Temperature Changes During Cryoeffect Potentiated With Distilled Water Cryoeffect Assessed in Porcine Liver Model Without Splanchnic Blood Flow

2017 ◽  
Vol 27 (4) ◽  
pp. 348-355 ◽  
Author(s):  
Oleksiy I. Dronov ◽  
◽  
Dmytro I. Khomenko ◽  
Petro P. Bakunets ◽  
Viktoria V. Teteryna ◽  
...  
Keyword(s):  
Blood Flow ◽  
Splanchnic Blood Flow ◽  
Distilled Water ◽  
Porcine Liver ◽  
Temperature Changes ◽  
Liver Model

Liver Blood Flow as a Major Determinant of the Clearance of Recombinant Human Tissue-Type Plasminogen Activator

1992 ◽  
Vol 67 (01) ◽  
pp. 083-087 ◽  
Author(s):  
A de Boer ◽  
C Kluft ◽  
J M Kroon ◽  
F J Kasper ◽  
H C Schoemaker ◽  
...  
Keyword(s):  
Blood Flow ◽  
Rat Liver ◽  
Healthy Subjects ◽  
Liver Blood Flow ◽  
Major Determinant ◽  
Tissue Type ◽  
Perfused Rat Liver ◽  
Liver Model ◽  
Type Plasminogen Activator ◽  
Proportional Change

SummaryThe influence of changes in liver blood flow on the clearance of rt-PA was studied both in healthy subjects and in a perfused rat liver model. Liver blood flow in healthy subjects was documented indirectly by the clearance of indocyanine green (ICG). Exercise reduced liver blood flow on average by 57% with a 95% confidence interval (95% Cl) ranging from 51% to 62% (n = 5) and increased plasma levels of rt-PA activity (after an i. v. infusion of 18 mg of rt-PA over 120 min) by 119% (95% Cl, 58% - 203%) and rt-PA antigen by 91% (95% Cl, 30% - 140%). In the perfused rat liver model it was shown that halving or doubling of the physiological flow rate of a perfusate, containing rt-PA caused a proportional change in the clearance of rt-PA, while the extraction of rt-PA by the liver remained similar. In conclusion, liver blood flow is a major determinant of the clearance of rt-PA. This may have important implications for dosage of rt-PA in patients with myocardial infarction.

The effect of isradipine in acute altitude hypoxia on cerebral, renal, and splanchnic blood flow evaluated by Doppler measurements

2011 ◽  
Vol 4 (04) ◽  
pp. 212-217 ◽  
Author(s):  
Michel Court-Payen ◽  
Aram Ter Minassian ◽  
Niels Olsen ◽  
Inge Kanstrup ◽  
Claude Dubray ◽  
...  
Keyword(s):  
Blood Flow ◽  
Splanchnic Blood Flow ◽  
Altitude Hypoxia

scholarly journals Robotically Assisted Sonic Therapy as a Noninvasive Nonthermal Ablation Modality: Proof of Concept in a Porcine Liver Model

Radiology ◽  
2018 ◽  
Vol 287 (2) ◽  
pp. 485-493 ◽  
Author(s):  
Amanda R. Smolock ◽  
Mircea M. Cristescu ◽  
Eli Vlaisavljevich ◽  
Annette Gendron-Fitzpatrick ◽  
Chelsey Green ◽  
...  
Keyword(s):  
Proof Of Concept ◽  
Porcine Liver ◽  
Liver Model

SPLANCHNIC BLOOD FLOW AND OXYGEN DELIVERY ARE DECREASED IN ALCOHOL (EtOH) AND BURN INJURY.

Shock ◽  
2004 ◽  
Vol 21 ◽  
pp. 3-4
Author(s):  
M. A. Choudhry ◽  
Z. F. Ba ◽  
S. Rana ◽  
I. H. Chaudry
Keyword(s):  
Blood Flow ◽  
Oxygen Delivery ◽  
Burn Injury ◽  
Splanchnic Blood Flow

TEMPERATURE REGULATION IN EXERCISE

PEDIATRICS ◽  
1963 ◽  
Vol 32 (4) ◽  
pp. 691-702
Author(s):  
Sid Robinson
Keyword(s):  
Blood Flow ◽  
Body Temperature ◽  
Heat Stroke ◽  
The Body ◽  
Physiological Regulation ◽  
Temperature Changes ◽  
Metabolic Heat ◽  
Warm Blood ◽  
Hot Environments ◽  
Large Increments

