scholarly journals Clinical value of turbidity-elimination gout soup combined with external application of traditional chinese medicine to improve the pain and the volume of tophi in patients with gout

Author(s):  
Hongbo LI ◽  
Daqing NIE ◽  
Shaoqiong WANG ◽  
Da LI ◽  
Cheng LIU
2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Xin Li ◽  
Qing-qing Xiao ◽  
Kan Ze ◽  
Su Li ◽  
Yi-fei Wang ◽  
...  

Objective. To evaluate the effectiveness of external application of traditional Chinese medicine (EA-TCM) on venous ulcers.Methods. Seven databases were searched until April 2015 for randomized controlled trials (RCTs) of EA-TCM for venous ulcers. Risk of bias was assessed using Cochrane Handbook guidelines. Study outcomes were presented as risk ratios (RRs) for dichotomous data or mean differences (MDs) for continuous data.Results. Sixteen of 193 potentially relevant trials met the inclusion criteria; however, their methodological qualities were low. Comparison of the same intervention strategies revealed significant differences in total effectiveness rates between EA-TCM and conventional therapy groups (RR = 1.22, 95% confidence interval [CI] = 1.16–1.29, andP<0.00001). Compared to conventional therapy, EA-TCM combined with conventional therapy had a superior total effectiveness rate (RR = 1.11, 95% CI = 1.04–1.19, andP=0.003). There were no significant differences in recurrence rates during followup and final pain measurements between the experimental and those in the control groups (RR = 0.86, 95% CI = 0.31–2.39, andP=0.85; MD −0.75, 95% CI = −2.15–0.65, andP=0.29).Conclusion. The evidence that EA-TCM is an effective treatment for venous ulcers is encouraging, but not conclusive due to the low methodological quality of the RCTs. Therefore, more high-quality RCTs with larger sample sizes are required.


2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Yang Yang ◽  
Xin Jin ◽  
Xinyi Jiao ◽  
Jinjing Li ◽  
Liuyi Liang ◽  
...  

Chronic obstructive pulmonary disease (COPD) is a common respiratory disease with high morbidity and mortality. The conventional therapies remain palliative and have various undesired effects. Flavonoids from traditional Chinese medicine (TCM) have been proved to exert protective effects on COPD. This review aims to illuminate the poly-pharmacological properties of flavonoids in treating COPD based on laboratory evidences and clinical data and points out possible molecular mechanisms. Animal/laboratory studies and randomised clinical trials about administration of flavonoids from TCM for treating COPD from January 2010 to October 2020 were identified and collected, with the following terms: chronic obstructive pulmonary disease or chronic respiratory disease or inflammatory lung disease, and flavonoid or nature product or traditional Chinese medicine. Pharmacokinetic studies and external application treatment were excluded. A total of 15 flavonoid compounds were listed. Flavonoids could inhibit inflammation, oxidative stress, and cellular senescence, restore corticosteroid sensitivity, improve pulmonary histology, and boost pulmonary function through regulating multiple targets and signaling pathways, which manifest that flavonoids are a group of promising natural products for COPD. Nevertheless, most studies remain in the research phase of animal testing, and further clinical applications should be carried out.


2015 ◽  
Vol 24 (1) ◽  
pp. 11-17 ◽  
Author(s):  
Yan Xiangyong ◽  
Yan Zhongsheng ◽  
Liu Wenchao ◽  
Ding Hui ◽  
Qiao Shuzhou ◽  
...  

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e23131-e23131
Author(s):  
Peng Lv ◽  
Ya Li ◽  
Zhenzhu Zhang ◽  
Fengqin Shi ◽  
Li Hou

e23131 Background: Comparative study results between the efficacies of traditional Chinese medicine (TCM) therapy with Western medicine therapy in the treatment of cancer pain remain controversial. We use the standardized step treatment as a common control to compare the effectiveness of different Chinese medical methods combined with standardized step therapy for cancer pain using a network meta-analysis. Methods: Randomized controlled trials of the effectiveness of various Chinese medical methods and standardized ladder treatments in PubMed, The Cochrane Library, EmBase, Web of Science, CNKI, VIP, and Wan-Fang databases were searched. Stata14.0 and WinBUGS1.4.3 software were used for statistical analysis. Risk ratio(RR) with their 95% confidence interval were estimated as effect size between treatments. Results: Seventy RCTs were included, a total of 6,936 patients with cancer pain, involving five treatments.The results of network meta-analysis showed that there were significant statistical differences between the four Chinese medical methods combined with standardized step treatment and simple standardized step treatment: Chinese medicine orally combined with standardized step treatment vs simple standardized step treatment: RR = 2.60, 95% CI (2.09, 3.30); Chinese medicine external application combined with standardized ladder treatment vs simple standardized ladder treatment: RR = 2.83, 95% CI (2.31, 3.50); acupuncture physiotherapy combined with standardized ladder treatment vs simple standardized ladder treatment: RR = 3.56, 95% CI (1.92, 7.26); Chinese medicine injection combined with standardized ladder treatment vs simple standardized ladder treatment: RR = 2.22, 95% CI (1.63, 3.05). Conclusions: There are significant statistical differences between different Chinese medical methods combined with standardized step treatment and simple standardized step treatment. For patients with cancer pain, standardized step therapy combined with acupuncture physiotherapy or external application of traditional Chinese medicine can be preferred. Due to the lack of existing research, the conclusions of the study need to be confirmed by high quality RCT.


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