INTRACARDIAC PHONOCARDIOGRAPHY IN THE DIAGNOSIS OF CONGENITAL HEART DISEASE

Intracardiac phonocardiography, the recording of sounds from within the heart, has been carried out with 63 patients with congenital heart disease. Studies have also been done with 11 patients in the pediatric age range who did not have heart disease. This new technique of recording heart sounds has been shown to provide a degree of localization of heart sounds and murmurs not heretofore obtainable. It is by virtue of this property that intracardiac phonocardiography has an important place in the diagnosis of congenital heart disease. Records from several lesions are shown to illustrate this point. It is believed that intracardiac phonocardiography should be made a part of the routine studies done at the time of cardiac catheterization. The prospects for intracardiac phonocardiography are discussed.

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Cardiac Catheterization in Congenital Heart Disease

PEDIATRICS ◽

10.1542/peds.4.3.389a ◽

1949 ◽

Vol 4 (3) ◽

pp. 389-389

Keyword(s):

Blood Pressure ◽

Congenital Heart Disease ◽

Blood Flow ◽

Heart Disease ◽

Cardiac Catheterization ◽

Pulmonary Blood Flow ◽

Congenital Heart ◽

Diagnostic Approach ◽

Important Place

Among the newer methods of diagnosis in congenital malformatons of the heart, cardiac catheterization holds an important place. The authors set forth the essentials of this diagnostic approach. The monograph is divided into 2 parts. The 1st part deals with the equipment, technics and procedures involved, the roentgenographic observations, the patterns of the blood pressure tracings and the methods of computation of systemic and pulmonary blood flow. The importance of a well trained team to carry out these studies with accuracy and safety is emphasized.

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Thrombin generation in paediatric patients with congenital heart disease

Hämostaseologie ◽

10.1055/s-0037-1617119 ◽

2008 ◽

Vol 28 (S 01) ◽

pp. S61-S66 ◽

Cited By ~ 1

Author(s):

G. Cvirn ◽

A. Rosenkranz ◽

B. Leschnik ◽

W. Raith ◽

W. Muntean ◽

...

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Negative Correlation ◽

Congenital Heart ◽

Thrombin Generation ◽

Significant Negative Correlation ◽

Peak Height ◽

Global Test ◽

Paediatric Patients ◽

Age Range

SummaryThrombin generation was studied in paediatric patients with congenital heart disease (CHD) undergoing cardiac surgery using the calibrated automated thrombography (CAT) in terms of the lag time until the onset of thrombin formation, time to thrombin peak maximum (TTP), endogenous thrombin potential (ETP), and thrombin peak height. The suitability to determine the coagulation status of these patients was investigated. Patients, material, methods: CAT data of 40 patients with CHD (age range from newborn to 18 years) were compared to data using standard coagulation parameters such as prothrombin (FII), antithrombin (AT), tissue factor pathway inhibitor (TFPI), prothrombin fragment 1.2 (F 1.2), thrombin-antithrombin (TAT), activated partial thromboplastin time (aPTT), and prothrombin time (PT). Results: A significant positive correlation was seen between ETP and FII (p < 0.01; r = 0.369), as well as between peak height and F II (p < 0.01; r = 0.483). A significant negative correlation was seen between ETP and TFPI values (p < 0.05; r = –0.225) while no significant correlation was seen between peak height and TFPI. A significant negative correlation was seen between F 1.2 generation and ETP (p < 0.05; r = –0.254) and between F 1.2 generation and peak height (p < 0.05; r = –0.236). No correlation was seen between AT and ETP or peak. Conclusions: CAT is a good global test reflecting procoagulatory and inhibitory factors of the haemostatic system in paediatric patients with CHD.

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Cardiac Catheterization in Congenital Heart Disease, A Clinical and Physiological Study in Infants and Children

American Journal of Clinical Pathology ◽

10.1093/ajcp/19.9.851 ◽

1949 ◽

Vol 19 (9) ◽

pp. 851-851 ◽

Cited By ~ 1

Author(s):

L. T. Iseri

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Cardiac Catheterization ◽

Congenital Heart ◽

Infants And Children ◽

Physiological Study ◽

In Infants And Children

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EMOTIONAL IMPLICATIONS OF CONGENITAL HEART DISEASE IN CHILDREN

PEDIATRICS ◽

10.1542/peds.33.3.367 ◽

1964 ◽

Vol 33 (3) ◽

pp. 367-379

Author(s):

Helen H. Glaser ◽

Grace S. Harrison ◽

David B. Lynn

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Cardiac Catheterization ◽

Congenital Heart ◽

Physician’S Role ◽

Active Life ◽

Heart Operation ◽

Physician's Role ◽

Specific Impact

Mothers of 25 children with congenital heart disease were interviewed to elicit family reactions to the patient's disorder. Problems for parents included: vague apprehension about the behavior of the newborn, uncertainty about the diagnosis, anxiety about the child's symptoms, fears of death, feelings of guilt, disappointment and irritation with their burden, overprotective attitudes, attempts to provide the child with a normal active life, difficulties with discipline, and various problems related to hospitalization, cardiac catheterization, and heart operation. The physician's role in management of such patients is aided by awareness on his part of the general and specific impact of this handicapping disorder of childhood.

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