Scale models give engineers an excellent understanding of the aerodynamic behavior behind their design; nevertheless, scale models are time consuming and expensive. Therefore computer simulations such as Computational Fluid Dynamics (CFD) are an excellent alternative to scale models. One must ask the question, how close are the CFD results to the actual fluid behavior of the scale model? In order to answer this question the engineering team investigated the performance of a large industrial Gas Turbine (GT) exhaust diffuser scale model with performance predicted by commercially available CFD software. The experimental results were obtained from a 1:12 scale model of a GT exhaust diffuser with a fixed row of blades to simulate the swirl generated by the last row of turbine blades five blade configurations. This work is to validate the effect of the turbulent inlet conditions on an axial diffuser, both on the experimental front and on the numerical analysis approach. The object of this work is to bring forward a better understanding of velocity and static pressure profiles along the gas turbine diffusers and to provide an accurate experimental data set to validate the CFD prediction. For the CFD aspect, ANSYS CFX software was chosen as the solver. Two different types of mesh (hexagonal and tetrahedral) will be compared to the experimental results. It is understood that hexagonal (HEX) meshes are more time consuming and more computationally demanding, they are less prone to mesh sensitivity and have the tendancy to converge at a faster rate than the tetrahedral (TET) mesh. It was found that the HEX mesh was able to generate more consistent results and had less error than TET mesh.