scholarly journals Comparative analysis of the IFNG, IL17A, and IL22-regulated transcriptomes in reconstituted human epidermis (RHE), an in-vitro model of full-thickness skin

SPP Datasets ◽  
2020 ◽  
Author(s):  
M Suárez-Fariñas
Keyword(s):  
Comparative Analysis ◽  
In Vitro Model ◽  
Human Epidermis ◽  
Full Thickness ◽  
Full Thickness Skin ◽  
Thickness Skin ◽  
Vitro Model

Initial results with EPI-201, a developing in vitro model of human epidermis

1998 ◽  
Vol 16 ◽  
pp. S86
Author(s):  
Mitchell Klausner ◽  
Patricia Neal ◽  
Joseph Kubilus
Keyword(s):  
In Vitro Model ◽  
Human Epidermis ◽  
Vitro Model ◽  
Initial Results

Ultrastructural and Immunohistochemical Characterization of an in Vitro Model of Human Epidermis: Its Potential for Sulfur Mustard Study

1997 ◽  
Vol 16 (3) ◽  
pp. 135-144 ◽  
Author(s):  
J. P. Petrali ◽  
P. T. Lopolito ◽  
S. B. Oglesby-Megee ◽  
T. A. Hamilton ◽  
L. S. Rhoads
Keyword(s):  
In Vitro Model ◽  
Sulfur Mustard ◽  
Human Epidermis ◽  
Vitro Model

scholarly journals The Co-Culture of ASCs and EPCs Promotes Wound Healing by Promoting Angiogenesis in Full Thickness Skin Defects

2020 ◽  
Author(s):  
Shuang Lin ◽  
Xiaoning He ◽  
Yuanjia He
Keyword(s):  
Culture System ◽  
Large Scale ◽  
Donor Site ◽  
Skin Tissue ◽  
Skin Defect ◽  
Full Thickness ◽  
Skin Defects ◽  
Full Thickness Skin ◽  
Thickness Skin

Abstract Background The repair of large-scale full-thickness skin defects represents a challenging obstacle in skin tissue engineering. To address the most important problem in skin defect repair, namely insufficient blood supply, this study aimed to find a method that could promote the formation of vascularized skin tissue. Method The phenotypes of ASCs and EPCs were identified respectively, and ASCs/EPCs were co-cultured in vitro to detect the expression of dermal and angiogenic genes. Furthermore, the co-culture system combined with dermal extracellular matrix hydrogel was used to repair the full-scale skin defects in rats.Result The co-culture of ASCs/EPCs could increase skin and angiogenesis-related gene expression in vitro. The results of in vivo animal experiments demonstrated that the ASCs/EPCs group could significantly accelerate the repair of skin defects by promoting the regeneration of vascularized skin.Conclusion It is feasible to replace traditional single seed cells with ASC/EPC co-culture system for vascularized skin regeneration. This system could ultimately enable clinicians to better repair the full-thickness skin defects and avoid donor site morbidity.

Skin corrosion test: a comparison between reconstructed human epidermis and full thickness skin models

2018 ◽  
Vol 125 ◽  
pp. 51-57 ◽  
Author(s):  
Carolina Motter Catarino ◽  
Tatiana do Nascimento Pedrosa ◽  
Paula Comune Pennacchi ◽  
Silvia Romano de Assis ◽  
Fabrícia Gimenes ◽  
...  
Keyword(s):  
Corrosion Test ◽  
Human Epidermis ◽  
Full Thickness ◽  
Reconstructed Human Epidermis ◽  
Full Thickness Skin ◽  
Thickness Skin

scholarly journals Development of a Full-Thickness Human Skin Equivalent In Vitro Model Derived from TERT-Immortalized Keratinocytes and Fibroblasts

2015 ◽  
Vol 21 (17-18) ◽  
pp. 2448-2459 ◽  
Author(s):  
Christianne M.A. Reijnders ◽  
Amanda van Lier ◽  
Sanne Roffel ◽  
Duco Kramer ◽  
Rik J. Scheper ◽  
...  
Keyword(s):  
Human Skin ◽  
In Vitro Model ◽  
Skin Equivalent ◽  
Full Thickness ◽  
Vitro Model ◽  
Human Skin Equivalent
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