Comparison of Craniofacial and Dentoalveolar Morphologies of Three Japanese Monozygotic Twin Pairs with Cleft Lip and/or Palate Discordancy

1998 ◽  
Vol 35 (2) ◽  
pp. 173-180 ◽  
Author(s):  
Keiji Moriyama ◽  
Nobuyoshi Motohashi ◽  
Atsushi Kitamura ◽  
Takayuki Kuroda
Keyword(s):  
Growth And Development ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Monozygotic Twins ◽  
Monozygotic Twin ◽  
Surgical Closure ◽  
Bilateral Cleft Lip ◽  
Morphological Differences ◽  
Cast Analysis ◽  
Dental Cast

Objective In this study, we analyzed the craniofacial and dentoalveolar morphologies of three pairs of monozygotic twins discordant for cleft lip and/or palate (CL/P) in order to evaluate the effects of environmental factors on growth and development. Design Craniofacial and dentoalveolar morphologies revealed by analyses of cephalograms and dental casts were compared for each pair of twins discordant for CUP. Subjects In case 1, the subjects were 10-year-old male twins, one of whom had a repaired unilateral cleft lip and alveolus and one of whom had an unrepaired unilateral cleft lip. In case 2, the subjects were 13-year-old female twins, one of whom had a repaired bilateral cleft lip and palate and one of whom had an unrepaired unilateral cleft lip. In case 3, the subjects were 9-year-old female twins, one of whom had a repaired unilateral cleft lip and palate and one of whom had no cleft. Results Cephalometric analysis disclosed distinguished intrapair differences in the maxillary and mandibular morphologies in cases 2 and 3. However, the tooth axes of the incisors in operated subjects were consistently influenced in all three cases. Dental cast analysis indicated that the shapes and sizes of the alveolar and dental arches in the operated subjects were affected in case 2 and, more severely, in case 3, while they looked fairly similar in case 1. Conclusions Cephalometric and dental cast analyses demonstrated characteristic intrapair differences between the twins discordant for CL/P according to each cleft type. These morphological differences indicate that surgical closure of clefts may have considerable effects on craniofacial and dentoalveolar growth and development in CL/P patients.

Craniofacial Morphology in Children with Complete Bilateral Cleft Lip and Palate: Does Infantile Size of the Premaxilla Predetermine Outcome?

2004 ◽  
Vol 41 (4) ◽  
pp. 410-415 ◽  
Author(s):  
Yu-Fang Liao ◽  
Chiung-Shing Huang ◽  
Ya-Yu Tsai ◽  
M. Samuel Noordhoff
Keyword(s):  
Retrospective Study ◽  
Outcome Measures ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Craniofacial Morphology ◽  
University Hospital ◽  
Cephalometric Analysis ◽  
Bilateral Cleft Lip ◽  
Dental Cast ◽  
Craniofacial Characteristics

Objective To evaluate the possible association between the size of the premaxilla in infants and craniofacial morphology in children with complete bilateral cleft lip and palate (CBCLP) and identify the characteristics of craniofacial morphology in children with CBCLP with median facial dysplasia (MFD). Design Retrospective study. Setting A university hospital craniofacial center. Subjects Thirty-four patients with nonsyndromic CBCLP, 24 boys and 10 girls, had large premaxilla (LP group). Thirty-six patients with nonsyndromic CBCLP, 16 boys and 20 girls, had small premaxilla (SP group). Thirteen CBCLP patients with MFD, five boys and eight girls (MFD group). Main Outcome Measures Infant maxillary dental cast at the age of 1 year was used to measure the size of the premaxilla. Cephalometric analysis was used to determine craniofacial morphology in children at the age of 5 years. Results The size of the premaxilla in infants with CBCLP varied greatly. The LP group tended to have a longer maxilla and a more protruded maxilla, producing a better interjaw relation. The opposite phenomena were observed in the MFD group; the SP group yielded results between those of the LP and the MFD groups. Conclusion The size of the premaxilla in infants with CBCLP can be used to predetermine subsequent craniofacial morphology at the age of 5 years. Children with nonsyndromic CBCLP had craniofacial characteristics that differed significantly from those of children with CBCLP with median facial dysplasia.

Blepharo-Cheilo-Dontic (BCD) Syndrome: Case Report

2006 ◽  
Vol 43 (2) ◽  
pp. 237-243 ◽  
Author(s):  
Akihiko Iida ◽  
Shota Narai ◽  
Ritsuo Takagi ◽  
Kazuhiro Ono ◽  
Nobuyuki Ikeda
Keyword(s):  
Case Report ◽  
Active Treatment ◽  
Growth And Development ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Scalp Hair ◽  
Treatment Plan ◽  
Fatal Complication ◽  
Left Hand ◽  
Bilateral Cleft Lip

Objective To report a case of blepharo-cheilo-dontic (BCD) syndrome, to compare with the previous cases, and to discuss the possible treatment. Patient The patient was a 14-day-old boy born uneventfully on August 7, 2002. His scalp hair was sparse and curly. A tumor on the top of his head, which was thought to be a dermoid cyst, and a nevus on the back of his left hand were observed. All typical symptoms of blepharo-cheilo-dontic syndrome, such as euryblepharon with ectropion of the lower eyelids, distichiasis, bilateral cleft lip and palate, severe oligodontia, and conical teeth, were observed. Because there was no fatal complication, and growth and development were about normal, it was recommended that a long and active treatment plan be considered for this patient.

