Transcutaneous Arterial Oxygen Tension and Retrolental Fibroplasia

PEDIATRICS ◽  
1987 ◽  
Vol 80 (5) ◽  
pp. 766-766
Author(s):  
D. WILLARD ◽  
J. MESSER

To the Editor.— According to Rooth et al1 transcutaneous monitoring of the newborn gives a reliable indication of arterial oxygen tension, if correctly used. We have evidence2 confirming such a point of view, often considered as controversial in the United States. Since 1980, we have used this system of monitoring, without any additional blood control, on every oxygen-dependent newborn treated in our neonatal care unit with few exceptions. From January 1980 to July 1986, 1,672 premature infants (approximately one third of whom weighed less than 1,500 g) were assessed by means of indirect ophthalmoscopy to rule out classical forms of retinopathy.

PEDIATRICS ◽  
1971 ◽  
Vol 47 (6) ◽  
pp. 1086-1087
Author(s):  
Jerold F. Lucey ◽  
Marvin Cornblath ◽  
Stanley N. Graven ◽  
Sheldon B. Korones ◽  
L. Stanley James ◽  
...  

The following recommendations will appear in the revision of the manual, Standards and Recommendations for Hospital Care of Newborn Infants, scheduled for publication early in 1971. Because the Committee felt a sense of urgency to provide these recommendations to pediatricians, family physicians, and other health professionals caring for newborn infants, they are being published prior to appearance of the manual. The statement has had extensive review by a large number of experts not on the Committee, and their comments and suggestions have been followed in the preparation of the final draft. It was also reviewed and approved by the Committee on Drugs of the Academy at their meeting in San Francisco October 24, 1970. When a newborn infant needs extra oxygen, it must be administered with great care because there is a causal relationship between a higher than normal oxygen tension in arterial blood (60 to 100 mm Hg) and retrolental fibroplasia (retinopathy of prematurity). When the normal O2 tension is exceeded, there is an increased risk of retrolental fibroplasia. The upper limit of arterial oxygen tension and its duration which are safe for these infants is not known. It is probable that even concentrations of 40% of inspired oxygen (formerly considered safe) could be dangerous for some infants. An inspired oxygen concentration of 40% may be insufficient for infants with cardiorespiratory disease to raise the oxygen tension of arterial blood to a normal level. In such instances, an inspired oxygen concentration of 60%, 80%, or higher may be necessary.


PEDIATRICS ◽  
1981 ◽  
Vol 67 (1) ◽  
pp. 160-161
Author(s):  
Avron Y. Sweet

In their recent article Clarke et al (Pediatrics 65:884, 1980) advocate the use of transcutaneous oxygen monitors during the transport of certain newborn infants. In support of their position, the authors state, ". . . hyperoxia is a serious cause of morbidity to the small preterm infant. Exposure to hyperoxia for a period as short as 30 minutes has, on occasion, been associated with the occurrence of retrolental fibroplasia (RLF). Hyperoxia has also been postulated as an important cause of bronchopulmonary dysplasia . . . ." Their clear message is that a brief occurrence of above usual arterial oxygen tension may result in RLF.


1987 ◽  
Vol 25 (3) ◽  
pp. 199-208 ◽  
Author(s):  
STEVEN J. BARKER ◽  
KEVIN K. TREMPER

1996 ◽  
Vol 23 (2) ◽  
pp. 75-77
Author(s):  
P. Dobromylskyj ◽  
P.M. Taylor ◽  
J.C. Brearley ◽  
C.B. Johnson ◽  
S.P.L. Luna

PEDIATRICS ◽  
1972 ◽  
Vol 50 (2) ◽  
pp. 219-228
Author(s):  
Henrique Rigatto ◽  
June P. Brady

We studied nine healthy preterm infants during the first 35 days of life to define the relationship between periodic breathing, apnea, and hypoxia. For this purpose we compared ventilation/apnea (V/A), minute ventilation, and alveolar and capillary blood gases during periodic breathing induced by hypoxia and during spontancous periodic breathing in room air. We induced periodic breathing by giving the baby in sequence 21, 19, 17, and 15% O2 to breathe for 5 minutes each, and also by giving 21, 15, and 21% O2. We measured ventilation with a nosepiece and a screen flowmeter. With a decrease in arterial oxygen tension, preterm infants (1) hypoventilated, (2) breathed periodically more frequently, and (3) showed a decrease in V/A due to an increase in the apneic interval. In one baby this led to apnea lasting 30 seconds. These findings support our hypothesis that preterm infants breathing periodically hypoventilate and suggest that hypoxia may be a primary event leading to periodic breathing and apnea.


1974 ◽  
Vol 85 (2) ◽  
pp. 254-261 ◽  
Author(s):  
Arnold W. Strauss ◽  
Marilyn Escobedo ◽  
David Goldring

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