Rheumatic Fever, ed. 2 (vol. II in the series Major Problems in Clinical Pediatrics), by Milton Markowitz, M.D., and Leon Gordis, M.D., Dr.P.H. Philadelphia/London/Toronto: W. B. Saunders, 1972, 309 pp., $11.50

PEDIATRICS ◽  
1973 ◽  
Vol 51 (6) ◽  
pp. 1117-1118
Author(s):  
Benedict F. Massell
Keyword(s):  
Heart Disease ◽  
Rheumatic Fever ◽  
Rheumatic Heart Disease ◽  
Half Century ◽  
The Past ◽  
Past Half Century ◽  
And Control ◽  
Past Half ◽  
Rheumatic Heart

Although a number of texts devoted to special aspects of rheumatic fever have appeared within the past half century, Milton Markowitz, first in the 1965 edition with Ann Kuttner and now in an updated and amplified edition with Leon Gordis, has provided the first objective and comprehensive monograph on this disease since 1924, when Carey Coombs's Rheumatic Heart Disease was published. In view of the advances in our knowledge of the etiology and control of rheumatic fever that have been made since the days of Carey Coombs, this monograph by Markowitz and Gordis answers a long felt need.

scholarly journals Rheumatic heart disease among Omani schoolchildren

1997 ◽  
Vol 3 (1) ◽  
pp. 17-23
Author(s):  
Aly A. Hasab ◽  
Ali Jaffer ◽  
Abdulla M. Riyami
Keyword(s):  
Heart Disease ◽  
Rheumatic Fever ◽  
Rheumatic Heart Disease ◽  
School Health ◽  
Primary Health Care System ◽  
Primary Health ◽  
Significant Difference ◽  
And Control ◽  
Rheumatic Heart

Screening of 9904 Omani schoolchildren from different regions in Oman gave a prevalence rate of rheumatic heart disease of 8 per 10 000 with no significant difference by sex or level of education. Follow-up of the sample for three months gave an estimated annual incidence of rheumatic fever of 4 per 10 000. The positive predictive value of definite murmurs for diagnosis of cardiovascular disease was 35.21% for school health physicians and 86.67% for regional physicians. The results show that rheumatic fever and rheumatic heart disease are not major public health problems in Oman. The study recommends integration of the management and control of the diseases within the primary health care system

Increased ischaemia-modified albumin is associated with inflammation in acute rheumatic fever

2013 ◽  
Vol 24 (3) ◽  
pp. 430-436 ◽  
Author(s):  
Zehra Karataş ◽  
Tamer Baysal ◽  
Fatih Şap ◽  
Hayrullah Alp ◽  
Idris Mehmetoğlu
Keyword(s):  
Heart Disease ◽  
Rheumatic Fever ◽  
Rheumatic Heart Disease ◽  
Heart Valve ◽  
Congenital Heart ◽  
Acute Rheumatic Fever ◽  
Valve Disease ◽  
Heart Valve Disease ◽  
And Control ◽  
Rheumatic Heart

AbstractIntroduction: Ischaemia-modified albumin, a novel biochemical marker for tissue ischaemia, was found to be associated with oxidative stress. The purpose of this study was to assess the role of ischaemia-modified albumin in the diagnosis of acute rheumatic fever and also to evaluate the ischaemia-modified albumin levels in children with heart valve disease. Methods: The study groups, aged 5–18 years, consisted of 128 individuals – 40 with acute rheumatic fever, 35 with congenital heart valve disease, 33 with chronic rheumatic heart disease, and 20 healthy control subjects. Results: The ischaemia-modified albumin, erythrocyte sedimentation rate, and C-reactive protein levels of the acute rheumatic fever group were significantly higher than those in the chronic rheumatic heart disease, congenital heart valve disease, and control groups, separately (p < 0.001). The ischaemia-modified albumin levels in both carditis and isolated arthritis subgroups of children with acute rheumatic fever were significantly higher than in the control group (p < 0.001, p < 0.01, respectively). However, there was no statistically significant difference between the chorea subgroup and control subjects. In addition, significant correlations were observed between ischaemia-modified albumin and acute phase reactants of patients with acute rheumatic fever (p < 0.001 for both erythrocyte sedimentation rate and C-reactive protein). The ischaemia-modified albumin levels of chronic rheumatic heart disease, congenital heart valve disease, and control subjects were similar. Conclusions: The increased level of ischaemia-modified albumin in children with acute rheumatic fever seems to be associated with inflammation. However, further studies are needed to provide stronger evidence.

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