TRANSFORMATION IN VITRO OF [4-14C]DEHYDROEPIANDROSTERONE TO 7-OXYGENATED DERIVATIVES BY NORMAL EARLY HUMAN PLACENTAL TISSUE
SUMMARY Samples from three early human placentae were incubated with [4-14C]-dehydroepiandrosterone (DHA). It was found that [4-14C]DHA was transformed into 7-oxygenated derivatives in yields decreasing in the order: 7-oxo-DHA > 7β-hydroxy-DHA > 7α-hydroxy-DHA. These products were only slowly transformed into other derivatives.
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2000 ◽
Vol 85
(1)
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pp. 317-321
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2013 ◽
Vol 936
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pp. 80-87
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1991 ◽
Vol 73
(1)
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pp. 60-70
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1988 ◽
Vol 159
(1)
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pp. 42-47
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