THROMBOCYTOSIS, CENTRAL NERVOUS SYSTEM DISEASE, AND MYOCARDIAL INFARCTION PATTERN IN INFANCY

PEDIATRICS ◽  
1966 ◽  
Vol 38 (4) ◽  
pp. 629-636
Author(s):  
Shyamal K. Sanyal ◽  
Richard B. Yules ◽  
Arthur I. Eidelman ◽  
Norman S. Talner

Two infants with thrombocytosis and significant neurological symptoms are presented. The electrocardiographic and vectorcardiographic findings in both suggested apical myocardial infarction. The isoenzyme studies done in one infant, however, did not support this diagnosis. This observation raises the possibility that the electrocardiographic and vectorcardiographic abnormalities may be due to associated central nervous system disease rather than due to a compromised coronary blood flow.

2016 ◽  
Vol 65 (35) ◽  
pp. 930-933 ◽  
Author(s):  
Anita D. Sircar ◽  
Francisca Abanyie ◽  
Dean Blumberg ◽  
Peter Chin-Hong ◽  
Katrina S. Coulter ◽  
...  

2020 ◽  
Vol 60 (1) ◽  
pp. 291-309 ◽  
Author(s):  
Jesse A. Stokum ◽  
Volodymyr Gerzanich ◽  
Kevin N. Sheth ◽  
W. Taylor Kimberly ◽  
J. Marc Simard

Cerebral edema, a common and often fatal companion to most forms of acute central nervous system disease, has been recognized since the time of ancient Egypt. Unfortunately, our therapeutic armamentarium remains limited, in part due to historic limitations in our understanding of cerebral edema pathophysiology. Recent advancements have led to a number of clinical trials for novel therapeutics that could fundamentally alter the treatment of cerebral edema. In this review, we discuss these agents, their targets, and the data supporting their use, with a focus on agents that have progressed to clinical trials.


2021 ◽  
Vol 432 ◽  
pp. 213751
Author(s):  
Ke Chen ◽  
Si Sun ◽  
Junying Wang ◽  
Xiao-Dong Zhang

2019 ◽  
Vol 59 (5) ◽  
pp. E33-E37
Author(s):  
Stefano C. Previtali ◽  
Marina Scarlato ◽  
Paolo Vezzulli ◽  
Alessandra Ruggieri ◽  
Daniele Velardo ◽  
...  

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