scholarly journals Nonhealing, progressive stress fractures of the foot in a 13-year-old basketball player: is vitamin K deficiency a risk factor?

2017 ◽  
Vol 29 (4) ◽  
pp. 763-766
Author(s):  
Meral Bayramoğlu ◽  
Nuray Ünlütürk
The Lancet ◽  
2001 ◽  
Vol 357 (9273) ◽  
pp. 1995-1996 ◽  
Author(s):  
Pawel Szulc ◽  
Pierre Jean Meunier

2009 ◽  
Vol 76 (1) ◽  
pp. 18-22 ◽  
Author(s):  
Thilo Krueger ◽  
Ralf Westenfeld ◽  
Markus Ketteler ◽  
Leon J. Schurgers ◽  
Jürgen Floege

2010 ◽  
Vol 51 (6) ◽  
pp. 773-776 ◽  
Author(s):  
PM van Hasselt ◽  
W de Vries ◽  
E de Vries ◽  
K Kok ◽  
ECM Cranenburg ◽  
...  

Author(s):  
Najwan K. Fakhree ◽  
Sarah H. Mhaibes ◽  
Heba H. Khalil

Vitamins k is an important fat-soluble vitamin that can be obtained from plants, bacteria and animals and is necessary for the blood clotting. It plays a key function as a cofactor in the synthesizing of blood clotting proteins in the liver; recently, the interest for its functions in extra-hepatic tissue has increased. Vitamin k deficiency is usually caused by abnormal absorption rather than in the lack of vitamin in food. Apart from its impact on clotting, chronic subclinical deficiency of vitamin K maybe a risk factor for many diseases such as osteoporosis, atherosclerosis, cancer, insulin resistance, neurodegenerative diseases and others, while current food intake guidelines be focused on the daily dose necessary to avoid blood loss. Several researchers found out that vitamin K needs may be substantially higher for certain health functions.


1988 ◽  
Vol 60 (01) ◽  
pp. 039-043 ◽  
Author(s):  
L Mandelbrot ◽  
M Guillaumont ◽  
M Leclercq ◽  
J J Lefrère ◽  
D Gozin ◽  
...  

SummaryVitamin K status was evaluated using coagulation studies and/ or vitamin IQ assays in a total of 53 normal fetuses and 47 neonates. Second trimester fetal blood samples were obtained for prenatal diagnosis under ultrasound guidance. Endogenous vitamin K1 concentrations (determined by high performance liquid chromatography) were substantially lower than maternal levels. The mean maternal-fetal gradient was 14-fold at mid trimester and 18-fold at birth. Despite low vitamin K levels, descarboxy prothrombin, detected by a staphylocoagulase assay, was elevated in only a single fetus and a single neonate.After maternal oral supplementation with vitamin K1, cord vitamin K1 levels were boosted 30-fold at mid trimester and 60 fold at term, demonstrating placental transfer. However, these levels were substantially lower than corresponding supplemented maternal levels. Despite elevated vitamin K1 concentrations, supplemented fetuses and neonates showed no increase in total or coagulant prothrombin activity. These results suggest that the low prothrombin levels found during intrauterine life are not due to vitamin K deficiency.


1968 ◽  
Vol 20 (01/02) ◽  
pp. 078-087 ◽  
Author(s):  
H. C Hemker ◽  
A. D Muller

SummaryPIVKA, the circulating anticoagulant protein found in vitamin K deficiency can, on kinetical grounds, be recognized as an analogue of factor X. The existence of analogues of other vitamin K-dependent clotting factors cannot be ruled out, but need not be assumed to explain the experimental results.


2000 ◽  
Vol 76 (3) ◽  
pp. 233-6 ◽  
Author(s):  
Eugênio Grillo ◽  
Ronaldo José Melo da Silva ◽  
Jorge Humberto Barbato Filho

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