Red Book (2012)

2012 ◽  
Author(s):  
AAP Committee on Infectious Diseases
Keyword(s):  
Infectious Disease ◽  
Infectious Diseases ◽  
Medical Center ◽  
Passive Immunization ◽  
Pediatric Infectious Disease ◽  
High Yield ◽  
Evidence Based ◽  
Health Providers ◽  
Digital Version ◽  
Pediatric Infections

Full text of Doody’s Red Book 5 Star review: Description The Red Book, updated every three years by the Committee on Infectious Diseases (COID) of the American Academy of Pediatrics (AAP), is a concise summary of over 200 pediatric infectious diseases and current AAP recommendations regarding prevention, diagnosis, and management. It provides evidence-based guidance to practicing clinicians on pediatric infections and vaccinations based on the recommendations of the committee as well as the combined expertise of hundreds of physician contributors. Purpose The Red Book is larger and more comprehensive than a handbook, but is indispensible for the rapid location of information about pediatric infectious diseases and vaccines. As a single reference, it is unmatched in the field in terms of practical applicability and usefulness. This edition offers substantial revisions and additions. Audience This publication is essential for pediatric infectious diseases specialists and general pediatricians, and is useful for family medicine and emergency medicine physicians as well. Public health and school health providers, medical residents and students also will find it a high-yield source of pediatric infectious disease and vaccine information. Features Available in print and a digital version that can be downloaded onto mobile devices, this dual platform offers flexibility. The digital version contains many useful direct links to supplemental materials including recommendations and guidelines from other agencies, and an extensive collection of images depicting disease features. The book is divided into sections that cover active and passive immunization, disease summaries, antimicrobial therapy for treatment and prophylaxis, and care of children in special situations. Assessment This is an essential reference for practicing pediatricians and pediatric infectious disease specialists. The AAP COID has done an exceptional job of keeping it timely and updated, evidence-based, and comprehensive, while also rendering it accessible and engaging in format and style. The Red Book is unparalleled in content and authority on pediatric infections and their prevention and management. Reviewer: Kari A. Simonsen, MD (University of Nebraska Medical Center) Doody’s Book Review

Red Book (2015)

2015 ◽  
Keyword(s):  
Infectious Diseases ◽  
Antimicrobial Prophylaxis ◽  
Medical Center ◽  
Passive Immunization ◽  
High Yield ◽  
Injection Pain ◽  
Parasitic Infections ◽  
Health Providers ◽  
Pneumococcal Infections ◽  
Pediculosis Capitis

4-Star Review "This is an unparalleled resource in both content and authority for pediatric infectious diseases knowledge, from diagnosis to management and prevention." Kari A. Simonsen, MD, University of Nebraska Medical Center Doody's Book Review The AAP's authoritative guide to the manifestations, etiology, epidemiology, diagnosis, and treatment of more than 200 childhood conditions. The Red Book provides evidence-based guidance to practicing clinicians on pediatric infections and vaccinations based on the recommendations of the committee as well as the combined expertise of the CDC, the FDA and hundreds of physician contributors. The Red Book is an essential reference for pediatric infectious diseases specialists and general pediatricians, and is useful for family medicine and emergency medicine physicians as well. Public health and school health providers, medical residents and students also will find it a high-yield source of pediatric infectious disease and vaccine information. The book is divided into sections that cover * Active and passive immunization * Disease summaries * Antimicrobial therapy for treatment and prophylaxis * Care of children in special situations Updated information and recommendations you cannot afford to be without... * Standardized approach to disease prevention through immunizations, antimicrobial prophylaxis, and infection control practices * New chapter on Hemorrhagic Fevers Caused by Filoviruses has been added * New chapter on human parechovirus infections has been added * Updated information on hypersensitivity reactions after immunizations * The latest on sexually transmitted infections (STIs) in adolescents and children * Updated coverage of actinomycosis, amebiases, arbovirus, bacterial vaginosis, blastocystis, candidiasis, Clostridium difficle, coronaviruses, dengue, enteroviruses, Escherichia coli, Giardia intestinalis, gonococcal infections, Helicobacter pylori infections, lyme disease, meningococcal infections, pediculosis capitis, pertussis, pneumococcal infections, rotavirus, and more * Managing Injection Pain has been significantly expanded * Updated information on hepatitis C * Updated information on group B streptococcal infections * Updated section on drugs for parasitic infections * Significantly revised chapter on Respiratory Syncytial Virus * Recommendations for using MMR or MMRV vaccines have been updated * The Antimicrobial Resistance and Antimicrobial Stewardship chapter has been significantly broaded and updated * Updated information on HIV * And much more!

