Assessment of the mineral density and mineral content of the equine third metacarpal and first phalanx bone by dual energy x-ray absorptiometry

2010 ◽  
Vol 58 (3) ◽  
pp. 317-329 ◽  
Author(s):  
Péter Tóth ◽  
Csaba Horváth ◽  
Viktória Ferencz ◽  
Krisztina Nagy ◽  
Noémi Gligor ◽  
...  
Keyword(s):  
Bone Mineral ◽  
Mineral Content ◽  
Dual Energy ◽  
Mineral Density ◽  
X Ray ◽  
Number Of Patients ◽  
Metacarpal Bones ◽  
The Difference ◽  
The Individual ◽  
The Right

In the first part of this methodological study eleven metacarpi of 9 skeletally normal horses were examined from 4 directions by dual energy x-ray absorptiometry (DXA). The differences between the dorsopalmar-palmarodorsal and lateromedial-mediolateral (opposite sites) bone mineral density (BMD) values were found to be nonsignificant. In the second part of the study the precision of the Norland XR-26 densitometer was tested by measuring 34 metacarpal bones and 34 proximal phalanges, each of them three times, from a single direction. The difference between the individual measurements of the first phalanges and of the metacarpal bones originating from the right or the left side of the same horse were not significant, nor did the age or breed have a significant effect on BMD or bone mineral content (BMC). However, both BMD and BMC are greater in the metacarpal bones than in the proximal phalanges and are higher in geldings than in mares or to stallions, while the BMD or BMC values of mares and stallions did not differ from each other significantly. These data point to the necessity of further BMD studies in a higher number of patients.

scholarly journals Bone Mineral Density Changes in Patients with Recent-Onset Rheumatoid Arthritis

2011 ◽  
Vol 4 ◽  
pp. CMAMD.S7773 ◽  
Author(s):  
Eman A. Hafez ◽  
Howaida E. Mansour ◽  
Sherin H. Hamza ◽  
Sherine George Moftah ◽  
Takwa Badr Younes ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Dual Energy ◽  
Mineral Density ◽  
X Ray ◽  
Recent Onset ◽  
Das 28 ◽  
Radiological Damage ◽  
The Difference

Background Osteoporosis and related fragility fractures are one of the most common complications seen in patients with rheumatoid arthritis (RA) and dramatically affect quality of life. Objective To evaluate changes in bone mineral density in patients with recent onset rheumatoid arthritis (< 1 year) and its correlation if any with a modified DAS-28 score and simple erosion narrowing score (SENS). Methods This study included 30 patients with recent-onset rheumatoid arthritis fulfilling the new American College of Rheumatology/European League Against Rheumatism diagnostic criteria for rheumatoid arthritis and 20 healthy volunteers as controls. All were subjected to a complete blood count, erythrocyte sedimentation rate, C-reactive protein, liver function tests, renal function tests, rheumatoid factor, and plain x-rays of the hands and feet. Dual-energy x-ray absorptiometry DEXA was used to measure bone mineral density (BMD) of the left proximal femur, lumbar spine (L1–L4), and lower distal radius at the time of recruitment. Results In the RA patients, 13.3% had osteoporosis, 50% had osteopenia, and 36.7% had normal BMD. The most common site of osteoporosis was the lumbar spine (four patients, 13.3%) followed by the femur (two patients, 6.6%), and forearm (only one patient, 3.3%). There was a significantly higher percentage of osteoporosis among RA males than females and the difference was statistically significant ( P = 0.009). Osteoporosis was more common in patients treated with corticosteroids and disease modifying antirheumatic drugs (DMARDs) than in patients treated with only nonsteroidal anti-inflammatory drugs ( P = 0.004). Higher disease activity (DAS-28) was found in RA patients with osteoporosis compared to RA patients with normal BMD or osteopenia, but the difference was not statistically significant. Osteoporotic RA patients were found to have a higher SENS score for radiological damage than nonosteoporotic ones. Conclusion BMD changes do occur in patients with early RA, and are not necessarily correlated with disease activity (DAS-28). However, a significant negative correlation was found between BMD and the score of radiological damage (SENS). Dual energy x-ray absorptiometry is an important investigation to assess BMD in early RA patients.

scholarly journals AB0609 RADIOFREQUENCY ECHOGRAPHIC MULTI-SPECTROMETRY FOR THE ASSESSMENT OF BOTH FEMORA IN PREGNANT WOMEN

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1340.1-1340
Author(s):  
E. Kirilova ◽  
N. Kirilov ◽  
S. Vladeva
Keyword(s):  
Bone Mineral Density ◽  
Femoral Neck ◽  
Pregnant Women ◽  
Bone Mineral ◽  
Dual Energy ◽  
Z Score ◽  
Mineral Density ◽  
X Ray ◽  
The Mean ◽  
The Right

