Conditional standard errors of measurement, confidence interval, and reliability for individual level student growth percentiles

2018 ◽  
Author(s):  
Jinah Choi
Author(s):  
John A. Gallis ◽  
Fan Li ◽  
Elizabeth L. Turner

Cluster randomized trials, where clusters (for example, schools or clinics) are randomized to comparison arms but measurements are taken on individuals, are commonly used to evaluate interventions in public health, education, and the social sciences. Analysis is often conducted on individual-level outcomes, and such analysis methods must consider that outcomes for members of the same cluster tend to be more similar than outcomes for members of other clusters. A popular individual-level analysis technique is generalized estimating equations (GEE). However, it is common to randomize a small number of clusters (for example, 30 or fewer), and in this case, the GEE standard errors obtained from the sandwich variance estimator will be biased, leading to inflated type I errors. Some bias-corrected standard errors have been proposed and studied to account for this finite-sample bias, but none has yet been implemented in Stata. In this article, we describe several popular bias corrections to the robust sandwich variance. We then introduce our newly created command, xtgeebcv, which will allow Stata users to easily apply finite-sample corrections to standard errors obtained from GEE models. We then provide examples to demonstrate the use of xtgeebcv. Finally, we discuss suggestions about which finite-sample corrections to use in which situations and consider areas of future research that may improve xtgeebcv.


2019 ◽  
Vol 316 (6) ◽  
pp. F1114-F1123
Author(s):  
Andrew K. Timmons ◽  
Anna M. Korpak ◽  
Jenny Tan ◽  
Kathryn P. Moore ◽  
Cindy H. Liu ◽  
...  

Little is known about the population genetics of water balance. A recent meta-genome-wide association study on plasma sodium concentration identified novel loci of high biological plausibility, yet heritability of the phenotype has never been convincingly shown in European ancestry. The present study linked the Vietnam Era Twin Registry with the Department of Veterans Affairs VistA patient care clinical database. Participants ( n = 2,370, 59.6% monozygotic twins and 40.4% dizygotic twins) had a median of seven (interquartile range: 3−14) plasma sodium determinations between October 1999 and March 2017. Heritability of the mean plasma sodium concentration among all twins was 0.41 (95% confidence interval: 0.35−0.46) and 0.49 (95% confidence interval: 0.43−0.54) after exclusion of 514 twins with only a single plasma sodium determination. Heritability among Caucasian ( n = 1,958) and African-American ( n = 268) twins was 0.41 (95% confidence interval: 0.34−0.47) and 0.36 (95% confidence interval: 0.17−0.52), respectively. Exclusion of data from twins who had been prescribed medications known to impact systemic water balance had no effect. The ability of the present study to newly detect substantial heritability across multiple racial groups was potentially a function of the cohort size and relatedness, exclusion of sodium determinations confounded by elevated plasma glucose and/or reduced glomerular filtration rate, transformation of plasma sodium for the independent osmotic effect of plasma glucose, and use of multiple laboratory determinations per individual over a period of years. Individual-level plasma sodium concentration exhibited longitudinal stability (i.e., individuality); the degree to which individual-level means differed from the population mean was substantial, irrespective of the number of determinations. In aggregate, these data establish the heritability of plasma sodium concentration in European ancestry and corroborate its individuality.


2006 ◽  
Vol 98 (1) ◽  
pp. 237-252 ◽  
Author(s):  
Larry R. Price ◽  
Anna Lurie ◽  
Nambury Raju ◽  
Charles Wilkins ◽  
Jianjun Zhu

1985 ◽  
Vol 56 (2) ◽  
pp. 444-446
Author(s):  
B. J. Bushman

If an individual takes more than one MMPI the subscale scores are likely to vary. The individual giving the test may wish to identify significant changes between subscale scores. Standard errors of measurement may be beneficial in this regard. The purpose of this study was to compute the standard errors of measurement for each of the MMPI subscales. A table is also provided for individuals who wish to use these data.


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