scholarly journals Genetic variability of hepatitis A virus strain HAF-203 isolated in Brazil and expression of the VP1 gene in Escherichia coli

2006 ◽  
Vol 101 (7) ◽  
pp. 759-766 ◽  
Author(s):  
Marcia L Baptista ◽  
Messias Silva ◽  
Maria Amélia de Lima ◽  
Clara FT Yoshida ◽  
Ana Maria C Gaspar ◽  
...  
1987 ◽  
Vol 61 (11) ◽  
pp. 3645-3647 ◽  
Author(s):  
R Ostermayr ◽  
K von der Helm ◽  
V Gauss-Müller ◽  
E L Winnacker ◽  
F Deinhardt

Virology ◽  
1994 ◽  
Vol 204 (1) ◽  
pp. 60-68 ◽  
Author(s):  
Judith Graff ◽  
Christa Kasang ◽  
Andrea Normann ◽  
Mechtild Pfisterer-Hunt ◽  
Stephen M. Feinstone ◽  
...  

2003 ◽  
Vol 84 (12) ◽  
pp. 3191-3201 ◽  
Author(s):  
Mauro Costa-Mattioli ◽  
Anna Di Napoli ◽  
Virginie Ferré ◽  
Sylviane Billaudel ◽  
Raul Perez-Bercoff ◽  
...  

Knowledge of the molecular biology of hepatitis A virus (HAV) has increased exponentially since its identification. HAV exploits all known mechanisms of genetic variation to ensure survival, including mutation and genetic recombination. HAV has been characterized by the emergence of different genotypes, three human antigenic variants and only one major serotype. This paper reviews the genetic variability and molecular epidemiology of HAV. Its evolutionary mechanisms are described with particular emphasis on genetic recombination and HAV mutation rate. Genotypic classification methods are also discussed.


1975 ◽  
Vol 148 (2) ◽  
pp. 532-539 ◽  
Author(s):  
P. J. Provost ◽  
B. S. Wolanski ◽  
W. J. Miller ◽  
O. L. Ittensohn ◽  
W. J. McAleer ◽  
...  

2000 ◽  
Vol 88 (2) ◽  
pp. 293-298 ◽  
Author(s):  
L. Croci ◽  
D. De Medici ◽  
C. Scalfaro ◽  
A. Fiore ◽  
M. Divizia ◽  
...  

2003 ◽  
Vol 69 (3) ◽  
pp. 1840-1843 ◽  
Author(s):  
Glòria Sánchez ◽  
Santiago Caballero ◽  
Susana Guix ◽  
Albert Bosch ◽  
Rosa M. Pintó

ABSTRACT The synthesis of 14S pentamers and 70S empty capsids of hepatitis A virus (HAV) has been accomplished by expressing the viral genome for periods of time longer than 4 h in Escherichia coli. HAV pentamers (14S) self-assembled into capsids (70S) in vitro. The antibodies induced by these structures recognized and neutralized HAV.


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