Restless legs syndrome: the most prevalent “unknown” disorder

2011 ◽  
Vol 152 (7) ◽  
pp. 259-266 ◽  
Author(s):  
Anett Lindner ◽  
Márta Novák ◽  
Miklós Zsolt Molnár
Keyword(s):  
Restless Legs Syndrome ◽  
Health Care Professionals ◽  
Clinical Presentation ◽  
Social Consequences ◽  
Sleep Disruption ◽  
Daytime Functioning ◽  
Restless Legs ◽  
High Prevalence ◽  
Consequences Of Disease

Sleep disorders are also considered as significant chronic disorders, as their physiological and psycho-social consequences are well documented. Restless legs syndrome has high prevalence, as it occurs in 5–10 % of the general population. Since clinical presentation is not well appreciated by many of the health care professionals, only a small proportion of the patients with restless legs syndrome is diagnosed and treated. The consequences of disease, however, are not negligible. The majority of the patients suffer from insomnia, impaired daytime functioning and quality of life. Although, restless legs syndrome is frequently characterized as a sleep disorder, it does not only influence sleep but also the daytime functioning of the patients. Additionally, restless legs syndrome causes not only subjective complaints and sleep disruption, but it is also associated with cardiovascular disorders. Orv. Hetil., 2011, 152, 259–266.

The Impact of Restless Legs Syndrome/ Willis–Ekbom Disorder on Quality of Life

2013 ◽  
Vol 8 (2) ◽  
pp. 97 ◽  
Author(s):  
Aadi Kalloo ◽  
Charlene E Gamaldo ◽  
Anthony B Kwan ◽  
Rachel E Salas ◽  
◽  
...  
Keyword(s):  
Quality Of Life ◽  
Restless Legs Syndrome ◽  
Sleep Disruption ◽  
Iron Supplements ◽  
Prevalence Studies ◽  
Adverse Side Effects ◽  
Restless Legs ◽  
The Us ◽  
The Impact

Restless legs syndrome (RLS), also known as Willis–Ekbom Disorder (WED), is a condition associated with nocturnal sensorimotor symptoms that can result in significant sleep disruption. RLS is a prevalent condition, affecting an estimated 3.9–14.3 % of the US population. Despite the most recently reported prevalence studies, many experts in the field still believe RLS is a generally underdiagnosed condition. RLS can negatively affect a patient’s quality of life (QoL) across several domains, such as daytime sleepiness, decreased general health, decreased immune function, stress and mood. Of those patients with moderate-to-severe symptoms that require treatment, the currently available therapeutic options (e.g. iron supplements, dopamine agonists, benzodiazepines, opioids and anticonvulsants) can also come with adverse side effects that can further impact QoL. The purpose of this article is to examine the QoL deficits experienced by RLS patients.

The Impact of Restless Legs Syndrome/Willis-Ekbom Disorder on Quality of Life

US Neurology ◽  
2014 ◽  
Vol 10 (01) ◽  
pp. 15
Author(s):  
Aadi Kalloo ◽  
Charlene E Gamaldo ◽  
Anthony B Kwan ◽  
Rachel E Salas ◽  
◽  
...  
Keyword(s):  
Quality Of Life ◽  
Restless Legs Syndrome ◽  
Sleep Disruption ◽  
Iron Supplements ◽  
Prevalence Studies ◽  
Adverse Side Effects ◽  
Restless Legs ◽  
The Us ◽  
The Impact

Restless legs syndrome (RLS), also known as Willis–Ekbom Disorder (WED), is a condition associated with nocturnal sensorimotor symptoms that can result in significant sleep disruption. RLS is a prevalent condition, affecting an estimated 3.9–14.3 % of the US population. Despite the most recently reported prevalence studies, many experts in the field still believe RLS is a generally underdiagnosed condition. RLS can negatively affect a patient’s quality of life (QoL) across several domains, such as daytime sleepiness, decreased general health, decreased immune function, stress, and mood. Of those patients with moderate-to-severe symptoms that require treatment, the currently available therapeutic options (e.g. iron supplements, dopamine agonists, benzodiazepines, opioids, and anticonvulsants) can also come with adverse side effects that can further impact QoL. The purpose of this article is to examine the QoL deficits experienced by RLS patients.