scholarly journals The Overton Window and a Less Dogmatic Approach to Antibiotics

2019 ◽  
Vol 70 (11) ◽  
pp. 2439-2441
Author(s):  
Daniel J Morgan
Keyword(s):  
Infectious Disease ◽  
Infectious Diseases ◽  
Trial Design ◽  
Evidence Based ◽  
Traditional Treatment ◽  
Noninferiority Trial ◽  
New Antibiotics

Abstract This analysis summarizes a set of recent, innovative trials in infectious diseases that redefine previous, non–evidence based “rules” for antibiotics. Recent trials in infectious diseases have led to reconsidering the traditional treatment of infectious diseases by changing the duration or type of traditional antibiotics or evaluating new antibiotics for approval. These trials have used the noninferiority trial approach. The noninferiority trial design and recent infectious disease trials of relevance are discussed in this viewpoint. My objective was to analyze recent trials in infectious disease and consider needs for future trials.

Red Book (2021)

2021 ◽  
Keyword(s):  
Infectious Diseases ◽  
Evidence Based ◽  
Pediatric Infections

The 32nd edition provides evidence-based guidance on pediatric infections and vaccinations based on the recommendations of the committee as well as the combined expertise of the CDC, the FDA and hundreds of contributors. https://shop.aap.org/red-book-2021-report-of-the-committee-on-infectious-diseases-32nd-edition-paperback/

scholarly journals Developing a Career in Pediatric Infectious Diseases

2018 ◽  
Vol 7 (suppl_2) ◽  
pp. S57-S59
Author(s):  
Jessica Snowden ◽  
Scott H James
Keyword(s):  
Infectious Disease ◽  
Career Development ◽  
Infectious Diseases ◽  
Pediatric Infectious Disease ◽  
Grant Writing ◽  
Annual Conference ◽  
Research Conference ◽  
Protected Time ◽  
The Many ◽  
Career Options

Abstract This article presents an overview of the Career Development session at the 17th Annual St. Jude/PIDS Pediatric Infectious Diseases Research Conference. This annual conference discusses key academic skills, such as grant writing and negotiating for protected time for research and academic endeavors, as well as highlighting the many career options available in infectious disease. This year’s session included discussions about basic science, public health, health outcomes research, and private practice pediatric infectious disease careers. The combination of practical career advice, mentoring, and inspiration offered in the career-development track talks at the St. Jude/PIDS Pediatric Infectious Diseases Research Conference this and every year helps trainees to faculty navigate the path to building a satisfying career in pediatric infectious disease.

scholarly journals Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients With Coronavirus Disease 2019 (COVID-19)

2020 ◽  
Author(s):  
Adarsh Bhimraj ◽  
Rebecca L Morgan ◽  
Amy Hirsch Shumaker ◽  
Valery Lavergne ◽  
Lindsey Baden ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Infectious Diseases ◽  
Healthcare Professionals ◽  
Critical Evaluation ◽  
Evidence Based ◽  
Efficacy And Safety ◽  
Assessment Development ◽  
Guideline Panel ◽  
Grade Approach ◽  
Pharmacologic Therapies

Abstract Background There are many pharmacologic therapies that are being used or considered for treatment of coronavirus disease 2019 (COVID-19). There is a need for frequently updated practice guidelines on their use, based on critical evaluation of rapidly emerging literature. The objective was to develop evidence-based rapid guidelines intended to support patients, clinicians, and other healthcare professionals in their decisions about treatment and management of patients with COVID-19. Methods The Infectious Diseases Society of America (IDSA) formed a multidisciplinary guideline panel of infectious disease clinicians, pharmacists, and methodologists with varied areas of expertise. Process followed a rapid recommendation checklist. The panel prioritized questions and outcomes. Then a systematic review of the peer-reviewed and gray literature was conducted. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to assess the certainty of evidence and make recommendations. Results The IDSA guideline panel agreed on 7 treatment recommendations and provided narrative summaries of other treatments undergoing evaluations. Conclusions The panel expressed the overarching goal that patients be recruited into ongoing trials, which would provide much-needed evidence on the efficacy and safety of various therapies for COVID-19, given that we could not make a determination whether the benefits outweigh harms for most treatments.

