Malformations of cortical development in patients with midline facial defects and ocular hypertelorism

2009 ◽  
pp. 100611121139056
Author(s):  
Silvyo Giffoni ◽  
Fernando Cendes ◽  
Marcelo Valente ◽  
Vera Gil-da-Silva-Lopes
Keyword(s):  
Cortical Development ◽  
Malformations Of Cortical Development ◽  
Facial Defects ◽  
Ocular Hypertelorism

Malformations of Cortical Development in Patients with Midline Facial Defects and Ocular Hypertelorism

2010 ◽  
Vol 47 (4) ◽  
pp. 343-351 ◽  
Author(s):  
Silvyo David Araújo Giffoni ◽  
Fernando Cendes ◽  
Marcelo Valente ◽  
Vera Lucia Gil-Da-Silva-Lopes
Keyword(s):  
Cortical Development ◽  
Malformations Of Cortical Development ◽  
Facial Defects ◽  
Ocular Hypertelorism

Quantitative 1H-MRS reveals metabolic difference between subcategories of malformations of cortical development

2021 ◽  
Author(s):  
Qiaoyue Tan ◽  
Wenyu Liu ◽  
Xinyue Wan ◽  
Weina Wang ◽  
Xiaorui Su ◽  
...  
Keyword(s):  
Cortical Development ◽  
Malformations Of Cortical Development ◽  
1H Mrs ◽  
Metabolic Difference

scholarly journals Malformations of Cortical Development, Cognitive Involvementand Epilepsy: A Single Institution Experience in 19 Young Patients

Children ◽  
2021 ◽  
Vol 8 (8) ◽  
pp. 637
Author(s):  
Valeria Venti ◽  
Maria Chiara Consentino ◽  
Pierluigi Smilari ◽  
Filippo Greco ◽  
Claudia Francesca Oliva ◽  
...  
Keyword(s):  
Clinical Features ◽  
Cortical Development ◽  
Young Patients ◽  
Cortical Dysplasia ◽  
Drug Resistant ◽  
Malformations Of Cortical Development ◽  
Group Iii ◽  
Group I ◽  
Cognitive Involvement ◽  
Group Ii

Background. Malformations of cortical development (MCD) include a wide range of congenital disorders mostly causing severe cognitive dysfunction and epilepsy. Objective: to report on clinical features including cognitive involvement, epileptic seizures with response to antiseizure medications, comorbidities in young patients affected by MCD and followed in a single tertiary hospital. Patients and methods: A retrospective review of the medical records and magnetic resonance images (MRI) of 19 young patients with an age ranging between eight days and fifteen years affected by MCD and admitted to Pediatrics Department University of Catania, Italy from October 2009 and October 2020 were selected. Patients were distinguished in three groups following the Barcovich et al. 2012 classification for MCD: 4 (21%) in Group I; 8 (42%) in Group II; and, and 7 (37%) in Group III. Clinical features and MRI of the patients including cognitive involvement, epilepsy type and response to drugs treatment were analyzed. Results: In Group I, two patients showed cortical dysplasia and two dysembryoplastic neuroepithelial tumors plus focal cortical dysplasia; developmental delay/intellectual disability (DD/ID) was severe in one, moderate in one and absent in two; the type of seizures was in all the cases focal to bilateral tonic-clonic (FBTCs), and drug resistant was found in one case. In Group II, three patients showed neuronal hetero-topias and five had pachygyria-lissencephaly: DD/ID was severe in four, moderate in two, and absent in two; the type of seizure was focal (FS) in five, focal to bilateral tonic-clonic (FBTCs) in two, infantile spasms (IS) in one, and drug resistant was found in three. In Group III, six showed polymicrogyria and one schizencephaly: DD/ID was found severe in five, moderate in two, and the type of seizure was focal (FS) in five, FBTCS in two, and drug resistance was found in three.

scholarly journals Teaching NeuroImages: Brain MRI and FDG-PET in malformations of cortical development and hippocampal hypoplasia

Neurology ◽  
2011 ◽  
Vol 77 (8) ◽  
pp. e47-e47 ◽  
Author(s):  
D. Renard ◽  
G. Castelnovo ◽  
D. Daubin ◽  
L. Collombier ◽  
C. Briere ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Brain Mri ◽  
Cortical Development ◽  
Malformations Of Cortical Development

Heterogeneous epileptogenicity and cortical function within malformations of cortical development: A case report

2006 ◽  
Vol 251 (1-2) ◽  
pp. 129-133
Author(s):  
Masako Kinoshita ◽  
Akio Ikeda ◽  
Junya Taki ◽  
Keiko Usui ◽  
Riki Matsumoto ◽  
...  
Keyword(s):  
Case Report ◽  
Cortical Development ◽  
Malformations Of Cortical Development ◽  
Cortical Function

scholarly journals Malformations of cortical development: current concepts and advanced neuroimaging review

2011 ◽  
Vol 69 (1) ◽  
pp. 130-138 ◽  
Author(s):  
Celi Santos Andrade ◽  
Claudia da Costa Leite
Keyword(s):  
Imaging Techniques ◽  
Cortical Development ◽  
Motor Dysfunction ◽  
Malformations Of Cortical Development ◽  
Neurodevelopmental Delay ◽  
Complex Process ◽  
Magnetic Resonance Imaging Mri ◽  
Specific Disorders ◽  
Patients With Epilepsy ◽  
Work Up

Malformations of cortical development (MCD) result from disruptions in the complex process of the human brain cortex formation and are highly associated to severe epilepsy, neurodevelopmental delay and motor dysfunction. Nowadays, magnetic resonance imaging (MRI) is the cornerstone of the work-up of patients with epilepsy and modern advanced imaging techniques have improved not only our ability to detect and characterize cortical malformations, but also in identifying associated functional abnormalities that are far beyond the structural visualized lesions. Herein, we address the most currently used classifications of MCD and make a concise review of the embryological process of cortical development. Our main goal is to summarize recent advances and new trends in diagnostic imaging techniques concerning MCD. Thereafter, follows a brief discussion of specific disorders and their radiological features.

Genetic malformations of cortical development

2006 ◽  
Vol 173 (2) ◽  
pp. 322-333 ◽  
Author(s):  
Renzo Guerrini ◽  
Carla Marini
Keyword(s):  
Cortical Development ◽  
Malformations Of Cortical Development
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