The Relationship between Restless Legs Syndrome and Quality of Life in Patients with Myasthenia Gravis

2019 ◽  
Vol 81 (3-4) ◽  
pp. 205-208
Author(s):  
Monica F. Ataide ◽  
Carolina da Cunha-Correia ◽  
Katia C.L. Petribú
Keyword(s):  
Quality Of Life ◽  
Myasthenia Gravis ◽  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Restless Legs ◽  
Study Population ◽  
Clinical Conditions

Background: Restless legs syndrome (RLS) is characterized for an uncomfortable sensation in legs and an irresistible desire to move them. This disorder has been more recently recognized in patients with myasthenia gravis (MG) and can interfere with the quality of life (QOL). Objectives: The aims of this study are to describe the prevalence of RLS and its severity and influence on the QOL in patients with MG. Method: This was a cross-sectional study conducted from May to June 2016 in Recife, Brazil. A sample of 42 patients was interviewed using a sociodemographic questionnaire, MG QOL questionnaire-15 and The RLS Rating Scale. Results: RLS was present in 47.6% of patients and of these 40.5% met moderate to severe RLS criteria. Patients were 45 years on average (SD ± 14.4) and women represented 57.1% of the study population. Among patients with RSL, the quality-of-life scores were worse (p = 0.010) on average. There was no association of RLS with the duration of MG, use of immunosuppressant or clinical conditions that could mimic the occurrence of RLS. Conclusion: RLS is a prevalent condition in patients with MG, and may be severe enough to negatively impact QOL.

P0019 Effect of pramipexole on quality of life in restless legs syndrome: results spanning 9 months

2007 ◽  
Vol 8 ◽  
pp. S74
Author(s):  
C. Trenkwalder ◽  
K. Stiasny-Kolster ◽  
A. Kupsch ◽  
W. Oertel ◽  
J. Koester
Keyword(s):  
Quality Of Life ◽  
Restless Legs Syndrome ◽  
Restless Legs

Restless leg syndrome in adult patients with β-thalassemia major

2021 ◽  
Vol 74 (7-8) ◽  
pp. 266-272
Author(s):  
Ramazan Erdem ◽  
Nazan Şimşek Erdem ◽  
Erdal Kurtoğlu
Keyword(s):  
Sleep Quality ◽  
Restless Legs Syndrome ◽  
Excessive Daytime Sleepiness ◽  
Daytime Sleepiness ◽  
Thalassemia Major ◽  
Adult Patients ◽  
Poor Sleep ◽  
Poor Sleep Quality ◽  
Restless Legs

To investigate the quality of sleep and the presence of Restless Legs Syndrome (RLS) in the Turkish population with β-thalassemia major (TM). The second aim was to assess the risk factors of RLS in TM adults. The study sample comprised of 121 patients at least 18 years old with TM. The patients’ socio-demographic information, body mass indexes (BMI), current medications, laboratory data were recorded. The patients were asked if they had a history of chronic kidney disease, diabetes mellitus (DM), and polyneuropathy. Restless legs syndrome was diagnosed according to the International Restless Legs Syndrome Study Group criteria. The sleep quality of the patients was assessed using the Pittsburgh Sleep Quality Index (PSQI) scale. The Epworth Sleepiness Scale (ESS) was used to assess excessive daytime sleepiness in the patients. The median age of the patients was 25 years (range 18-52). The mean BMI was 21.49±2.5 (R 14-26.5) for all patients. The prevalence of RLS was 5% in TM adult patients. The TM patients with RLS had no major complications of TM. The median PSQI global score of all patients was 3. Twenty-two (18.1%) patients had poor sleep quality. The reason for poor sleep quality was RLS symptoms in four patients (18%). There was no significant association between PSQI total score and blood parameters of the patients. Twelve (9.9%) patients had ESS scores greater than 10, which indicates excessive daytime sleepiness. The prevalence of RLS in TM patients was similar to that of the general Turkish adult population. These results indicate that RLS may occur in patients with TM, although they had a high level of serum ferritin.

High Prevalence Of Restless Legs Syndrome Symptoms In Liver Cirrhosis Patients

2012 ◽  
Author(s):  
Hamdan AL-Jahdali ◽  
Abdullah AlEnezi ◽  
Ahmed BaHammam ◽  
Abulrahman ALjumah ◽  
Salim Baharoon ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Restless Legs Syndrome ◽  
Restless Legs ◽  
High Prevalence
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