Use of Bauru Yardstick in Patients With Complete Bilateral Cleft Lip and Palate at an Indian Center

2017 ◽  
Vol 55 (4) ◽  
pp. 602-606
Author(s):  
Puneet Batra ◽  
Gopala Krishna Annavarapv ◽  
Ashish Chopra ◽  
Amit Srivastava ◽  
Partha Sadhu ◽  
...  
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Weighted Kappa ◽  
Dental Arch ◽  
Age Group ◽  
Bilateral Cleft Lip ◽  
Examiner Agreement ◽  
Dental Cast ◽  
Dental Arch Relationship ◽  
Very High

Objective: To evaluate dental arch relationship in treated bilateral cleft lip and palate (BCLP) cases at an Indian cleft center using the Bauru yardstick. Patients and methods: Digital photographs of the dental cast of 50 consecutively treated patients (28 males and 22 females) with nonsyndromic BCLP at an Indian cleft center were rated by 2 examiners as per the Bauru yardstick for the 12-year-old age group. The average age group was 12 ± 0.62 years. All cases were treated with same surgical protocol. Results: The inter-examiner agreement between the 3 examiners was found to be very high, with weighted kappa values ranging from 0.894 to 0.951. The intraexaminer agreement between the 2 examinations for all the examiners was also found to be very high, with weighted kappa values ranging from 0.894 to 0.931. Seventy-eight percent of patients were rated with a Bauru yardstick score of 1+2. In addition, 10% of patients were rated with a score of 3, 8% as 4, and 4% as 5. The overall Bauru yardstick score for the center was 2.36. Conclusion: The protocol followed for the repair of BCLP cases by the center was found to be a good regimen in regard to the Bauru yardstick score.

scholarly journals Therapeutic experience with bilateral cleft lip and palate and unilateral cleft lip and alveolus in a pair of monozygotic twin sisters

2013 ◽  
Vol 59 (8) ◽  
pp. 517-521
Author(s):  
Keiichi ARAKAKI ◽  
Toshimoto TENGAN ◽  
Takahiro GOTO ◽  
Shigeki SAWADA ◽  
Joji NAKAMA ◽  
...  
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Monozygotic Twin ◽  
Therapeutic Experience ◽  
Bilateral Cleft Lip

scholarly journals Discussion on Craniomaxillofacial Growth and Development in a Patient Surgically Treated for Bilateral Cleft Lip and Palate

2010 ◽  
Vol 30 (2) ◽  
pp. 142-150
Author(s):  
Takako OHSHIMA ◽  
Yuko TOI ◽  
Haruhisa NAKANO ◽  
Hitomi KURABAYASHI ◽  
Koutaro MAKI ◽  
...  
Keyword(s):  
Growth And Development ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Bilateral Cleft Lip

Presurgical Orthopedic Premaxillary Alignment in Cleft Lip and Palate Reconstruction

1994 ◽  
Vol 31 (6) ◽  
pp. 494-498 ◽  
Author(s):  
Frank A. Papay ◽  
Louis Morales ◽  
David S. Motoki ◽  
Duane K. Yamashiro
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Difficult Problem ◽  
Surgical Closure ◽  
The Past ◽  
Submucosal Tunnel ◽  
Nasal Floor ◽  
Bilateral Cleft Lip ◽  
Palate Repair ◽  
A New Technique

Premaxillary malposition is a difficult problem in cleft lip and palate repair. Orthopedic palatal devices are excellent in positioning the premaxilla, though they are somewhat cumbersome and require complex techniques in adjusting precisely the position of the premaxilla prior to repair. A new technique has been developed for premaxillary repositioning in conjunction with palatal shelf expansion and obturation. The procedure implements microplate fixation anterior to the premaxillary segment and linked to a palatal splint by adjustable elastics. The microplate is Inserted through a nasal floor incision and secured by a tight submucosal tunnel through minimal dissection between the prolabium and premaxllla. The last hole of each mlcroplate protrudes through the mucosa and is attached to a pin-retained palatal splint by an elastic chain. Differential tension is applied to the chains to allow gradual repositioning of the protruding maxilla while the splint expands and maintains positioning of the lateral palatal segments. These elastic retractors can be adjusted by staff in the outpatient office. During the past 2 years, this technique has been used successfully in 21 consecutive patients with unilateral or bilateral cleft lip and palate. Its technical ease and design allows simple adjustments to control premaxillary positioning and growth before definitive surgical closure.

Growth Study Including Stereophotogrammetry of a Pair of Monozygotic Twins, One Having a Cleft Lip and Palate

1987 ◽  
Vol 14 (2) ◽  
pp. 73-84 ◽  
Author(s):  
P. Burke ◽  
C. Hughes
Keyword(s):  
Soft Tissue ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Monozygotic Twins ◽  
Monozygotic Twin ◽  
Tissue Growth ◽  
Facial Growth ◽  
Growth Study ◽  
The Face ◽  
Growth Changes

This report is a serial growth study of a pair of monozygotic twin boys, one of whom suffered from a bilateral cleft of the lip and a unilateral cleft of the palate. Annual records for height and weight were registered from seven years eight months to 18 years 0 months. Soft tissue facial growth was also measured annually using short base stereophotogrammetry (Burke, 1967). Growth and development of the dentition was recorded as orthodontic study models at less frequent intervals. Measurements derived from the facial maps allowed not only measurement of soft tissue growth changes in the face, but also of surgical change to both lips related to an Abbe flap procedure carried out for the cleft twin. All changes are compared with those occurring in his monozygotic twin.

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