The central body temperature of a man rises gradually during the first half hour of a period of work to a higher level and this level is precisely maintained until the work is stopped; body temperature then slowly declines to the usual resting level. During prolonged work the temperature regulatory center in the hypothalamus appears to be reset at a level which is proportional to the intensity of the work and this setting is independent of environmental temperature changes ranging from cold to moderately warm. In hot environments the resistance to heat loss may be so great that all of the increased metabolic heat of work cannot be dissipated and the man's central temperature will rise above the thermostatic setting. If this condition of imbalance is continued long enough heat stroke will ensue. We have found that in a 3 mile race lasting only 14 minutes on a hot summer day a runner's rectal temperature may rise to 41.1°C., with heat stroke imminent. The physiological regulation of body temperature of men in warm environments and during the increased metabolic heat production of work is dependent on sweating to provide evaporative cooling of the skin, and on adjustments of cutaneous blood flow which determine the conductance of heat from the deeper tissues to the skin. The mechanisms of regulating these responses during work are complex and not entirely understood. Recent experiments carried out in this laboratory indicate that during work, sweating may be regulated by reflexes originating from thermal receptors in the veins draining warm blood from the muscles, summated with reflexes from the cutaneous thermal receptors, both acting through the hypothalamic center, the activity of which is increased in proportion to its own temperature. At the beginning of work the demand for blood flow to the muscles results in reflex vasoconstriction in the skin. As the body temperature rises the thermal demand predominates and the cutaneous vessels dilate, increasing heat conductance to the skin. Large increments in cardiac output and compensatory vasoconstriction in the abdominal viscera make these vascular adjustments in work possible without circulatory embarrassment.

Splanchnic blood flow, O2 consumption, removal of lactate, and output of glucose in highlanders

1977 ◽  
Vol 43 (2) ◽  
pp. 204-210 ◽  
Author(s):  
A. Capderou ◽  
J. Polianski ◽  
J. Mensch-Dechene ◽  
L. Drouet ◽  
G. Antezana ◽  
...  
Keyword(s):  
Blood Flow ◽  
Oxygen Consumption ◽  
Splanchnic Blood Flow ◽  
O2 Consumption ◽  
Arterial Lactate ◽  
Oxygen Breathing ◽  
Arterial Blood ◽  
Splanchnic Hemodynamics ◽  
Arterial Blood Glucose ◽  
Arteriovenous Difference

An impairment of gluconeogenesis has been proposed to explain the low arterial blood glucose of highlanders. Therefore, we studied splanchnic blood flow, splanchnic uptake of oxygen and lactate, and output of glucose in nine normal and six anemic highlanders at an altitude of 3,750 m. Splanchnic blood flow, arteriovenous difference for oxygen, and oxygen consumption were comparable at rest in both groups and in lowlanders from the literature, whereas splanchnic output of glucose, and uptake of lactate were approximately twice those in lowlanders. After 10 min of mild exercise in 12 subjects (7 normals, 5 anemic), no significant changes in splanchnic hemodynamics and metabolism were found. During 29% oxygen breathing in 8 subjects (5 normals, 3 anemics), arterial lactate, splanchnic uptake of lactate and output of glucose fell to normal sea-level values. We concluded that splanchnic hemodynamics are similar in adapted highlanders and in lowlanders, and that there is no evidence of an impaired gluconeogenesis at the altitude of the present study.

Measurement of pelvic blood flow changes in response to posture in normal subjects and in women with pelvic pain owing to congestion by using a thermal technique

1992 ◽  
Vol 83 (1) ◽  
pp. 55-58 ◽  
Author(s):  
D. C. Thomas ◽  
R. W. Stones ◽  
C. M. Farquhar ◽  
R. W. Beard
Keyword(s):  
Blood Flow ◽  
Pelvic Pain ◽  
Normal Subjects ◽  
Rate Of Change ◽  
Venous Congestion ◽  
Axillary Temperature ◽  
Temperature Changes ◽  
Thermal Technique ◽  
Vaginal Temperature ◽  
Pelvic Blood Flow

1. A method is described for studying pelvic blood flow in women by the indirect method of measuring vaginal temperature changes in response to a posture change. Ten women with chronic pelvic pain and venous congestion and 10 normal subjects were observed during posture changes over a 2 h period. 2. Vaginal temperature minus axillary temperature rose after subjects changed from the supine to the seated position, indicating a fall in the rate of pelvic blood flow. 3. A significantly greater variance in the rate of change in vaginal temperature minus axillary temperature was found in patients with pelvic venous congestion compared with control subjects (P> 0.005). 4. The findings are consistent with a disorder of blood flow regulation in women with pelvic pain owing to congestion.

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