Simulation of Nanotube Deposition in the Human Respiratory Tract

2014 ◽  
Vol 2014 (1) ◽  
pp. 8-20 ◽  
Author(s):  
Robert Sturm ◽  
AIHAJ ◽  
1979 ◽  
Vol 40 (12) ◽  
pp. 1055-1066 ◽  
Author(s):  
E. AUSTIN ◽  
J. BROCK ◽  
E. WISSLER

Author(s):  
Digamber Singh

The human respiratory tract has a complex airflow pattern. If any obstruction is present in the airways, it will change the airflow pattern and deposit particles inside the airways. This is the concern of breath quality (inspired air), and it is decreasing due to the unplanned production of material goods. This is a primary cause of respiratory illness (asthma, cancer, etc.). Therefore, it is important to identify the flow characteristics in the human airways and airways with a glomus tumour with particle deposition. A numerical diagnosis is presented with an asymmetric unsteady-state light breathing condition (10 l/min). An in vitro human respiratory tract model has been reconstructed using computed tomography scan techniques and an artificial glomus tumour developed 2 cm above a carina on the posterior wall of the trachea. The transient flow characteristics are numerically simulated with a realizable (low Reynolds number) k–ɛ turbulence model. The flow disturbance is captured around the tumour, which influenced the upstream and downstream of the flow. The flow velocity pattern, wall shear stress and probable area of inflammation (hotspot) due to suspended particle deposition are determined, which may assist doctors more effectively in aerosol therapy and prosthetics of human airways illness.


2004 ◽  
Vol 86 (4) ◽  
pp. 337-352 ◽  
Author(s):  
Eduardo B. Farfán ◽  
Eun Young Han ◽  
Wesley E. Bolch ◽  
ChulHaeng Huh ◽  
Thomas E. Huston ◽  
...  

1986 ◽  
Vol 108 (1) ◽  
pp. 19-27 ◽  
Author(s):  
L. M. Hanna ◽  
P. W. Scherer

A steady-state, one-dimensional theoretical model of human respiratory heat and water vapor transport is developed. Local mass transfer coefficients measured in a cast replica of the upper respiratory tract are incorporated into the model along with heat transfer coefficients determined from the Chilton-Colburn analogy and from data in the literature. The model agrees well with reported experimental measurements and predicts that the two most important parameters of the human air-conditioning process are: 1) the blood temperature distribution along the airway walls, and 2) the total cross-sectional area and perimeter of the nasal cavity. The model also shows that the larynx and pharynx can actually gain water over a respiratory cycle and are the regions of the respiratory tract most subject to drying. With slight modification, the model can be used to investigate respiratory heat and water vapor transport in high stress environments, pollutant gas uptake in the respiratory tract, and the connection between respiratory air-conditioning and the function of the mucociliary escalator.


2012 ◽  
Vol 18 (9) ◽  
pp. 1538-1539 ◽  
Author(s):  
Saskia L. Smits ◽  
Marije van Leeuwen ◽  
Claudia M.E. Schapendonk ◽  
Anita C. Schürch ◽  
Rogier Bodewes ◽  
...  

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