Medical Care of Newborn Babies: Clinics in Developmental Medicine Nos. 44/45, by Pamela A, Davies, R. J. Robinson, J. W. Scopes, J. P. M. Tizard, and J. S. Wigglesworth, Spastics International Medical Publications. London: William Heinemann Medical Books, Ltd., Philadelphia: J. B. Lippincott Company, 1972, $22.50

PEDIATRICS ◽  
1974 ◽  
Vol 54 (1) ◽  
pp. 126-127
Author(s):  
Clement A. Smith

Five Senior Members of the Hammersmith Hospital (London) Neonatal Research Unit have here produced an excellent and unusual book. They say it originated as the instructions for the unit's resident staff—"revised when too heavily amended by entries in the departmental diary or when superseded by departmental folklore handed down from resident to resident." (What better winnowing of the clinical wheat from the academic chaff?) While offering details necessary for use in a maternity department with a well-staffed and equipped intensive care unit, the practical viewpoint and clear style of the five authors will render their advice immediately useful to any physician, with or without a blood gas analyzer or a thermistor, when faced with a prenatal, perinatal, or neonatal problem.

Author(s):  
Antti A.M. Luukkonen ◽  
Tiina M. Lehto ◽  
Pirjo S.M. Hedberg ◽  
Tommy E. Vaskivuo

AbstractIntensive care units, operating rooms, emergency departments, and neonatology units need rapid measurements of blood gases, electrolytes, and metabolites. These analyses can be performed in a central laboratory or at the clinic with traditional or compact cassette-type blood gas analyzers such as the epoc blood gas testing system for analyzing whole blood samples at the bedside. In this study, the performance and interchangeability of a hand-held epoc blood gas analyzer was evaluated.The analytical performance of the epoc analyzer was evaluated by determining within-and between-run precisions. The accuracy of the epoc analyzer was assessed by comparing patient results from the device with those obtained with the Siemens Rapidlab 1265 and Rapidpoint RP500 and Siemens Dimension Vista and Sysmex XE-2100 analyzers. The following parameters were measured: pH, pCOThe CV% of the epoc’s between-day imprecision for the various parameters varied from 0.4 to 8.6. The within-run imprecision CV% varied from 0.6 to 5.2. The squared regression coefficient (RWith most of the measured blood gas parameters, the epoc analyzer correlated well with reference techniques. The epoc analyzer is suitable for rapid measurement of the blood gases, the electrolytes, and the metabolites in the ICU.


Author(s):  
Helena Claerhout ◽  
Martine De Prins ◽  
Dieter Mesotten ◽  
Greet Van den Berghe ◽  
Chantal Mathieu ◽  
...  

AbstractWe verified the analytical performance of strip-based handheld glucose meters (GM) for prescription use, in a comparative split-sample protocol using blood gas samples from a surgical intensive care unit (ICU).Freestyle Precision Pro (Abbott), StatStrip Connectivity Meter (Nova), ACCU-CHEK Inform II (Roche) were evaluated for recovery/linearity, imprecision/repeatability. The GMs and the ABL90 (Radiometer) blood gas analyzer (BGA) were tested for relative accuracy vs. the comparator hexokinase glucose-6-phosphate-dehydrogenase (HK/G6PDH) assay on a Cobas c702 analyzer (Roche).Recovery of spiked glucose was linear up to 19.3 mmol/L (347 mg/dL) with a slope of 0.91–0.94 for all GMs. Repeatability estimated by pooling duplicate measurements on samples below (n=9), in (n=51) or above (n=80) the 4.2–5.9 mM (74–106 mg/dL) range were for Freestyle Precision Pro: 4.2%, 4.0%, 3.6%; StatStrip Connectivity Meter: 4.0%, 4.3%, 4.5%; and ACCU-CHEK Inform II: 1.4%, 2.5%, 3.5%. GMs were in agreement with the comparator method. The BGA outperformed the GMs, with a MARD of 3.9% compared to 6.5%, 5.8% and 4.4% for the FreeStyle, StatStrip and ACCU-CHEK, respectively. Zero % of the BGA results deviated more than the FDA 10% criterion as compared to 9.4%, 3.7% and 2.2% for the FreeStyle, StatStrip and ACCU-CHEK, respectively. For all GMs, icodextrin did not interfere. Variation in the putative influence factors hematocrit and OGMs quantified blood glucose in whole blood at about the 10% total error criterion, proposed by the FDA for prescription use.


1973 ◽  
Vol 19 (11) ◽  
pp. 1243-1247 ◽  
Author(s):  
P A Drinker ◽  
D C Noonan ◽  
N Ramanaiah ◽  
J R Tole

Abstract Two different blood-gas analyzers were tested to determine the effects on blood pH measurement of changing the reference bridge solution from saturated KCl to normal saline (0.16 mol of NaCl per liter). This change, which necessitated the preparation of modified buffers equimolal in NaCl with respect to blood, virtually eliminated salt depletion of the bridge solution and improved the stability of the liquid-junction potential between the bridge solution and the sample. The instruments we used were the Corning 165 pH Blood Gas Analyzer and the Radiometer E5021 pH Electrode with PHM72 Acid Base Analyzer. Comparison of results on clinical blood samples indicates that performance with the modified bufferbridge system is the same as that obtained with the conventional scheme. Analytical performances of the Corning and Radiometer instruments for PO2 and PCO2, as well as for pH, were comparable.


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