Islet Cell Tumor in a Neonate: Diagnosis by Selective Angiography and Histological Findings

PEDIATRICS ◽  
1978 ◽  
Vol 61 (5) ◽  
pp. 790-791
Author(s):  
John Kirkland ◽  
Yoram Ben-Menachem ◽  
Mohammad Akhtar ◽  
Robert Marshall ◽  
Stanley Dudrick

Congenital islet cell adenomas of the pancreas are rare. Fewer than 20 cases have been documented.1,2 The purpose of this article is to present what we believe is the first case in which a preoperative diagnosis of an insulinoma was established by selective angiography in a neonate and to describe the histological findings. CASE REPORT A girl weighing 2,759 gm was the product of a normal 38-week pregnancy with an uncomplicated labor and delivery. The one- and five-minute Apgar scores were 8 and 9. At 19 hours of age she was observed to be cold, pale, and diaphoretic. A sepsis evaluation was initiated.

1997 ◽  
Vol 37 (3) ◽  
pp. 479
Author(s):  
Keun Young Kong ◽  
Dong Ho Lee ◽  
Young Tae Ko ◽  
Young Wha Kim

1989 ◽  
Vol 39 (5) ◽  
pp. 328-335
Author(s):  
Akitaka Nonomura ◽  
Yuji Mizukami ◽  
Fujitsugu Matsubara ◽  
Naoko Kono ◽  
Yasuni Nakanuma

CytoJournal ◽  
2005 ◽  
Vol 2 ◽  
pp. 8 ◽  
Author(s):  
Sarah M Bean ◽  
Mohamad A Eloubeidi ◽  
Isam A Eltoum ◽  
Robert J Cerfolio ◽  
Darshana N Jhala

We report the first case of a posterior mediastinal granular cell tumor initially diagnosed on cytologic material obtained via endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) in a 51-year-old male with a prior history of colon cancer. Aspirates obtained were cellular and composed of polygonal cells with abundant granular cytoplasm and small, round dark nuclei. An immunoperoxidase stain performed on the cell block for antibodies to S-100 protein showed strong, diffuse staining of the cytoplasmic granules. Electron microscopy performed on the cell block revealed numerous cytoplasmic lysosomes. This is the first case report in the English literature of a definitive preoperative diagnosis of a mediastinal granular cell tumor utilizing material obtained via EUS-FNA.


2001 ◽  
Vol 56 (6) ◽  
pp. 183-188 ◽  
Author(s):  
Cassio C. Dal Coleto ◽  
Ana Paula F. de Mello ◽  
Jaime Piquero-Casals ◽  
Fábio R. Lima ◽  
Maria Aparecida Constantino Vilela ◽  
...  

Necrolytic migratory erythema is a rare skin condition that consists of migrating areas of erythema with blisters that heal with hyperpigmentation. It usually occurs in patients with an alpha islet cell tumor of the pancreas-or glucagonoma-and when associated with glucose intolerance, anemia, hyperglucagonemia, and weight loss defines the glucagonoma syndrome. We describe a 52-year-old female patient with necrolytic migratory erythema associated with glucagonoma syndrome who had metastatic disease at presentation and passed away one week after her admission. The autopsy showed a tumor in the body of the pancreas, which was diagnosed as a neuroendocrine tumor and confirmed by immunohistochemistry. The diagnosis of necrolytic migratory erythema is a matter of great importance, since it might be an auxiliary tool for the early detection of glucagonoma.


PEDIATRICS ◽  
1971 ◽  
Vol 47 (3) ◽  
pp. 594-598
Author(s):  
Richard M. Buchta ◽  
J. M. Kaplan

In 1955, Zollinger and Ellison1 described a syndrome consisting of peptic ulceration, marked gastric hypersecretion, and non-beta islet cell tumor of the pancreas. Although there have been over 300 cases in the adult literature2-5 only 19 patients, 16 years old or younger have been reported. We add one more child to this growing list and review the clinical data of the known cases described. Case Report The patient (R.L.) was a 9-year-old Negro male with a 7-month history of intermittent episodes of mid-epigastric abdominal pain. The pain was somewhat relieved by eating, or the use of antispasmodics. During this period of time, the child had occasional episodes of vomiting, but no melena or hematemesis.


1990 ◽  
Vol 23 (7) ◽  
pp. 1897-1901
Author(s):  
Satoshi Ambiru ◽  
Hajime Yamano ◽  
Kohji Nagano ◽  
Masanobu Kure ◽  
Hiroshi Masaoka ◽  
...  

2015 ◽  
Vol 23 (30) ◽  
pp. 4923
Author(s):  
Ying-Nan Wang ◽  
Jian Liu ◽  
Ming-Hao Wu ◽  
Yu Gao ◽  
Xiao-Yan Liu ◽  
...  

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