Bone Structure and Metabolism

PEDIATRICS ◽  
1957 ◽  
Vol 20 (6) ◽  
pp. 1120-1120
Author(s):  
I. V. PONSETI
Keyword(s):  
Ion Exchange ◽  
Bone Tissue ◽  
Bone Structure ◽  
Body Fluids ◽  
Ciba Foundation Symposium ◽  
Exchange Column ◽  
Ion Exchange Column ◽  
Structure And Metabolism

Under the auspices of the Ciba Foundation 28 leading scientists met in London in July, 1955, to present papers and discuss current problems dealing with the structure and metabolism of bone. The proceedings of these meetings are compiled in a "Ciba Foundation Symposium." There were many important presentations. Arne Engstrom applied his methods of quantitative roentgen microscopy to osseous tissues. The slowly mineralized structures in bone tissue are in a state of very rapid cxchange with body fluids and act as an effective ion-exchange column.

A Bench-Top, Automated, High-Resolution Analyzer for Ultraviolet Absorbing Constituents of Body Fluids

1970 ◽  
Vol 16 (8) ◽  
pp. 657-661 ◽  
Author(s):  
W Wilson Pitt ◽  
Charles D Scott ◽  
Wayne F Johnson ◽  
Guy Jones
Keyword(s):  
High Resolution ◽  
Ion Exchange ◽  
Exchange Resin ◽  
Ion Exchange Resin ◽  
Body Fluids ◽  
Prototype System ◽  
Exchange Column ◽  
Laboratory Bench ◽  
Dual Beam ◽  
Ion Exchange Column

Abstract An automated, high-resolution chromatograph capable of separating as many as 150 ultraviolet-absorbing molecular constituents of body fluids has been previously developed. A smaller, improved version of this analyzer, which uses only one-eighth of the previously required quantity of ion-exchange resin, sample, and eluant, is described. Analysis time has been decreased from 40 to 20 h. A prototype system of this analyzer, which will fit on an ordinary laboratory bench top, has been built and is now being tested. The small prototype analyzer uses a folded, 0.22-cm ion-exchange column for separation and a recently developed dual-beam, dual-wavelength, uv-flow photometer for detection. A unique device has been developed to generate the buffer concentration gradient used in eluting the ion-exchange column. Analyses of body fluids with this prototype are comparable to those achieved with the larger analyzers.

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