scholarly journals Harnessing Cyc to Answer Clinical Researchers' Ad Hoc Queries

AI Magazine ◽  
2010 ◽  
Vol 31 (3) ◽  
pp. 13 ◽  
Author(s):  
Douglas Lenat ◽  
Michael Witbrock ◽  
David Baxter ◽  
Eugene Blackstone ◽  
Chris Deaton ◽  
...  
Keyword(s):  
Domain Knowledge ◽  
Ad Hoc ◽  
Cleveland Clinic ◽  
Cleveland Clinic Foundation ◽  
Text Search ◽  
False Negatives ◽  
Higher Order Logic ◽  
Clinic Foundation ◽  
Standard Text ◽  
Text Searching

By extending Cyc’s ontology and KB approximately 2%, Cycorp and Cleveland Clinic Foundation (CCF) have built a system to answer clinical researchers’ ad hoc queries. The query may be long and complex, hence only partially understood at first, parsed into a set of CycL (higher-order logic) fragments with open variables. But, surprisingly often, after applying various constraints (medical domain knowledge, common sense, discourse pragmatics, syntax), there is only one single way to fit those fragments together, one semantically meaningful formal query P. The system, SRA (for Semantic Research Assistant), dispatches a series of database calls and then combines, logically and arithmetically, their results into answers to P. Seeing the first few answers stream back, the user may realize that they need to abort, modify, and re-ask their query. Even before they push ASK, just knowing approximately how many answers would be returned can spark such editing. Besides real-time ad hoc query-answering, queries can be bundled and persist over time. One bundle of 275 queries is rerun quarterly by CCF to produce the procedures and outcomes data it needs to report to STS (Society of Thoracic Surgeons, an external hospital accreditation and ranking body); another bundle covers ACC (American College of Cardiology) reporting. Until full articulation/answering of precise, analytical queries becomes as straight-forward and ubiquitous as text search, even partial understanding of a query empowers semantic search over semi-structured data (ontology-tagged text), avoiding many of the false positives and false negatives that standard text searching suffers from.

Medical PhysicsMedical Physics. Editor-in-Chief, GlasserOtto Glasser, Ph.D., Head of Department of Biophysics, Cleveland Clinic Foundation; Professor of Biophysics, Frank E. Bunts Educational Institute; Consulting Biophysicist, University Hospitals of Cleveland, Cleveland, Ohio. Associate Editors:Anatomy:HoerrNormand L., M.D., Ph.D.;Bacteriology:RahmOtto, Ph.D.;Biometrics:WinsorCharles P., Ph.D.;Biophysics:GlasserOtto, Ph.D.;Dermatology:BinkleyGeorge W., M.D.;Hematology:PonderEric, M.D., D.Sc.;Medicine:HadenRussell L., M.D.;Neurology:GardnerW. James, M.D.;Nuclear Physics:EvansRobley D., Ph.D.:Ophthalmology:RuedemannAlbert D., M.D.;Optics:RaytonW. B., D.Sc.;Orthopedics:DicksonJames A., M.D.;Otolaryngology:MoorePaul M.Jr., M.D.;Pathology:GoldblattHarry, M.D., C.M.;Pediatrics:WetzelNorman C., M.D.;Photography:MassopustLeo C.;Physical Chemistry:WhitacreFrancis M., Ph.D.;Physical Therapy:ZeiterWalter J., M.D.;Physics(Instruments and Methods): AlbrightJohn G., Ph.D.;Physiology:GreenHarold D., M.D.;Radiology:HauserHarry, M.D.;Surgery:MautzFrederick R., M.D.;Urology:HigginsCharles C., M.D. A volume of 1744 pages, with numerous illustrations. Published by The Year Book Publishers, Inc., Chicago. Price $18.

