Modulatory Effect of Crude Aqueous Extract of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Higher Basidiomycetes), on Hematological and Antioxidant Indices in Plasmodium berghei-infected Mice

2014 ◽  
Vol 16 (5) ◽  
pp. 499-506 ◽  
Author(s):  
Olarewaju M. Oluba ◽  
Kayode E. Adebisi ◽  
George O. Eidangbe ◽  
Adewale A. Odutuga ◽  
E. Chukwu Onyeneke
Keyword(s):  
Aqueous Extract ◽  
Plasmodium Berghei ◽  
Ganoderma Lucidum ◽  
Medicinal Mushroom ◽  
Crude Aqueous Extract

scholarly journals Modulation of Lipoprotein Cholesterol Levels in Plasmodium berghei Malarial Infection by Crude Aqueous Extract of Ganoderma lucidum

Cholesterol ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Olarewaju M. Oluba ◽  
Augustine O. Olusola ◽  
George O. Eidangbe ◽  
Leye J. Babatola ◽  
E. Chukwu Onyeneke
Keyword(s):  
Normal Control ◽  
Aqueous Extract ◽  
Plasmodium Berghei ◽  
Ganoderma Lucidum ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Low Density ◽  
Malarial Infection ◽  
Dose Dependent

In this study, attempt is made to establish changes in serum and liver lipoprotein cholesterols accompanying Plasmodium berghei malarial infection in mice treated with aqueous extract of Ganoderma lucidum at 100, 250, and 500 mg/kg body weight in comparison with 15 mg/kg chloroquine (CQ). Significant increases in all the lipoprotein fractions were observed in infected untreated mice compared with normal control mice. Treatment with 100 and 250 mg/kg G. lucidum extract produced significant reduction in serum total cholesterol (TC) and low-density cholesterol (LDL-C) contents compared with 500 mg/kg G. lucidum and CQ. Treatment with CQ, however, produced significant reduction in hepatic TC and LDL-C compared with the extract. A dose-dependent significant increase in serum high-density lipoprotein cholesterol (HDL-C) was observed in the G. lucidum treated mice compared with normal control but significantly lower compared with CQ-treated mice. Liver HDL-C level was significantly higher in CQ-treated mice compared with normal control and significantly lower compared with G. lucidum-treated and infected untreated mice. A dose-dependent effect of the extract was observed in both serum and liver very-low density lipoprotein cholesterol (VLDL-C). The implication of these results is discussed with respect to the parasite survival and proliferation in the serum and liver.

Wound Healing Activity of an Aqueous Extract of the Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Higher Basidiomycetes)

2014 ◽  
Vol 16 (4) ◽  
pp. 345-354 ◽  
Author(s):  
Asheesh Gupta ◽  
Vandana Kirar ◽  
Gaurav Kr. Keshri ◽  
Shefali Gola ◽  
Anju Yadav ◽  
...  
Keyword(s):  
Wound Healing ◽  
Aqueous Extract ◽  
Ganoderma Lucidum ◽  
Medicinal Mushroom ◽  
Wound Healing Activity
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