scholarly journals Hepatitis C in Hemodialysis Units: diagnosis and therapeutic approach

2019 ◽  
Vol 41 (4) ◽  
pp. 539-549
Author(s):  
Natasha Silva Constancio ◽  
Maria Lucia Gomes Ferraz ◽  
Carmen Tzanno Branco Martins ◽  
Angiolina Campos Kraychete ◽  
Paulo Lisboa Bitencourt ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
General Population ◽  
Horizontal Transmission ◽  
Review Article ◽  
The Other ◽  
Disease Eradication ◽  
Brazilian Society ◽  
Near Future

Abstract According to data from the last census of the Brazilian Society of Nephrology (SBN), the prevalence of hepatitis C virus (HCV) in Brazilian hemodialysis units (HU) is 3.3%, about three times higher than what is reported for the Brazilian general population. Often, professionals working in HU are faced with clinical situations that require rapid HCV diagnosis in order to avoid horizontal transmission within the units. On the other hand, thanks to the development of new antiviral drugs, the cure of patients with HCV, both in the general population and in patients with chronic kidney disease and the disease eradication, appear to be very feasible objectives to be achieved in the near future . In this scenario, SBN and the Brazilian Society of Hepatology present in this review article a proposal to approach HCV within HUs.

Prevalence of hepatitis C virus infection in the general population of northern Spain

2001 ◽  
Vol 13 (5) ◽  
pp. 477-481 ◽  
Author(s):  
Sabino Riestra ◽  
Eloy Fernández ◽  
Pilar Leiva ◽  
Sara García ◽  
Guillermo Ocio ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
General Population ◽  
Virus Infection ◽  
Hepatitis C Virus Infection ◽  
Northern Spain

Hepatitis C Virus Genotypes and Viral Concentrations in Participants of a General Population Survey in the United States

2006 ◽  
Vol 131 (2) ◽  
pp. 478-484 ◽  
Author(s):  
Omana V. Nainan ◽  
Miriam J. Alter ◽  
Deanna Kruszon-Moran ◽  
Feng-Xiang Gao ◽  
Guoliang Xia ◽  
...  
Keyword(s):  
United States ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
General Population ◽  
Population Survey ◽  
The United States ◽  
General Population Survey ◽  
Virus Genotypes ◽  
Hepatitis C Virus Genotypes

Progress in hepatitis C virus management in chronic kidney disease

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Abraham Cohen-Bucay ◽  
Jean M. Francis ◽  
Craig E. Gordon
Keyword(s):  
Chronic Kidney Disease ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Kidney Disease ◽  
Virus Management

scholarly journals The Unravelled Link between Chronic Kidney Disease and Hepatitis C Infection

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Fabrizio Fabrizi ◽  
Piergiorgio Messa ◽  
Paul Martin
Keyword(s):  
Chronic Kidney Disease ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Kidney Disease ◽  
Renal Disease ◽  
Chronic Renal Disease ◽  
World Health ◽  
Adjusted Relative Risk ◽  
Hepatitis C Infection ◽  
Increased Risk

The 2011 report of the World Health Organization General Assembly on noncommunicable diseases identified chronic kidney disease as a worldwide health issue posing a heavy economic burden. Hepatitis C virus infection, which is responsible for over 1 million deaths resulting from cirrhosis and liver cancer, is linked to chronic kidney disease in several ways; some forms of renal disease are precipitated by hepatitis C and patients with end-stage chronic renal disease are at increased risk for acquiring HCV. The aim of this review is to update the evidence on the relationship between hepatitis C infection and chronic kidney disease. Information has been accumulated in the last decade indicating that HCV plays an adverse effect on the incidence and progression of chronic kidney disease; a novel meta-analysis of observational studies (seven longitudinal studies; 890,560 unique individuals) found a relationship between hepatitis C seropositivity and incidence of reduced estimated glomerular filtration rate (adjusted relative risk, 1.70; 95% CI, 1.20; 2.39; P=0.002) in the adult general population. In addition to conventional risk factors, hepatitis C may be an additional factor for the development of chronic kidney disease, and an atheromasic activity of hepatitis C virus has been mentioned. The link between hepatitis C and atherosclerosis could also explain the excess risk of cardiovascular mortality that has been observed among hepatitis C virus seropositive patients undergoing maintenance dialysis. A number of biologically plausible mechanisms related to hepatitis C virus have been hypothesized to contribute to atherosclerosis. Implementation of effective treatment intervention towards hepatitis C is required to decrease the healthcare burden of hepatitis C and to prevent the progression of chronic renal disease.

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