Radiology ◽  
1944 ◽  
Vol 42 (6) ◽  
pp. 600-600
Keyword(s):  
Cleveland Clinic ◽  
Cleveland Clinic Foundation ◽  
University Hospitals ◽  
Clinic Foundation ◽  
Educational Institute ◽  
Head Of Department ◽  
Book Publishers ◽  
Cleveland Ohio

Tracheoesophageal Puncture for Alaryngeal Voice Restoration

1981 ◽  
Vol 90 (5) ◽  
pp. 492-494 ◽  
Author(s):  
Benjamin G. Wood ◽  
Melinda G. Rusnov ◽  
Harvey M. Tucker ◽  
Howard L. Levine
Keyword(s):  
Surgical Technique ◽  
Cleveland Clinic ◽  
Cleveland Clinic Foundation ◽  
Factors Affecting ◽  
Voice Restoration ◽  
Clinic Foundation ◽  
Communicative Disorders ◽  
Tracheoesophageal Puncture

Thirty-two tracheoesophageal punctures (TEP) were performed on 30 patients by The Cleveland Clinic Foundation Department of Otolaryngology and Communicative Disorders. In all cases, the Blom-Singer duckbill prosthesis was utilized for alaryngeal voice restoration. Ninety-three percent of patients were able to produce significantly better voice following TEP when compared to their preoperative mode of communication. The preoperative orientation/evaluation format, surgical technique, success-failure ratios, and possible factors affecting successful TEP voice restoration are examined.

scholarly journals Cleveland Clinic Foundation Internal Medicine Residency Program

2020 ◽  
Vol 38 (2) ◽  
pp. 190-193
Author(s):  
Christine Zayouna ◽  
Jessica El-Asmar ◽  
Ahmad Abu-Haniyeh ◽  
Shailee Shah ◽  
Karam Al-Issa ◽  
...  
Keyword(s):  
Internal Medicine ◽  
Residency Program ◽  
Cleveland Clinic ◽  
Cleveland Clinic Foundation ◽  
Internal Medicine Residency ◽  
Internal Medicine Residency Program ◽  
Clinic Foundation

MEDICAL TOURISM AND DIABETES CARE: EXPERIENCE FROM A TERTIARY REFERRAL CENTER

2020 ◽  
Vol 26 (10) ◽  
pp. 1125-1130
Author(s):  
Khawla F. Ali ◽  
Alexandra Mikhael ◽  
Christine Zayouna ◽  
Omar A. Barakat ◽  
James Bena ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
United States ◽  
Hemoglobin A1c ◽  
Medical Tourism ◽  
Cleveland Clinic ◽  
The United States ◽  
Cleveland Clinic Foundation ◽  
Clinic Foundation ◽  
Group 2 ◽  
Group 1

Objective: Medical tourism, a form of patient mobility across international borders to seek medical services, has gained significant momentum. We aimed to assess the outcomes of medical tourism consultations on chronic diseases, more specifically diabetes mellitus, amongst a cohort of international patients, originating from different healthcare systems, and referred to the United States for medical care. Methods: We identified international adults with established diabetes mellitus, referred globally from 6 countries to the United States between 2010 and 2016 for medical care, and were seen at the Cleveland Clinic Foundation (CCF). Group 1 included adults seen by an endocrinology provider during their CCF medical stay, whilst group 2 included those not seen by an endocrinology provider. To assess the impact of our consultations, changes in hemoglobin A1c (HbA1c) were assessed between visit(s). Results: Our study included 1,108 subjects (771 in group 1, 337 in group 2), with a mean age (± SD) of 61.3 ± 12.7 years, 62% male, and a median medical stay of 136 days (interquartile range: 57, 660). Compared to group 2, group 1 had a higher baseline mean HbA1c (8.0 ± 1.8% [63.9 mmol/mol] vs. 7.1 ± 1.4% [54.1 mmol/mol]; P<.001). After 1 visit with endocrinology, there was a significant decrease in mean HbA1c from 8.44 ± 1.98% (68.3 mmol/mol) to 7.51 ± 1.57% (58.5 mmol/mol) ( P<.001). Greatest reductions in mean HbA1c were −1.47% (95% CI: −2.21, −0.74) and −1.27% (95% CI: −1.89, −0.66) after 3 and 4 visits, respectively ( P<.001). Conclusion: Short-term diabetes mellitus consultations, in the context of medical tourism, are effective. Abbreviations: CCF = Cleveland Clinic Foundation; GCC = Gulf Cooperation Council; HbA1c = hemoglobin A1c; IQR = interquartile range; U.S. = United States

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