OBSERVATIONS ON THE HUMAN PHARYNGEAL HYPOPHYSIS

1956 ◽  
Vol 14 (1) ◽  
pp. 66-77 ◽  
Author(s):  
J. D. BOYD
Keyword(s):  
Structural Features ◽  
Human Embryos ◽  
Nerve Fibres ◽  
Rathke’S Pouch ◽  
Rathke's Pouch

SUMMARY A derivative of the pharyngeal extremity of Rathke's pouch, with structural features closely resembling those of the adenohypophysis, was found in fifty-three human embryos and foetuses. This pharyngeal hypophysis grows during prenatal life and usually possesses a rich vascularization. In silver impregnated material nerve fibres derived from branches of the spheno-palatine ganglion could be followed into the pharyngeal hypophysis. The recorded findings and a survey of the literature suggest that the pharyngeal hypophysis is constantly present in man, and that its cells can differentiate, as do those of the adenohypophysis.

Anatomical observations of the development of the pituitary capsule

1980 ◽  
Vol 52 (5) ◽  
pp. 667-670 ◽  
Author(s):  
Je G. Chi ◽  
Myung Ho Lee
Keyword(s):  
Dura Mater ◽  
Mesenchymal Cell ◽  
Human Embryos ◽  
Arachnoid Membrane ◽  
Content Type ◽  
Rathke’S Pouch ◽  
Rathke's Pouch ◽  
Pituitary Glands ◽  
Early Embryonic Stage ◽  
Human Embryos And Fetuses

✓ A morphological study on the development of the pituitary capsule is reported, based on serial or step-sections of 56 pituitary glands from human embryos and fetuses ranging in gestational age from 4 to 40 weeks. Formation of the pituitary capsule is preceded at a very early embryonic stage by mesenchymal cell proliferation around Rathke's pouch when it forms the primitive adenohypophysis. The proportionally large adenohypophysis wraps around the neurohypophysis as it grows down from the diencephalon. Therefore, the fibrous capsule around the adenohypophysis represents the whole hypophysis as a membrane distinct from the dura mater or pia arachnoid membrane. The pituitary capsule appears not be to a derivative of either the dura mater or the pia arachnoid; instead it is a separate covering of the developing Rathke's pouch.

Accumulation of secretory granules in pituitary clonal cells derived from the epithelium of Rathke's pouch

1978 ◽  
Vol 186 (1) ◽  
Author(s):  
Masataka Shiino ◽  
Hiroshi Ishikawa ◽  
EdwardG. Rennels
Keyword(s):  
Secretory Granules ◽  
Rathke’S Pouch ◽  
Rathke's Pouch

Enhancement of the Canonical Wnt Pathway in Rathke's Pouch Results in Pituitary Tumours Reminiscent of Human Adamantinomatous Craniopharyngioma.

2010 ◽  
pp. OR38-3-OR38-3
Author(s):  
Carles Gaston-Massuet ◽  
Cynthia L Andoniadou ◽  
Massimo Signore ◽  
Sajutha Jayakody ◽  
Nicoletta Charolidi ◽  
...  
Keyword(s):  
Wnt Pathway ◽  
Pituitary Tumours ◽  
Rathke’S Pouch ◽  
Rathke's Pouch ◽  
Canonical Wnt Pathway ◽  
Adamantinomatous Craniopharyngioma ◽  
Canonical Wnt

Rathke's pouch morphogenesis in the chick embryo

1979 ◽  
Vol 207 (3) ◽  
pp. 351-366 ◽  
Author(s):  
Antone G. Jacobson ◽  
David M. Miyamoto ◽  
S.-H. Mai
Keyword(s):  
Chick Embryo ◽  
Rathke’S Pouch ◽  
Rathke's Pouch

Sellar enlargement with hyperprolactinemia and a Rathke's pouch cyst

JAMA ◽  
1978 ◽  
Vol 240 (5) ◽  
pp. 471-473 ◽  
Author(s):  
K. M. Trokoudes
Keyword(s):  
Rathke’S Pouch ◽  
Rathke's Pouch

scholarly journals Retinoic acid is required for specification of the ventral eye field and for Rathke's pouch in the avian embryo