Background:Radiofrequency Echographic Multi-Spectrometry (REMS) is a non-ionizing innovative approach for the assessment of REMS-based bone mineral density (BMD) of the axial skeleton. The principle of the REMS technology is based on the analysis of native raw unfiltered ultrasound signals during an echographic scan of the lumbar spine or the femoral neck [1]. Several studies demonstrated the high concordance with dual energy X-ray absorptiometry (DXA) in terms of measured BMD with this novel technology [2,3]. In previous published literature it was envisaged to apply this technology for the examination of the axial bone density in pregnant women. Pregnancy-associated bone loss has been demonstrated as decreased bone mineral density (BMD) in previous studies [4].Objectives:The aim of the current study is to compare the BMD values of both femora between pregnant and non-pregnant women matched for age and BMI using the novel REMS technology.Methods:Of total fifty women twenty pregnant women (40%) and thirty non-pregnant women (60%) were included in the study. The mean age of the pregnant women was 32 years ± 5 standard deviations (SD), (range 25-41 years) and the mean age of the non-pregnant women was 30 years ± 6 standard deviations (SD), (range 24-39 years). REMS approach was used to assess REMS-based BMD and REMS-based Z-score values of the femoral neck. Furthermore, body mass index (BMI) and gestational age in weeks were evaluated.Results:The mean BMI of the pregnant women was 26 kg/m2 ± 7 kg/m2 (range 14 kg/m2-42 kg/m2) and those of the non-pregnant women was 25 kg/m2 ± 5 kg/m2 (range 16 kg/m2-35 kg/m2). The mean gestational age was 20 weeks’ gestation ± 5 weeks’ gestation (range 13-27 weeks’ gestation). REMS-based mean BMD of the left femoral neck of the pregnant women was 0.793 g/cm2 ± 0.167 g/cm2 (range 0.563 g/cm2-1.154 g/cm2). REMS-based mean BMD of the right femoral neck of the pregnant women was 0.828 g/cm2 ± 0.153 g/cm2 (range 0.570 g/cm2-1.161 g/cm2). After comparing left femoral neck BMD with the right femoral neck BMD of the pregnant women, we found a linear correlation (R=0.764). Left femoral neck BMD value (0.793 g/cm2) of the pregnant women was significantly lower than those of the non-pregnant women (0.854 g/cm2), p=0.002. The mean left femoral Z-score of the pregnant women (-0.1 SD with range -2.5 SD-2.9 SD) was also significantly lower compared to those of the non-pregnant women (1.2 SD with range -1.5 SD-3.1 SD), p=0.003.Conclusion:This is the first study which provides data about BMD and Z-score values of both femora in pregnant women assessed with the radiation-free REMS technology. Pregnant women demonstrated significantly lower femoral neck BMD values and Z-scores compared to those of the non-pregnant women. Innovative REMS method could be very helpful for making decision about the treatment of pregnant women who are at risk of lower BMD due to concomitant diseases and/or treatment associated with osteoporosis.References:[1]Casciaro S, Conversano F, Pisani P, Muratore M. New perspectives in echographic diagnosis of osteoporosis on hip and spine. Clin Cases Miner Bone Metab. 2015; 12(2):142-150.[2]Nikolov M, Nikolov N. AB0908 Assessment of the impact of the lean mass with body composition by dual-energy x-ray absorptiometry on the bone mineral density. Annals of the Rheumatic Diseases 2020; 79:1756.[3]Chakova M., Chernev D., Kashukeeva P., Krustev P., Abedinov F. Lumbar Sympathectomy - Literature Review. International Journal of Science and Research (IJSR) Volume 7 Issue 8, August 2018 ISSN (Online): 2319-7064.[4]Degennaro, V. A.; Cagninelli, G.; Lombardi, F. A. “VP34.12: First assessment of maternal status during pregnancy by means of radiofrequency echographic multi-spectrometry technology”. Ultrasound in Obstetrics & Gynecology. 2020, 56 (S1): 199.Disclosure of Interests:None declared.

scholarly journals Η επίδραση της διατροφής και της άσκησης στην κατάσταση των οστών σε παιδιά πρώτης σχολικής ηλικίας

2020 ◽  
Author(s):  
Θεόδωρος Σταμπουλής
Keyword(s):  
Bone Mineral ◽  
Mineral Content ◽  
Vigorous Physical Activity ◽  
Hierarchical Cluster ◽  
Dual Energy ◽  
Bone Area ◽  
Mineral Density ◽  
X Ray ◽  
Total Body ◽  
One Way Anova

