Radon exposure and lung cancer: analysis of risk for residents of Rivne City (Ukraine)

The comparison of complex epidemiological (cohort, case-control and ecological) studies of Radon influence on incidence of lung cancer among mining populations of world mines and residents of the city of Rivne was conducted. The calculation of additional relative risk for the residents of the city of Rivne by the method of epidemiological ecological studies performed on radiometric equipment AlfaRad+and calculated according to the BEIR VI risk model in two variants: exposure-age-duration (EAD) and exposure -age-concentration (EAC) was conducted. The values of the risk coefficients of the dependencies of the relative risk on Radon exposure we obtained for residents of Rivne are lower than the ones obtained for miners (according to literature) – 0.31 (EAD) and 0.49 (EAC) per 100 WLM for volumetric activity (VA) of Radon in housing 200 Bq/m3 and 1420 Bq/m3. The thesis about the impossibility of automatically applying the obtained dependencies of additional relative risk of lung cancer on exposure to Radon for miners to the general population according to the variants of risk models proposed in BEIR VI was verified.

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A Retrospective Look at Rn-induced Lung Cancer Mortality From the Viewpoint of a Relative Risk Model

Health Physics ◽

10.1097/00004032-198806000-00004 ◽

1988 ◽

Vol 54 (6) ◽

pp. 635-643 ◽

Cited By ~ 28

Author(s):

J. S. Puskin ◽

Y. Yang

Keyword(s):

Lung Cancer ◽

Relative Risk ◽

Cancer Mortality ◽

Risk Model ◽

Lung Cancer Mortality ◽

Relative Risk Model

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Lung Cancer Attributable to Indoor Radon Exposure in France: Impact of the Risk Models and Uncertainty Analysis

Environmental Health Perspectives ◽

10.1289/ehp.9070 ◽

2006 ◽

Vol 114 (9) ◽

pp. 1361-1366 ◽

Cited By ~ 62

Author(s):

Olivier Catelinois ◽

Agnès Rogel ◽

Dominique Laurier ◽

Solenne Billon ◽

Denis Hemon ◽

...

Keyword(s):

Lung Cancer ◽

Uncertainty Analysis ◽

Indoor Radon ◽

Risk Models ◽

Radon Exposure

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The relative risk of mortality to the population on the Krasnoyarsk in the period when the air quality standards are exceeded

10.25743/sdm.2021.96.48.050 ◽

2021 ◽

Author(s):

D.A. Chernykh ◽

E.N. Bel’skaia ◽

O.V. Taseiko

Keyword(s):

Particulate Matter ◽

Relative Risk ◽

Air Quality ◽

Mortality Rate ◽

Risk Model ◽

Quality Standards ◽

Relative Increase ◽

Risk Of Mortality ◽

The City ◽

Relative Risk Model

A study was carried out to assess the effect of concentrations of particulate matter (PM10), nitrogen dioxide (NO2) and formaldehyde (F) exceeding the MPC on the mortality rate of the population of the city of Krasnoyarsk for 10 years (from 2000 to 2004 and from 2014 to 2018). The relative increase in mortality from exposure to the pollutants under study was determined using the relative risk model.

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A retrospective look at Rn-induced lung cancer mortality from the viewpoint of a relative risk model

Lung Cancer ◽

10.1016/0169-5002(89)90288-2 ◽

1989 ◽

Vol 5 ◽

pp. 4

Keyword(s):

Lung Cancer ◽

Relative Risk ◽

Cancer Mortality ◽

Risk Model ◽

Lung Cancer Mortality ◽

Relative Risk Model

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The bystander effect model of Brenner and Sachs fitted to lung cancer data in 11 cohorts of underground miners, and equivalence of fit of a linear relative risk model with adjustment for attained age and age at exposure

Journal of Radiological Protection ◽

10.1088/0952-4746/24/3/003 ◽

2004 ◽

Vol 24 (3) ◽

pp. 243-255 ◽

Cited By ~ 15

Author(s):

M P Little

Keyword(s):

Lung Cancer ◽

Relative Risk ◽

Bystander Effect ◽

Risk Model ◽

Cancer Data ◽

Lung Cancer Data ◽

Effect Model ◽

Relative Risk Model ◽

Age At Exposure

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Risk of lung cancer from radon exposure: contribution of recently published studies of uranium miners

Annals of the ICRP ◽

10.1016/j.icrp.2012.06.033 ◽

2012 ◽

Vol 41 (3-4) ◽

pp. 368-377 ◽

Cited By ~ 18

Author(s):

M. Tirmarche ◽

J. Harrison ◽

D. Laurier ◽

E. Blanchardon ◽

F. Paquet ◽

...

Keyword(s):

Lung Cancer ◽

Absolute Risk ◽

Epidemiological Studies ◽

Joint Analysis ◽

Radiological Protection ◽

Risk Models ◽

Radon Exposure ◽

Asian Populations ◽

Uranium Miners ◽

Background Mortality

The International Commission on Radiological Protection (ICRP) recently estimated the risk of lung cancer associated with radon exposure, and a statement was issued in ICRP Publication 115. This was based on recent epidemiological studies and the results from a joint analysis of cohorts of Czech, French, and German uranium miners, and indicated that the excess relative risk of lung cancer per unit of exposure should be expressed with consideration of chronic exposure over more than 10 years, by modelling time since median exposure, age attained or age at exposure, and taking in account, if possible, interaction between radon and tobacco. The lifetime excess absolute risk (LEAR) calculated from occupational exposure studies is close to 5 × 10−4 per working level month (WLM) (14 × 10−5 per hm J/m3). LEAR values estimated using risk models derived from both miners and domestic exposure studies are in good agreement after accounting for factors such as sex, attained age, and exposure scenario. A sensitivity analysis highlighted the high dependence of background mortality rates on LEAR estimates. Using lung cancer rates among Euro-American males instead of the ICRP reference rates (males and females, and Euro-American and Asian populations), the estimated LEAR is close to 7 × 10−4 per WLM (20 × 10−5 per hm J/m3).

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