2007 ◽  
Vol 51 (3) ◽  
pp. 191-200 ◽  
Author(s):  
Malcolm Maden ◽  
Aida Blentic ◽  
Susan Reijntjes ◽  
Sophie Seguin ◽  
Emily Gale ◽  
...  
Keyword(s):  
Retinoic Acid ◽  
Avian Embryo ◽  
Rathke’S Pouch ◽  
Rathke's Pouch ◽  
Eye Field

Hypophysarer Zwergwuchs beim Deutschen Schäferhund [Pituitary Dwarfism in a German Shepherd Dog—author's trans]

1980 ◽  
Vol 17 (4) ◽  
pp. 406-421 ◽  
Author(s):  
R. Müller-Peddinghaus ◽  
M. F. El Etreby ◽  
J. Siefert ◽  
M. Ranke
Keyword(s):  
Growth Hormone ◽  
High Growth ◽  
Recessive Trait ◽  
German Shepherd ◽  
Serum Growth Hormone ◽  
Pituitary Dwarfism ◽  
Rathke’S Pouch ◽  
Rathke's Pouch ◽  
German Shepherd Dog ◽  
Normal Offspring

Pituitary Dwarfism in a German Shepherd Dog Pituitary dwarfism has been described in more than 20 German shepherd dogs. Some cases probably were caused by persistent cysts of Rathke's pouch. This is the first histopathological, immunohistochemical and endocrinological study. A 13-month-old, 7-kg, dwarf purebred German shepherd bitch with alopecia and hyper pigmentation was admitted to the clinic for euthanasia. Retardation of growth was noticed when the dog was about two months old. No littermates had this condition. Two subsequent breedings from the same parents produced normal offspring. The clinical parameters in our dog (hematology, function of liver and kidney) were normal. Grossly, the pituitary gland had small and large multiple cysts, which light microscopy showed to be exclusively within the adenohypophysis. The latter had pressure atrophy, and immunohistochemically showed only remnants of the hormone-producing cells (growth hormone—GH; prolactin—PRL; thyrotropin—TSH; luteinizing hormone—LH; adrenocorticotrophin—ACTH/MSH). The thyroid was relatively small, and histologically showed focally resting follicles without lumen. Endocrinological studies showed a surprisingly high value for serum growth hormone (cGH 4.1 ng/ml; normal range 1.8–3.8 ng/ml as determined by a specific homologous radioimmunoassay) and a pathologically low serum somatomedin (SM 0.132; normal value more than 0.50 unit/ml, determined by 35S incorporation in piglet rib cartilage). Hypothyroidism was verified by a low T4 binding value (T4 0.9 μg/100 ml; normal 4.1 ± 0.9 μg/100 ml) and a low thyroid binding index (TBI 0.54; normal 0.61 ± 0.05). While ACTH was lowered (ACTH <10 pg/ml; normal 74–210 pg/ml), cortisol was normal (0.81 μg/100 ml; normal 0.5–2.5 μg/100 ml). Pituitary dwarfism in the 13-month-old bitch can be ascribed to the persistence of one end of the ductus craniopharyngeus. Rathke's pouch. Pressure atrophy of the adenohypophysis led to the loss of most of the hormone-producing tissue. An increase in growth hormone with lowered somatomedin raises questions. We have no conclusive explanation for this, due to the present lack of knowledge of how growth is regulated. High growth hormone and low somatomedin values are found in Laron's syndrome in infants. The literature indicates that pituitary dwarfism in German shepherd dogs may be a hereditary autosomal recessive trait.

Three-dimensional studies of Prop1-expressing cells in the rat pituitary primordium of Rathke's pouch

2011 ◽  
Vol 346 (3) ◽  
pp. 339-346 ◽  
Author(s):  
Hideji Yako ◽  
Takako Kato ◽  
Saishu Yoshida ◽  
Kinji Inoue ◽  
Yukio Kato
Keyword(s):  
Three Dimensional ◽  
Rathke’S Pouch ◽  
Rathke's Pouch ◽  
Rat Pituitary

Ontogenesis of hypothalamic immunoreactive ACTH cells in vivo and in vitro: Role of Rathke's pouch

1983 ◽  
Vol 97 (1) ◽  
pp. 81-88 ◽  
Author(s):  
Shigeo Daikoku ◽  
Mika Chikamori ◽  
Tohru Adachi ◽  
Yoshihito Okamura ◽  
Tohru Nishiyama ◽  
...  
Keyword(s):  
Rathke’S Pouch ◽  
Rathke's Pouch
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