scholarly journals 1333. Developing an Educational Tool to Improve Housestaff Knowledge, Attitudes, and Behavior in Managing Common Infectious Diseases

2018 ◽  
Vol 5 (suppl_1) ◽  
pp. S407-S407
Author(s):  
Paul Jacob ◽  
Anna Person ◽  
Karen Bloch ◽  
Christina T Fiske ◽  
Kevin Kuriakose ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Soft Tissue ◽  
Infectious Diseases ◽  
Self Efficacy ◽  
Medical Center ◽  
Academic Medical Center ◽  
Soft Tissue Infections ◽  
Survey Tool ◽  
And Behavior ◽  
Antimicrobial Prescription

Abstract Background Improving internal medicine (IM) trainees skills in managing common infectious diseases is essential to their development as competent physicians. We currently lack quantitative data of the knowledge and attitudes of IM housestaff regarding their management of common infectious diseases. We applied the knowledge, attitude, and behavior model to a pre-intervention survey aimed to uncover housestaff knowledge gaps and discomfort in managing several of the most commonly encountered infectious diseases at our institution. Using this information, we plan to develop a targeted post-survey intervention to increase self-efficacy and improve antimicrobial prescription practices among trainees. Methods Survey questions were based on Infectious Disease Society of America (IDSA) guidelines and developed using an iterative process involving interviews of infectious disease physicians and IM housestaff. We chose to focus on cystitis, pneumonia, and skin and soft-tissue infections. The anonymous survey tool was developed using a secure, online platform, and distributed in January 2018. Participation was voluntary and no remuneration for participation was offered. Results Out of 165 survey recipients, 50 trainees (30%) responded. Fifty-eight percent of trainees stated that they possessed only an average level of knowledge regarding the management of cystitis, pneumonia, and cellulitis. While 98% of housestaff confirmed that they utilized additional resources for information, only 24% felt routinely comfortable making decisions without an infectious disease consultation. Ninety-six percent of trainees felt that an institution-specific guide describing the management of common infectious diseases would be highly beneficial. Conclusion Trainees still lack the knowledge and confidence to make decisions regarding the empiric management of cystitis, pneumonia, and skin and soft-tissue infections at our academic medical center. There is a strong desire for an institution-specific educational resource to provide guidance for these decisions. Increasing trainee self-efficacy and improving their antimicrobial prescription practice patterns should be an educational priority. Disclosures All authors: No reported disclosures.

scholarly journals HLA and Infectious Diseases

2009 ◽  
Vol 22 (2) ◽  
pp. 370-385 ◽  
Author(s):  
Jenefer M. Blackwell ◽  
Sarra E. Jamieson ◽  
David Burgner
Keyword(s):  
Infectious Disease ◽  
Infectious Diseases ◽  
Human Leukocyte Antigen ◽  
Molecular Basis ◽  
Selective Pressure ◽  
Human Leukocyte ◽  
Acquired Immunity ◽  
Leukocyte Antigen ◽  
Extreme Variability ◽  
Classical Human Leukocyte Antigen

SUMMARY Following their discovery in the early 1970s, classical human leukocyte antigen (HLA) loci have been the prototypical candidates for genetic susceptibility to infectious disease. Indeed, the original hypothesis for the extreme variability observed at HLA loci (H-2 in mice) was the major selective pressure from infectious diseases. Now that both the human genome and the molecular basis of innate and acquired immunity are understood in greater detail, do the classical HLA loci still stand out as major genes that determine susceptibility to infectious disease? This review looks afresh at the evidence supporting a role for classical HLA loci in susceptibility to infectious disease, examines the limitations of data reported to date, and discusses current advances in methodology and technology that will potentially lead to greater understanding of their role in infectious diseases in the future.

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