scholarly journals Restless legs syndrome/Willis-Ekbom disease in multiple sclerosis: a contributing factor for anxiety, disability, sleep disorder, and quality of life

2020 ◽  
Vol 78 (11) ◽  
pp. 708-712
Author(s):  
Meral Seferoğlu ◽  
Ali Özhan Sivaci ◽  
Abdulkadir Tunç
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Sleep Quality ◽  
Sleep Disorders ◽  
Functional Capacity ◽  
Restless Legs Syndrome ◽  
Symptom Severity ◽  
Restless Legs ◽  
Mental Hrqol

ABSTRACT Background: Restless legs syndrome (RLS) is one of the most common and burdensome sleep disorders in the course of multiple sclerosis (MS). Objective: To evaluate common MS-related symptoms and consequences between groups with and without RLS and further assess the association of quality of life determinants with RLS symptom severity. Methods: According to their RLS status, 46 relapsing-remitting MS patients were divided into MS-RLS+ (n=19) and MS-RLS- groups (n=27). Specific questionnaires were administered to assess the patients’ health-related quality of life (HRQoL), fatigue levels, sleep quality, daily sleepiness, anxiety, and depression symptoms. Functional capacity was examined using the Expanded Disability Status Scale (EDSS). Results: The prevalence of RLS was 41.3%. Compared to the MS-RLS- group, those with RLS had higher EDSS scores, more cranial and spinal lesions, longer disease duration, and were older. In the MS-RLS+ group, symptom severity scores were positively correlated with higher anxiety and poorer sleep quality. The symptom severity score was negatively correlated with mental HRQoL and pain scores. Conclusion: In conclusion, the findings of the current study indicate the negative impact of RLS on functional capacity, anxiety, sleep quality, and mental HRQoL of MS patients. Further studies using more accurate diagnostic strategies for identifying RLS and other sleep disorders are necessary to clarify the association of MS with RLS and explore relevant clinical implications.

scholarly journals The prevalence of common sleep disorders in young adults: a descriptive population-based study

SLEEP ◽  
2020 ◽  
Vol 43 (10) ◽  
Author(s):  
Nigel McArdle ◽  
Sarah V Ward ◽  
Romola S Bucks ◽  
Kathleen Maddison ◽  
Anne Smith ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Young Adults ◽  
Sleep Disorders ◽  
Sleep Disorder ◽  
Restless Legs Syndrome ◽  
Survey Methods ◽  
Apnea Hypopnea Index ◽  
Restless Legs ◽  
Obstructive Sleep

Abstract Sleep disorders in adults are associated with adverse health effects including reduced quality of life and increased mortality. However, there is little information on sleep disorders in young adults. A cross-sectional observational study was undertaken in 1,227 young adults participating in the Western Australian Pregnancy (Raine) Study (2012–2014) to describe the prevalence of common sleep disorders. In-laboratory polysomnography (PSG) and validated survey methods were used, including the Epworth Sleepiness Scale, Pittsburgh Sleep Symptom Questionnaire-Insomnia, and International Restless Legs Syndrome Study Group criteria. A total of 1,146 participants completed a core questionnaire, 1,051 completed a sleep-focused questionnaire and 935 had analyzable PSG data. Participants had a mean age of 22.2 years and female to male ratio of 1.1 to 1. The respective sleep disorder prevalences in females and males were: obstructive sleep apnea (OSA) (apnea-hypopnea index [AHI]: ≥5 events/hour) 14.9% (95% CI: 11.8–18.5) and 26.9% (95% CI: 22.9–31.2); chronic insomnia, 19.3% (95% CI: 16.7–23.9) and 10.6% (95% CI: 8.3–13.9); restless legs syndrome, 3.8% (95% CI: 2.4–5.6) and 1.9% (95% CI: 0.9–3.4); and abnormal periodic leg movements during sleep (>5 movements/hour), 8.6% (95% CI: 6.3–11.5) and 9.6% (95% CI: 7.1–12.7). There were statistically significant differences in prevalence between sexes for OSA and insomnia, which persisted after adjustment for body mass index and education. In those with complete data on all sleep-related assessments (n = 836), at least one sleep disorder was present in 41.0% of females and 42.3% of males. Sleep disorders are very common in young adults. Health practitioners should be aware of these high prevalences, as early identification and treatment can improve quality of life and may reduce later morbidity and mortality.

scholarly journals 0662 Restless Legs Syndrome And Health-related Quality Of Life In Adults With Multiple Sclerosis

SLEEP ◽  
2019 ◽  
Vol 42 (Supplement_1) ◽  
pp. A264-A264
Author(s):  
Katie L Cederberg ◽  
Brenda Jeng ◽  
Jeffer E Sasaki ◽  
Tiffany J Braley ◽  
Arthur S Walters ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Restless Legs Syndrome ◽  
Health Related Quality ◽  
Restless Legs ◽  
Related Quality ◽  
Health Related

scholarly journals Restless legs syndrome and health‐related quality of life in adults with multiple sclerosis

