Estimation of Dose–Response Models for Discrete and Continuous Data in Weed Science

2012 ◽  
Vol 26 (3) ◽  
pp. 587-601 ◽  
Author(s):  
William J. Price ◽  
Bahman Shafii ◽  
Steven S. Seefeldt

Dose–response analysis is widely used in biological sciences and has application to a variety of risk assessment, bioassay, and calibration problems. In weed science, dose–response methodologies have typically relied on least squares estimation under the assumptions of normal, homoscedastic, and independent errors. Advances in computational abilities and available software, however, have given researchers more flexibility and choices for data analysis when these assumptions are not appropriate. This article will explore these techniques and demonstrate their use to provide researchers with an up-to-date set of tools necessary for analysis of dose–response problems. Demonstrations of the techniques are provided using a variety of data examples from weed science.

2001 ◽  
Vol 7 (5) ◽  
pp. 1091-1120 ◽  
Author(s):  
Robert S. DeWoskin ◽  
Stan Barone ◽  
Harvey J. Clewell ◽  
R. Woodrow Setzer

1995 ◽  
Vol 9 (2) ◽  
pp. 218-227 ◽  
Author(s):  
Steven S. Seefeldt ◽  
Jens Erik Jensen ◽  
E. Patrick Fuerst

Dose-response studies are an important tool in weed science. The use of such studies has become especially prevalent following the widespread development of herbicide resistant weeds. In the past, analyses of dose-response studies have utilized various types of transformations and equations which can be validated with several statistical techniques. Most dose-response analysis methods 1) do not accurately describe data at the extremes of doses and 2) do not provide a proper statistical test for the difference(s) between two or more dose-response curves. Consequently, results of dose-response studies are analyzed and reported in a great variety of ways, and comparison of results among various researchers is not possible. The objective of this paper is to review the principles involved in dose-response research and explain the log-logistic analysis of herbicide dose-response relationships. In this paper the log-logistic model is illustrated using a nonlinear computer analysis of experimental data. The log-logistic model is an appropriate method for analyzing most dose-response studies. This model has been used widely and successfully in weed science for many years in Europe. The log-logistic model possesses several clear advantages over other analysis methods and the authors suggest that it should be widely adopted as a standard herbicide dose-response analysis method.


2019 ◽  
Vol 246 ◽  
pp. 566-570 ◽  
Author(s):  
Evgenios Agathokleous ◽  
Alessandro Anav ◽  
Valda Araminiene ◽  
Alessandra De Marco ◽  
Marisa Domingos ◽  
...  

2015 ◽  
Vol 81 ◽  
pp. 137-140 ◽  
Author(s):  
Edward J. Calabrese ◽  
Dima Yazji Shamoun ◽  
Jaap C. Hanekamp

Sign in / Sign up

Export Citation Format

Share Document