Use of Ezpap Positive Airway Pressure System for Ventilator Weaning in Pediatric Respiratory Failure

Author(s):  
Michael Mendez ◽  
Kristen Nelson McMillan
2020 ◽  
Vol 7 (1) ◽  
pp. e000711 ◽  
Author(s):  
Stuart Winearls ◽  
Ema L Swingwood ◽  
Charlotte L Hardaker ◽  
Amy M Smith ◽  
Fraser M Easton ◽  
...  

The global pandemic of COVID-19 has challenged the management of hypoxaemic respiratory failure and strained intensive care unit resources. While prone positioning (PP) is an established therapy in mechanically ventilated patients with acute respiratory distress syndrome (ARDS), its role in conscious patients is less well defined. We retrospectively reviewed our experience of implementing early PP in a cohort of 24 patients with acute hypoxaemic respiratory failure due to COVID-19 who required support with continuous positive airway pressure (CPAP). The use of PP alongside CPAP significantly increased both the ROX index and arterial oxygen pressure:fractional inspired oxygen (PaO2:FiO2) ratio from baseline values (ROX index: 7.0±2.5 baseline vs 11.4±3.7 CPAP+PP, p<0.0001; PaO2:FiO2 ratio: 143±73 mm Hg baseline vs 252±87 mm Hg CPAP+PP, p<0.01), and the changes to both the ROX index and PaO2:FiO2 ratio remained significant 1 hour after cessation of proning. The mean duration of PP in the first 24 hours was 8±5 hours. Few complications were observed and PP was continued for a mean of 10±5 days. From our experience in a dedicated COVID-19 respiratory high care unit, PP alongside CPAP therapy was feasible, tolerated, safe and improved oxygenation. The use of conscious PP in ARDS warrants further investigation in randomised controlled trials.


2012 ◽  
Vol 101 (7) ◽  
pp. e265-e266 ◽  
Author(s):  
M. Di Nardo ◽  
D. Perrotta ◽  
F. Gesualdo ◽  
G. Chidini ◽  
E. Calderini ◽  
...  

Lung India ◽  
2017 ◽  
Vol 34 (2) ◽  
pp. 216
Author(s):  
MiguelAngel Palomero Rodriguez ◽  
HéctorChozas de Arteaga ◽  
YolandaLaporta Báez ◽  
Jesúsde Vicente Sánchez ◽  
AntonioPérez Ferrer

Author(s):  
Jan Hau Lee ◽  
Ira M. Cheifetz

This chapter on respiratory failure and mechanical ventilation provides essential information about how to support children with severe respiratory disorders. The authors discuss multiple modes of respiratory support, including high-flow nasal cannula oxygen, noninvasive ventilation with continuous positive airway pressure and bilevel positive airway pressure, as well as conventional, high-frequency, and alternative modes of invasive ventilation. The section on invasive mechanical ventilation includes key information regarding gas exchange goals, modes of ventilation, patient–ventilator interactions, ventilator parameters (including tidal volume, end-expiratory pressure, and peak plateau pressure), extubation readiness testing, and troubleshooting. The authors also provide the new consensus definition of pediatric acute respiratory distress syndrome. Also included are multiple figures and indispensable information on adjunctive therapies (inhaled nitric oxide, surfactant, prone positioning, and corticosteroids) and respiratory monitoring (including capnography and airway graphics analysis).


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