scholarly journals A Unifying Approach for GFR Estimation: Recommendations of the NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Disease

2021 ◽  
pp. ASN.2021070988 ◽  
Author(s):  
Cynthia Delgado ◽  
Mukta Baweja ◽  
Deidra Crews ◽  
Nwamaka Eneanya ◽  
Crystal Gadegbeku ◽  
...  

A Task Force from the NKF and ASN developed recommendations for reassessing inclusion of race in the estimation of glomerular filtration rate (eGFR) in the U.S. The Task Force recommends immediate implementation of the CKD-EPI creatinine equation refit without the race variable in all laboratories because the calculation does not include race, it included diversity in its development, its potential adverse consequences do not disproportionately affect any one group, and it is immediately available to all laborataries. A second recommendation calls for national efforts to facilitate increased, routine, and timely use of cystatin C, especially to confirm eGFR in adults for clinical decision-making. A third recommendation encourages research on GFR estimation with new endogenous filtration markers and interventions to eliminate racial and ethnic disparities.

2020 ◽  
pp. 44-48
Author(s):  
V. A. Aleksandrov ◽  
L. N. Shilova ◽  
A. V. Aleksandrov

The development of renal dysfunction in patients with rheumatoid arthritis (RA) is due to the presence and severity of autoimmune disorders, chronic systemic inflammation, a multiplicity of comorbid conditions, and pharmacotherapy features. The most important parameter that describes the general condition of the kidneys is glomerular filtration rate (GFR). This review presents the data on the possibilities of modern methods for determining estimated GFR (e-GFR) and the specificity of their use in various clinical situations that accompany the course of RA. For the initial assessment of GFR in patients with RA it is advisable to use the measurement of e-GFR based on serum creatinine concentration using the CKD-EPI equation (2009) (with or without indexing by body surface area). In cases where the e-GFR equations are not reliable enough or the results of this test are insufficient for clinical decision making, the serum cystatin C level should be measured and the combined GFR calculation based on creatinine and cystatin C should be used.


2009 ◽  
Vol 28 (4) ◽  
pp. 247-250
Author(s):  
Shirley Brott

Come join us in sunny Phoenix! Conference planners have organized a fantastic lineup of professionals from across the U.S. to share the latest in neonatology and neonatal nursing for the 9th National Neonatal Nurses Conference. A sample of our speakers include Susan Ludington, CNM, PhD, FAAN, famous for her 1970s groundbreaking work in infant stimulation and in kangaroo care in the 1980s. She will share her newest studies regarding neonatal neurointensive care and how your care affects the infant’s brain. Biostatistician Dr. Mary Z. Mays will help guide the way to clinical decision making based on journal data with tools to determine whether evidence is statistically significant and clinically meaningful in her Monday afternoon workshop, “Statistics for Clinicians.” Preconference workshops include simulation techniques, pharmacology, leadership skills… and so much more! Check out the full conference schedule by going to academyonline.org or neonatalnetwork.com, and register today!


2011 ◽  
Vol 20 (4) ◽  
pp. 121-123
Author(s):  
Jeri A. Logemann

Evidence-based practice requires astute clinicians to blend our best clinical judgment with the best available external evidence and the patient's own values and expectations. Sometimes, we value one more than another during clinical decision-making, though it is never wise to do so, and sometimes other factors that we are unaware of produce unanticipated clinical outcomes. Sometimes, we feel very strongly about one clinical method or another, and hopefully that belief is founded in evidence. Some beliefs, however, are not founded in evidence. The sound use of evidence is the best way to navigate the debates within our field of practice.


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