scholarly journals Should a family history of papillary thyroid carcinoma indicate more aggressive therapy in patients with this tumor?

2014 ◽  
Vol 58 (8) ◽  
pp. 812-816 ◽  
Author(s):  
Pedro Weslley Rosario ◽  
Maria Regina Calsolari

Objective To determine whether the currently recommended therapy for papillary thyroid carcinoma (PTC) that show no classical factors indicating a poor prognosis is also effective in cases with a family history of this tumor. Subjects and methods: Forty-two patients were studied; 10 were submitted to lobectomy and 32 to total thyroidectomy, including 23 without lymph node dissection and 9 with lymph node dissection. None of the patients received radioiodine or was maintained under TSH suppression. Results No case of recurrence was detected by imaging methods and there was no increase in thyroglobulin or antithyroglobulin antibodies during follow-up (24 to 72 months). Conclusion The treatment usually recommended for patients with PTC does not need to be modified in the presence of a family history of this tumor if no factors indicating a poor prognosis are present (tumor ≤2 cm, non-aggressive histology, no extensive extrathyroid invasion or important lymph node involvement, complete tumor resection, no evidence of persistent disease after surgery).

2013 ◽  
Vol 37 (7) ◽  
pp. 1584-1591 ◽  
Author(s):  
Romain Ducoudray ◽  
Christophe Trésallet ◽  
Gaelle Godiris-Petit ◽  
Frédérique Tissier ◽  
Laurence Leenhardt ◽  
...  

2011 ◽  
Vol 19 (3) ◽  
pp. 996-1000 ◽  
Author(s):  
Soo Youn Bae ◽  
Jung-Hyun Yang ◽  
Min-Young Choi ◽  
Jun-Ho Choe ◽  
Jung-Han Kim ◽  
...  

2007 ◽  
Vol 31 (10) ◽  
pp. 1954-1959 ◽  
Author(s):  
Yong Sang Lee ◽  
Seok Won Kim ◽  
Sun Wook Kim ◽  
Seok Ki Kim ◽  
Han-Sung Kang ◽  
...  

2019 ◽  
Vol 50 (4) ◽  
pp. 387-391 ◽  
Author(s):  
Tiantian Wang ◽  
Yanping Wu ◽  
Qiuping Xie ◽  
Haichen Yan ◽  
Xiaoming Zhou ◽  
...  

Abstract Background Remote access and endoscopic thyroid surgery has been gaining popularity because it allows patients to avoid a visible scar in the neck. There is limited data on transoral endoscopic thyroidectomy when it relates to patients with papillary thyroid carcinoma. We aim to evaluate the safety of ipsilateral central compartment dissection for patients who undergo transoral thyroidectomy (thyroidectomy vestibular approach–compartment lymph node dissection). Patients and Methods A total of 80 patients who underwent thyroidectomy vestibular approach–compartment lymph node dissection for papillary thyroid carcinoma from June 2015 to September 2016 were identified. Over the same period, a matched cohort of 80 patients who underwent open thyroidectomy with routine ipsilateral central compartment dissection was also identified (Open-compartment lymph node dissection). The two groups were analyzed in terms of patient characteristics, perioperative clinical results and post-operative outcomes. Results All patients were female with a mean age of 32-year. There was no difference in mean maximum tumor size and number of lymph nodes dissected. Moreover, there was no difference in average positive lymph nodes between thyroidectomy vestibular approach–compartment lymph node dissection and Open-compartment lymph node dissection (1.48 vs 1.08, P = 0.647). Operative time was longer in the thyroidectomy vestibular approach–compartment lymph node dissection group (193 vs 102 min, P < 0.001). Thyroidectomy specific complications were similar with rates of temporary recurrent laryngeal nerve palsy of 6.3 vs 8.8% and temporary hypocalcemia rates of 2.5 vs 5% in the thyroidectomy vestibular approach–compartment lymph node dissection and Open-compartment lymph node dissection groups, respectively. Conclusions Thyroidectomy vestibular approach–compartment lymph node dissection is a feasible and safe option for select patients with papillary thyroid carcinoma who require central node dissection compared with Open-compartment lymph node dissection, and can be a viable alternative for patients wishing to avoid a visible scar.


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