2019 ◽  
Vol 29 (3) ◽  
Author(s):  
Katie L. J. Cederberg ◽  
Brenda Jeng ◽  
Jeffer E. Sasaki ◽  
Tiffany J. Braley ◽  
Arthur S. Walters ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Restless Legs Syndrome ◽  
Health Related Quality ◽  
Restless Legs ◽  
Related Quality ◽  
Health Related

scholarly journals 0615 The Prevalence of Common Sleep Disorders In Young Adults: A Population-Based Study

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A235-A236
Author(s):  
P R Eastwood ◽  
S V Ward ◽  
R S Bucks ◽  
K Maddison ◽  
A Smith ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Young Adults ◽  
Sleep Disorders ◽  
Restless Legs Syndrome ◽  
Survey Methods ◽  
Cross Sectional ◽  
Female Ratio ◽  
Periodic Leg Movements ◽  
Restless Legs

Abstract Introduction Adult sleep disorders are associated with adverse health effects including reduced quality of life and increased mortality. However, there is a paucity of data on sleep disorders in young adulthood. Methods We undertook a cross-sectional observational study of 1,227 young adults participating in the Western Australian Pregnancy (Raine) Study (2012-2014) to describe the prevalence of common sleep disorders in young adults. We used in-laboratory polysomnography (PSG) and validated survey methods, including the Epworth Sleepiness Scale (ESS), Pittsburgh Sleep Symptom Questionnaire-Insomnia and International Restless Legs Syndrome Study Group criteria. 1,146 completed a core questionnaire, 1,051 completed a sleep-focused questionnaire and 935 had analysable PSG data. Results Participants had a mean age of 22.2 years and male to female ratio of 1 to 1.1. The prevalence of OSA [apnoea hypopnoea index (AHI): ≥5events/hour] was 20.8% (95%CI: 18.2 to 23.6) and this was usually of mild severity (AHI:≥5 to<15events/hour, 17.1%). OSA syndrome (AHI≥5 events/hour and ESS≥11) was found in 2.8% (95%CI: 1.9 to 4.1). Chronic insomnia was present in 16.6% (95%CI: 14.7 to 19.4). Restless legs syndrome was present in 2.9% (95%CI: 2.0 to 4.0) and abnormal periodic leg movements during sleep (>5 movements/hour) in 9.1% (95%CI: 7.3 to 11.1). In those participants who had complete data on all sleep-related assessments (n=841), at least one sleep disorder was present in 42.6%. Conclusion Sleep disorders are very common in young adults. Health practitioners should be aware of these high prevalences, as early identification and treatment can improve quality of life and may reduce later morbidity and mortality. Support  

Restless legs syndrome is associated with poor sleep quality and quality of life in patients with ankylosing spondylitis: a questionnaire-based study

2015 ◽  
Vol 116 (3) ◽  
pp. 329-336 ◽  
Author(s):  
Seden Demirci ◽  
Kadir Demirci ◽  
Atalay Doğru ◽  
Esra Erkol İnal ◽  
Hasan Rifat Koyuncuoğlu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Ankylosing Spondylitis ◽  
Sleep Quality ◽  
Restless Legs Syndrome ◽  
Poor Sleep ◽  
Poor Sleep Quality ◽  
Restless Legs

The Relationship between Restless Legs Syndrome and Quality of Life in Patients with Myasthenia Gravis

2019 ◽  
Vol 81 (3-4) ◽  
pp. 205-208
Author(s):  
Monica F. Ataide ◽  
Carolina da Cunha-Correia ◽  
Katia C.L. Petribú
Keyword(s):  
Quality Of Life ◽  
Myasthenia Gravis ◽  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Restless Legs ◽  
Study Population ◽  
Clinical Conditions

Background: Restless legs syndrome (RLS) is characterized for an uncomfortable sensation in legs and an irresistible desire to move them. This disorder has been more recently recognized in patients with myasthenia gravis (MG) and can interfere with the quality of life (QOL). Objectives: The aims of this study are to describe the prevalence of RLS and its severity and influence on the QOL in patients with MG. Method: This was a cross-sectional study conducted from May to June 2016 in Recife, Brazil. A sample of 42 patients was interviewed using a sociodemographic questionnaire, MG QOL questionnaire-15 and The RLS Rating Scale. Results: RLS was present in 47.6% of patients and of these 40.5% met moderate to severe RLS criteria. Patients were 45 years on average (SD ± 14.4) and women represented 57.1% of the study population. Among patients with RSL, the quality-of-life scores were worse (p = 0.010) on average. There was no association of RLS with the duration of MG, use of immunosuppressant or clinical conditions that could mimic the occurrence of RLS. Conclusion: RLS is a prevalent condition in patients with MG, and may be severe enough to negatively impact QOL.

P0019 Effect of pramipexole on quality of life in restless legs syndrome: results spanning 9 months

2007 ◽  
Vol 8 ◽  
pp. S74
Author(s):  
C. Trenkwalder ◽  
K. Stiasny-Kolster ◽  
A. Kupsch ◽  
W. Oertel ◽  
J. Koester
Keyword(s):  
Quality Of Life ◽  
Restless Legs Syndrome ◽  
Restless Legs
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