Radionuclide Imaging for Assessment of Patients with Atrial Fibrillation

2009 ◽  
Vol 5 (1) ◽  
pp. 20
Author(s):  
Todd D Miller ◽  
J Wells Askew ◽  
◽  
Keyword(s):  
Atrial Fibrillation ◽  
Heart Disease ◽  
Single Photon ◽  
Photon Emission ◽  
Left Ventricular ◽  
Emission Computed Tomography ◽  
Pericardial Disease ◽  
Spect Mpi ◽  
Spect Myocardial Perfusion ◽  
Artery Disease

Atrial fibrillation is a common arrhythmia affecting more than 2 million adults in the US. There is a well-recognized association between atrial fibrillation and cardiovascular disease. Associated cardiovascular conditions include coronary artery disease (CAD), hypertension, left ventricular dysfunction (systolic and/or diastolic), valvular heart disease, pericardial disease, congenital heart disease and pulmonary embolus. Single-photon-emission computed tomography (SPECT) myocardial perfusion imaging (MPI) can be useful for assessment of underlying CAD in patients with atrial fibrillation. The decision to employ SPECT MPI in an individual patient with atrial fibrillation should depend on the clinical characteristics of the patient that generally would warrant the use of a SPECT study and not solely on the presence of atrial fibrillation.

P606High intermodality variability in ejection fraction measured by echocardiography, cardiac magnetic resonance and single photon emission computed tomography in chronic coronary artery disease patients

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
T M Stokke ◽  
S I Sarvari ◽  
A W Bjerring ◽  
K H Haugaa ◽  
M T Elahi ◽  
...  
Keyword(s):  
Single Photon ◽  
Photon Emission ◽  
Left Ventricular ◽  
Emission Computed Tomography ◽  
Single Photon Emission ◽  
Chronic Coronary Artery Disease ◽  
Single Photon Emission Computed ◽  
Artery Disease ◽  
Dimensional Echocardiography ◽  
Photon Emission Computed Tomography

Abstract Background Clinical treatment strategies are often based on measurement of left ventricular ejection fraction (LVEF). There is limited evidence about variations in LVEF when measured by different imaging modalities. Purpose To investigate the intermodality variability of LVEF measured by two-dimensional echocardiography (2DE), three-dimensional echocardiography (3DE), cardiac magnetic resonance (CMR), and single photon emission computed tomography (SPECT) in patients with chronic coronary artery disease (CAD). Methods Patients from a multicenter study (DOPPLER-CIP – Determining optimal noninvasive parameters for the prediction of left ventricular remodeling in chronic ischemic patients) with chronic CAD were included. LVEF was measured by CMR and at least one additional modality. In each modality, LVEF was measured by a core laboratory independently of the other modalities. Measurements of LVEF by CMR were compared to 2DE, 3DE and SPECT using correlation and Bland-Altman plots. Results A total of 343 patients were included. Mean age was 63.9±8.3 years and 253 (74%) were males. Mean LVEF by CMR was 61.8±11.6%. Correlations between CMR LVEF and other modalities were moderate for 2DE and 3DE, and good for SPECT (Figure A-C). CMR had significantly greater correlation to SPECT, compared to 2DE and 3DE. Bland-Altman plots indicated relatively wide limits of agreement between all modalities, ranging from 31% to 42% (Figure, D-F). Mean absolute difference of LVEF between CMR and other modalities were 8.5% for 2DE, 9.0% for 3DE, and 8.3% for SPECT. The percentage of measurements that fell within a range of 5% difference compared to CMR LVEF was 41% for 2DE, 34% for 3DE and 37% for SPECT (all p>0.05). Conclusions In a multicenter study with chronic CAD patients, LVEF assessed by CMR had better correlation to SPECT, compared to 2DE and 3DE. However, there was considerable variability among all three modalities that were compared to CMR. Awareness of these variations are important in clinical management.

Dilated cardiomyopathy

2021 ◽  
pp. 661-680
Author(s):  
Upasana Tayal ◽  
Sanjay Prasad ◽  
Tjeerd Germans ◽  
Albert C. van Rossum
Keyword(s):  
Dilated Cardiomyopathy ◽  
Single Photon ◽  
Management Strategies ◽  
Photon Emission ◽  
Left Ventricular ◽  
Emission Computed Tomography ◽  
Positron Emission ◽  
Single Photon Emission Computed ◽  
Artery Disease ◽  
Photon Emission Computed Tomography

Dilated cardiomyopathy (DCM) is characterized by enlargement of the heart with associated reduced left ventricular function. From an imaging perspective, important requirements are to exclude other pathologies, assess disease severity, guide therapeutic management, and identify complications. Establishing the imaging diagnosis of DCM is key to guiding the management of DCM. In this chapter we discuss how to use imaging to make an accurate diagnosis of DCM, and review how to exclude coronary artery disease (CAD) and valvular disease as these are two important differentials with differing management strategies. We then review the diagnostic and prognostic capabilities of echocardiography, cardiovascular magnetic resonance imaging (CMR) and nuclear techniques including single-photon emission computed tomography (SPECT) and positron emission tomography (PET) in DCM, with a focus on where imaging can identify particular causes of DCM.

scholarly journals Detecting Myocardial Ischemia With 99mTechnetium-Tetrofosmin Myocardial Perfusion Imaging in Ischemic Stroke

2017 ◽  
Vol 7 (4) ◽  
pp. 164-168 ◽  
Author(s):  
Sotirios Giannopoulos ◽  
Sofia Markoula ◽  
Chrissa Sioka ◽  
Sofia Zouroudi ◽  
Maria Spiliotopoulou ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Myocardial Perfusion Imaging ◽  
Myocardial Perfusion ◽  
Myocardial Ischemia ◽  
Perfusion Imaging ◽  
Single Photon ◽  
Photon Emission ◽  
Emission Computed Tomography ◽  
Spect Mpi ◽  
Artery Disease

Background: To assess the myocardial status in patients with stroke, employing myocardial perfusion imaging (MPI) with 99mTechnetium-tetrofosmin (99mTc-TF)-single-photon emission computed tomography (SPECT). Methods: Fifty-two patients with ischemic stroke were subjected to 99mTc-TF-SPECT MPI within 1 month after stroke occurrence. None of the patients had any history or symptoms of coronary artery disease or other heart disease. Myocardial perfusion imaging was evaluated visually using a 17-segment polar map. Myocardial ischemia (MIS) was defined as present when the summed stress score (SSS) was >4; MIS was defined as mild when SSS was 4 to 8, and moderate/severe with SSS ≥9. Patients with SSS >4 were compared to patients with SSS <4. Parameters such as age, body mass index, waist perimeter, smoking habits, and medical history (diabetes mellitus, dyslipidemia, etc) were evaluated according to MPI results. Results: Myocardial ischemia was present in 32 (62%) of 52 patients with stroke. Among them, 20 (62%) of 32 patients had mild abnormalities and 12 (38%) of 32 had moderate/severe. The age and waist perimeter showed a tendency to relate to severe MIS when patients with SSS >9 were compared to patients with SSS <4. In MPI-positive patients, an age was to be association with SSS, with the oldest age exhibiting the highest SSS ( P = .01). The association of age with SSS remained statistically significant in the multivariate analysis ( P = .04). Conclusion: The study suggested that more than half of patients with stroke without a history of cardiac disease have MIS. Although most of them have mild MIS, we suggest a thorough cardiological evaluation in this group of patients for future prevention of severe myocardial outcome.

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