scholarly journals Atomic force microscopy reveals different surface morphologies of functionally-different glial cells

2000 ◽  
Vol 72 (3) ◽  
pp. 433-433
Author(s):  
GILBERTO WEISSMÜLLER ◽  
JOSÉ GARCIA-ABREU ◽  
PAULO MASCARELLO BISCH ◽  
VIVALDO MOURA NETO ◽  
LENY A. CAVALCANTE
2021 ◽  
Vol 18 (4) ◽  
pp. 21-28
Author(s):  
Simona Maria Ţîrcă ◽  
Ion Ţîrcă ◽  
Marius Sorin Ciontea ◽  
Florin Dumitru Mihălţan

Abstract Atopic dermatitis (AD)-the commonest inflammatory skin disease affects up to 25% of children and 2% to 5% of adults. Methods of the diagnostic provide expanded recommendations founded on available evidence. Morphological evaluation remains a principal feature of clinical investigation and the main criteria of diagnosis. Methods. We collected normal and affected skin from a 6-month child patient who was diagnosed through dermatologic examination. Clinical characteristics and the diagnosis of atopic dermatitis were in accordance with Hanifin and Rajka criteria. Morphology and structural integrity were investigated by Atomic Force Microscopy. Results. Optical and topography images indicate that in the case of AD skin lesions the cuticle structure was severely damaged and distorted with the flattening and grading of the plates, which have an irregular appearance. From the surface morphologies of the samples, we demonstrate that the shape of the corneocytes, with granular and elongated appearance, specific to normal skin is transformed by AD into broken and collapsed plates with discontinuous appearance. Conclusions. In the initial diagnosis of AD changes of the skin properties can be an indicator. Hanifin and Rajka criteria together with Atomic Force Microscopy can be a useful and necessary technique diagnosing cases of atopic dermatitis.


1994 ◽  
Vol 33 (Part 1, No. 7A) ◽  
pp. 4075-4079 ◽  
Author(s):  
Young Soo Yoon ◽  
Young-Ku Yoon ◽  
Jeong Yong Lee ◽  
Sang Seop Yom

1993 ◽  
Vol 11 (4) ◽  
pp. 773-775 ◽  
Author(s):  
V. Parpura ◽  
P. G. Haydon ◽  
D. S. Sakaguchi ◽  
E. Henderson

2005 ◽  
Vol 277 (1-4) ◽  
pp. 555-559 ◽  
Author(s):  
Y.L. Geng ◽  
D. Xu ◽  
Y.L. Wang ◽  
W. Du ◽  
H.Y. Liu ◽  
...  

Science ◽  
1992 ◽  
Vol 257 (5078) ◽  
pp. 1944-1946 ◽  
Author(s):  
E Henderson ◽  
P. Haydon ◽  
D. Sakaguchi

1998 ◽  
Vol 37 (Part 1, No. 6B) ◽  
pp. 3849-3854 ◽  
Author(s):  
Yukako Yamane ◽  
Dai Hatakeyama ◽  
Takuro Tojima ◽  
Kazushige Kawabata ◽  
Tatsuo Ushiki ◽  
...  

1996 ◽  
Vol 182 (2) ◽  
pp. 114-120 ◽  
Author(s):  
P. G. HAYDON ◽  
R. LARTIUS ◽  
V. PARPURA ◽  
S. P. MARCHESE-RAGONA

e-Polymers ◽  
2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Caixia Ma ◽  
Zongyi Qin ◽  
Ding Pan

AbstractThe as-formed structure of gel-spun polyacrylonitrile (PAN) fiber from the solvent mixture system has been probed exploiting AFM techniques developed in the membrane industry. The surface structure of PAN membranes, prepared by phase transition under different casting conditions, was investigated by tapping mode atomic force microscopy. The results obtained show that the size and the density of these aggregates are dependent on the casting solution, namely on the type and concentration of the non-solvent. In the present work, tapping mode atomic force microscopy is used to comply with the main objective of differentiating surface morphologies of membranes.


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