Η βελτίωση της κατάστασης των οστών επηρεάζεται από τη διατροφή και την άσκηση, χωρίς ωστόσο να έχουν τεκμηριωθεί οι επιδράσεις τους σε παιδιά πρώτης σχολικής ηλικίας. Σκοπός της παρούσας διδακτορικής διατριβής ήταν η μελέτη της επίδρασης της διατροφής και της άσκησης στους δείκτες οστικής περιεκτικότητας (Bone Mineral Content, BMC), οστικής πυκνότητας (Bone Mineral Density, BMD) και οστικής επιφάνειας (Bone Area, BA) σε παιδιά πρώτης σχολικής ηλικίας. Στη μελέτη συμμετείχαν 208 προ-έφηβα παιδιά (ηλικία: 8.59±0.92 έτη, ύψος: 136.12±10.58cm, βάρος: 33.99±9.38kg, ΔΜΣ: 18.08±3.17kg/m2, Σωματικό Λίπος: 28.93±10.11%). τα οποία υποβλήθηκαν σε αξιολόγηση των δεικτών οστικής κατάστασης BMC, BMD και ΒΑ στο σύνολο του σώματος (Total Body Less Head, TBLH), στην οσφυϊκή μοίρα της σπονδυλικής στήλης (Lumbar Sipne 1-4, L1-L4), στο σύνολο του μηριαίου οστού (Total Femur, TF) και στον αυχένα του μηριαίου οστού (Femoral Neck, FN) τόσο στο κυρίαρχο (Dominant, D) όσο και στο μη κυρίαρχο κάτω άκρο (Νon Dominant, ND) με τη χρήση της μεθόδου απορροφησιομετριάς ακτίνων Χ διπλής ενέργειας (Dual energy X-ray Absorptiometry, DXA). Η διαιτητική πρόσληψη των μακρο- και μικροθρεπτικών συστατικών αξιολογήθηκε με τη χρήση ημερολογίου καταγραφής τροφίμων, τα οποία αναλύθηκαν με τη χρήση του Science Fit Diet 200A. Για τον αντικειμενικό προσδιορισμό της άσκησης, ως σύνολο της ημερήσιας μέτριας προς έντονης φυσικής δραστηριότητας (moderate-to-vigorous physical activity, MVPA), πραγματοποιήθηκε καταγραφή της για 7 συνεχόμενες μέρες με τη χρήση επιταχυνσιομέτρου ActiGraph GT3X+. Για την ομαδοποίηση των παιδιών στις ομάδες συνδυασμού άσκησης και διατροφής και στις ομάδες διατροφής χρησιμοποιήθηκε η Ιεραρχική Ανάλυση Ομαδοποίησης (Hierarchical Cluster Analysis) και για την ομαδοποίηση των ομάδων άσκησης χρησιμοποιήθηκε η τεχνική ομαδοποίησης visual binning. Οπότε προέκυψαν οι ομάδες συνδυαστικής επίδρασης διατροφής κι άσκησης Α και Β, οι διατροφικές ομάδες χαμηλής πρόσληψης (ΧΠ), μέτριας πρόσληψης (ΜΠ) και υψηλής πρόσληψης (ΥΠ) των θρεπτικών συστατικών σχετικών με την οστική κατάσταση (πρωτεΐνη, ασβέστιο, βιταμίνη D και φώσφορος) και οι ισόποσες ομάδες άσκησης 1,2 και 3. Για την ανάλυση των επιδράσεων χρησιμοποιήθηκε η ανάλυση διακύμανσης ως προς έναν παράγοντα (One-Way ANOVA). Τα αποτελέσματα έδειξαν ότι η ομάδα Β είχε σημαντικά υψηλότερη διαφορά με την ομάδα Α στο δείκτη BMD του TF και FN τόσο στο D όσο και στο ND (p<0.005), με επιπλέον υψηλότερη διαφορά στο δείκτη BMC του FN του ND (p<0.05). Η ομάδα ΥΠ είχε σημαντικά υψηλότερες διαφορές στο δείκτη BMD του TF και FN τόσο του D όσο και του ND (p<0.05) με την ομάδα ΧΠ. Αναφορικά με την επίδραση της άσκησης, η ομάδα 3 είχε σημαντικά υψηλότερες διαφορές την ομάδα 1 στο δείκτη BMD του TF τόσο στο D όσο και στο ND, και στο FN του ND (p<0.05). Δεν εντοπίστηκαν σημαντικές διαφοροποιήσεις στο TBLH και στην L1-L4 σε κάποιο από του δείκτες BMC, BMD και ΒΑ. Συμπερασματικά, η συνδυαστική επίδραση διατροφής και άσκησης βελτίωσε BMD και BMC στα κάτω άκρα, η διατροφή βελτίωσε μόνο το δείκτη BMD στα κάτω άκρα ενώ η άσκηση επέδρασε κυρίως στο BMD του ND.

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